> Unc-5 homolog B (C. elegans) (UNC5B)
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UGID:913744     UniGene Hs.522997     Homo sapiens (human)   UNC5B Links
Unc-5 homolog B (C. elegans) (UNC5B)

Human protein-coding gene UNC5B. Represented by 198 ESTs from 122 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 913744 - Hs.522997]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_734465.2 UNC5B gene product H. sapiens 100.0 944
NP_084046.2 Unc5b gene product M. musculus 93.2 944
NP_001082302.1 netrin receptor UNC5B precursor X. laevis 82.8 939
NP_001104619.1 unc5b gene product D. rerio 72.4 927
Other hits (2 of 28) [Show all]SpeciesId(%)Len(aa)
XP_003903863.1 PREDICTED: netrin receptor UNC5B isoform 1 P. anubis 99.0 944
XP_001106162.2 PREDICTED: netrin receptor UNC5B-like M. mulatta 98.9 944

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; connective tissue; testis; intestine; eye; uterus; embryonic tissue; uncharacterized tissue; mixed; pancreas; liver; bone; lung; kidney; mammary gland; ovary; mouth; skin; adrenal gland; stomach; bladder; larynx; spleen; vascular; prostate; muscle; lymph node; cervix
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 10
Map position: 10q22.1
UniSTS entry: Chr 10 A007B32
UniSTS entry: Chr 10 D5S1944
UniSTS entry: Chr 10 SHGC-56950
UniSTS entry: Chr 10 MARC_17640-17641:1019145113:1
UniSTS entry: Chr 14 D10S1759 [Map Viewer]
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (8)

AL049370.1 Homo sapiens mRNA; cDNA DKFZp586D0918 (from clone DKFZp586D0918) A
AB096256.1 Homo sapiens p53RDL1 mRNA for p53-regulated receptor for death and life, complete cds PA
AK128132.1 Homo sapiens cDNA FLJ46253 fis, clone TESTI4022158, highly similar to Netrin receptor UNC5B precursor P
AY358351.1 Homo sapiens clone DNA91779 GARS1883 (UNQ1883) mRNA, complete cds P
AK022859.1 Homo sapiens cDNA FLJ12797 fis, clone NT2RP2002066, highly similar to Rattus norvegicus transmembrane receptor Unc5H2 mRNA P
AK094595.1 Homo sapiens cDNA FLJ37276 fis, clone BRAMY2012426, highly similar to Rattus norvegicus transmembrane receptor Unc5H2 mRNA P
NM_001244889.1 Homo sapiens unc-5 homolog B (C. elegans) (UNC5B), transcript variant 2, mRNA PA
NM_170744.4 Homo sapiens unc-5 homolog B (C. elegans) (UNC5B), transcript variant 1, mRNA PA

EST sequences (10 of 198) [Show all sequences]

AA897641.1 Clone IMAGE:1503908 mixed 3' read
AA911800.1 Clone IMAGE:1519693 uncharacterized tissue 3' read A
AI141688.1 Clone IMAGE:1614259 uncharacterized tissue 3' read A
AI144009.1 Clone IMAGE:1698062 uterus 3' read A
CB044308.1 Clone IMAGE:3217700 intestine 3' read A
BX099120.1 Clone IMAGp998P095609_;_IMAGE:2265848 uterus A
BX089212.1 Clone IMAGp998J1975_;_IMAGE:24249 brain A
AI222384.1 Clone IMAGE:1843185 mixed 3' read
AI249948.1 Clone IMAGE:2004461 pancreas 3' read A
AI250054.1 Clone IMAGE:2004636 pancreas 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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