> Lysine (K)-specific demethylase 6A (KDM6A)
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UGID:913363     UniGene Hs.522616     Homo sapiens (human)   KDM6A Order cDNA clone, Links
Lysine (K)-specific demethylase 6A (KDM6A)

Human protein-coding gene KDM6A. Represented by 241 ESTs from 123 cDNA libraries. Corresponds to reference sequence NM_021140.2. [UniGene 913363 - Hs.522616]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_003954022.1 PREDICTED: lysine-specific demethylase 6A isoform 3 P. troglodytes 100.0 1452
NP_066963.2 KDM6A gene product H. sapiens 100.0 1400
XP_003917663.1 PREDICTED: lysine-specific demethylase 6A, partial P. anubis 100.0 1377
XP_002806253.1 PREDICTED: lysine-specific demethylase 6A M. mulatta 100.0 1198
XP_003360323.1 PREDICTED: lysine-specific demethylase 6A-like isoform 3 S. scrofa 99.8 1452
NP_033509.1 Kdm6a gene product M. musculus 98.9 1392
NP_001086774.1 lysine (K)-specific demethylase 6A X. laevis 91.7 1454
XP_697746.2 PREDICTED: lysine-specific demethylase 6A D. rerio 85.9 1389
NP_723550.2 Utx, isoform B D. melanogaster 69.2 929
NP_509450.1 Protein UTX-1 C. elegans 51.2 810
Other hits (2 of 35) [Show all]SpeciesId(%)Len(aa)
NP_001193504.1 lysine-specific demethylase 6A B. taurus 99.5 1452
XP_001492320.3 PREDICTED: lysine-specific demethylase 6A E. caballus 99.4 1378

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; mixed; prostate; uncharacterized tissue; lung; placenta; lymph node; blood; ovary; mammary gland; kidney; esophagus; testis; intestine; mouth; heart; uterus; embryonic tissue; adipose tissue; thymus; vascular; thyroid; skin; muscle; pineal gland; spleen; lymph; spinal cord; trachea; liver; connective tissue; stomach; eye; adrenal gland; ascites; nerve; bone
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: X
Map position: Xp11.2
UniSTS entry: G49474
UniSTS entry: Chr X 1376 [Map Viewer]
UniSTS entry: Chr X UTX_8713
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (23)

BX640694.1 Homo sapiens mRNA; cDNA DKFZp686N1481 (from clone DKFZp686N1481) PA
CR749602.1 Homo sapiens mRNA; cDNA DKFZp686A03225 (from clone DKFZp686A03225) PA
AB208795.1 Homo sapiens mRNA for ubiquitously transcribed tetratricopeptide repeat variant protein P
BC093868.1 Homo sapiens ubiquitously transcribed tetratricopeptide repeat, X chromosome, mRNA (cDNA clone MGC:120903 IMAGE:7939713), complete cds P
NM_021140.2 Homo sapiens lysine (K)-specific demethylase 6A (KDM6A), mRNA PA
BC113381.1 Homo sapiens ubiquitously transcribed tetratricopeptide repeat, X chromosome, mRNA (cDNA clone MGC:141941 IMAGE:8322433), complete cds P
EF491815.1 Homo sapiens clone UTY mRNA, partial sequence; alternatively spliced
AK307691.1 Homo sapiens cDNA, FLJ97639 P
AL831996.2 Homo sapiens mRNA; cDNA DKFZp451J023 (from clone DKFZp451J023) PA
AK294456.1 Homo sapiens cDNA FLJ61093 partial cds, highly similar to Ubiquitously transcribed X chromosome tetratricopeptide repeat protein P
AK304114.1 Homo sapiens cDNA FLJ54410 partial cds, highly similar to Ubiquitously transcribed X chromosometetratricopeptide repeat protein P
AK303430.1 Homo sapiens cDNA FLJ54396 complete cds, highly similar to Ubiquitously transcribed X chromosome tetratricopeptide repeat protein P
BC143278.1 Homo sapiens ubiquitously transcribed tetratricopeptide repeat, X chromosome, mRNA (cDNA clone MGC:176797 IMAGE:9051780), complete cds P
BC143277.1 Homo sapiens ubiquitously transcribed tetratricopeptide repeat, X chromosome, mRNA (cDNA clone MGC:176796 IMAGE:9051779), complete cds P
BC143275.1 Homo sapiens cDNA clone IMAGE:9051777, containing frame-shift errors P
BC143272.1 Homo sapiens ubiquitously transcribed tetratricopeptide repeat, X chromosome, mRNA (cDNA clone MGC:176791 IMAGE:9051774), complete cds P
DQ062678.1 Homo sapiens ubiquitously transcribed tetratricopeptide repeat protein X-linked, transcript variant 3 (UTX) mRNA, complete cds, alternatively spliced P
DQ062677.1 Homo sapiens ubiquitously transcribed tetratricopeptide repeat protein X-linked, transcript variant 5 (UTX) mRNA, complete cds, alternatively spliced P
DQ062676.1 Homo sapiens ubiquitously transcribed tetratricopeptide repeat protein X-linked, transcript variant 7 (UTX) mRNA, complete cds, alternatively spliced P
EU026291.1 Homo sapiens ubiquitously transcribed tetratricopeptide repeat protein X-linked transcript variant 6 (UTX) mRNA, complete cds, alternatively spliced P
EU026283.1 Homo sapiens ubiquitously transcribed tetratricopeptide repeat protein X-linked transcript variant 4 (UTX) mRNA, complete cds, alternatively spliced P
AF000992.1 Homo sapiens ubiquitous TPR motif, X isoform (UTX) mRNA, alternative transcript 1, complete cds PA
AF000993.1 Homo sapiens ubiquitous TPR motif, X isoform (UTX) mRNA, alternative transcript 2, complete cds PA

EST sequences (10 of 241) [Show all sequences]

R14781.1 Clone IMAGE:30291 brain 5' read P
AI003153.1 Clone IMAGE:1700024 kidney 3' read
AI079569.1 Clone IMAGE:1674391 mixed 3' read
AI079613.1 Clone IMAGE:1663687 skin 3' read
AI140752.1 Clone IMAGE:1690214 mixed 3' read P
BX108336.1 Clone IMAGp998C215814_;_IMAGE:2343116 lung
BX096433.1 Clone IMAGp998P231116_;_IMAGE:471046 uterus P
AI201586.1 Clone IMAGE:1708469 heart 3' read P
AI219360.1 Clone IMAGE:1759522 placenta 3' read
R27397.1 Clone IMAGE:132763 placenta 5' read P


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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