Melanoma antigen family D, 4 (MAGED4)

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UGID:913397 UniGene Hs.522650 Homo sapiens (human) MAGED4

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Melanoma antigen family D, 4 (MAGED4)

Human protein-coding gene MAGED4. Represented by 204 ESTs from 110 cDNA libraries. Corresponds to 4 reference sequences (different isoforms). [UniGene 913397 - Hs.522650]

SELECTED PROTEIN SIMILARITIES

Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.

Best Hits and Hits from model organisms		Species	Id(%)	Len(aa)
NP_001229291.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	MAGED4B gene product	H. sapiens	100.0	756
XP_003317515.2 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: melanoma-associated antigen D4-like	P. troglodytes	100.0	366
NP_062765.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	Maged1 gene product	M. musculus	73.5	343
Other hits (2 of 13) [Show all]		Species	Id(%)	Len(aa)
XP_001085892.2 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: melanoma-associated antigen D4 isoform 1	M. mulatta	98.9	740
XP_003917782.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: melanoma-associated antigen D4-like isoform 3	P. anubis	98.7	756

GENE EXPRESSION

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.

	EST Profile:	Approximate expression patterns inferred from EST sources. [Show more entries with profiles like this]
	GEO Profiles:	Experimental gene expression data (Gene Expression Omnibus).
	cDNA Sources:	brain; embryonic tissue; mixed; lung; uncharacterized tissue; uterus; thymus; prostate; blood; connective tissue; eye; vascular; bone; muscle; larynx; bone marrow; amniotic fluid; skin; ganglia; nerve; testis; intestine; pancreas; ovary; kidney; pharynx; mouth; heart; parathyroid

MAPPING POSITION

Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.

Chromosome:	X
Map position:	Xp11.22
UniSTS entry:	Chr X	WI-15363	[Map Viewer]

SEQUENCES

Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (14)

NM_177537.2	Homo sapiens melanoma antigen family D, 4B (MAGED4B), transcript variant 3, mRNA	PA
NM_177535.2	Homo sapiens melanoma antigen family D, 4B (MAGED4B), transcript variant 2, mRNA	PA
BC063838.1	Homo sapiens melanoma antigen family D, 4B, mRNA (cDNA clone MGC:74882 IMAGE:6185437), complete cds	PA
BC081566.1	Homo sapiens melanoma antigen family D, 4B, mRNA (cDNA clone MGC:88639 IMAGE:6292139), complete cds	PA
BC001207.1	Homo sapiens melanoma antigen family D, 4B, mRNA (cDNA clone IMAGE:3502168), complete cds	PA
AB040528.1	Homo sapiens MAGE-E1b mRNA, complete cds	P
AB040527.1	Homo sapiens MAGE-E1a mRNA, complete cds	P
AL136582.1	Homo sapiens mRNA; cDNA DKFZp761N1924 (from clone DKFZp761N1924)	P
NM_030801.3	Homo sapiens melanoma antigen family D, 4B (MAGED4B), transcript variant 1, mRNA	PA
AB058762.2	Homo sapiens mRNA for KIAA1859 protein, partial cds	PA
AF329733.1	Homo sapiens MAGED4 protein (MAGED4) mRNA, complete cds	P
AK098830.1	Homo sapiens cDNA FLJ25964 fis, clone CBR01704	PA
AF320908.1	Homo sapiens MAGE-D4 (MAGED4) mRNA, partial cds	P
NM_001242362.1	Homo sapiens melanoma antigen family D, 4B (MAGED4B), transcript variant 4, mRNA	PA

EST sequences (10 of 204) [Show all sequences]

T05461.1	Clone HFBCY89	brain		P
AI032138.1	Clone IMAGE:1611269	uncharacterized tissue	3' read
AI038647.1	Clone IMAGE:1658714	embryonic tissue	3' read
AI082447.1	Clone IMAGE:1661953	mixed	3' read	P
AI091646.1	Clone IMAGE:1566671	mixed	3' read	PA
AI131328.1	Clone IMAGE:1709945	heart	3' read	A
AI142536.1	Clone IMAGE:1703216	brain	3' read	PA
CB068911.1	Clone IMAGE:6554275	pancreas	3' read	PA
CB069074.1	Clone IMAGE:6554275	pancreas	5' read	P
AI174443.1	Clone IMAGE:1701699	kidney	3' read	A

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria