> Aldo-keto reductase family 1, member B1 (aldose reductase) (AKR1B1)
NCBI UniGene banner graphic
PubMed Nucleotide Protein Genome Structure Popset Taxonomy
 Search
NCBI

UniGene
Homepage
FAQs
Help
Query Tips
Build Info
Library Browser
DDD
Download UniGene

Related Databases
Gene
HomoloGene
EST
SRA

NIH cDNA Projects
MGC | ZGC | XGC
Finding cDNAs
UGID:911959     UniGene Hs.521212     Homo sapiens (human)   AKR1B1 Order cDNA clone, Links
Aldo-keto reductase family 1, member B1 (aldose reductase) (AKR1B1)

Human protein-coding gene AKR1B1. Represented by 1207 ESTs from 331 cDNA libraries. Corresponds to reference sequence NM_001628.2. [UniGene 911959 - Hs.521212]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_001138232.2 PREDICTED: aldose reductase P. troglodytes 100.0 315
NP_001619.1 AKR1B1 gene product H. sapiens 100.0 315
NP_033788.3 Akr1b3 gene product M. musculus 90.2 315
NP_001070715.1 si:dkey-180p18.9 gene product D. rerio 82.3 315
NP_001083398.1 aldo-keto reductase family 1, member B1 (aldose reductase) X. laevis 78.9 316
NP_648484.1 CG6084, isoform A D. melanogaster 66.2 313
NP_496925.1 Protein Y39G8B.1, isoform a C. elegans 52.2 315
XP_001694768.1 low CO2-induced aldose reductase C. reinhardtii 51.8 284
NP_179722.1 aldose-6-phosphate reductase (NADPH2) A. thaliana 46.1 293
NP_014763.1 Gcy1p S. cerevisiae 45.5 220
Other hits (2 of 58) [Show all]SpeciesId(%)Len(aa)
XP_001100679.1 PREDICTED: aldose reductase M. mulatta 99.4 315
XP_003896671.1 PREDICTED: aldose reductase P. anubis 98.7 315

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; kidney; placenta; uncharacterized tissue; lung; adrenal gland; mixed; eye; embryonic tissue; pancreas; skin; blood; testis; muscle; liver; intestine; ovary; parathyroid; heart; uterus; ear; bone marrow; prostate; pituitary gland; thyroid; vascular; bladder; lymph node; connective tissue; mammary gland; thymus; ascites; epididymis; lymph; trachea; cervix; stomach; spinal cord; spleen; bone; mouth; salivary gland; amniotic fluid; nerve; umbilical cord; adipose tissue; pineal gland; pharynx; ganglia
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 7
Map position: 7q35
UniSTS entry: Chr 11 J05017
UniSTS entry: Chr 11 WI-18828 [Map Viewer]
UniSTS entry: Chr 1 D1S1425
UniSTS entry: Chr 1 D11S2921
UniSTS entry: Chr 1 D11S3114
UniSTS entry: Chr 1 D8S2278
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (16)

NM_001628.2 Homo sapiens aldo-keto reductase family 1, member B1 (aldose reductase) (AKR1B1), mRNA PA
J04795.1 Human aldose reductase mRNA, complete cds P
J05017.1 Human aldose reductase mRNA, complete cds P
J05474.1 Human aldose reductase mRNA, complete cds P
CR450351.1 Homo sapiens full open reading frame cDNA clone RZPDo834H072D for gene AKR1B1, aldo-keto reductase family 1, member B1 (aldose reductase); complete cds; without stopcodon P
CR542203.1 Homo sapiens full open reading frame cDNA clone RZPDo834E1224D for gene AKR1B1, aldo-keto reductase family 1, member B1 (aldose reductase); complete cds, incl. stopcodon P
BT019859.1 Homo sapiens aldo-keto reductase family 1, member B1 (aldose reductase) mRNA, complete cds P
AB209796.1 Homo sapiens mRNA for aldo-keto reductase family 1, member B1 variant protein P
BC000260.1 Homo sapiens aldo-keto reductase family 1, member B1 (aldose reductase), mRNA (cDNA clone MGC:1804 IMAGE:3357652), complete cds PA
BC005387.1 Homo sapiens aldo-keto reductase family 1, member B1 (aldose reductase), mRNA (cDNA clone MGC:12512 IMAGE:3960811), complete cds PA
BC010391.1 Homo sapiens aldo-keto reductase family 1, member B1 (aldose reductase), mRNA (cDNA clone MGC:13648 IMAGE:4049736), complete cds PA
AK311339.1 Homo sapiens cDNA, FLJ18381 P
AK313439.1 Homo sapiens cDNA, FLJ93978, Homo sapiens aldo-keto reductase family 1, member B1 (aldosereductase) (AKR1B1), mRNA P
X15414.1 Human mRNA for aldose reductase (EC 1.1.1.2) P
AF328729.1 Homo sapiens CTCL tumor antigen HD-CL-07 mRNA, complete cds PA
M34720.1 Human aldose reductase mRNA, complete cds P

EST sequences (10 of 1207) [Show all sequences]

AA864267.1 Clone IMAGE:1460220 kidney 3' read
R14300.1 Clone IMAGE:28882 brain 5' read P
AA961983.1 Clone IMAGE:1592212 kidney 3' read A
AA905483.1 Clone IMAGE:1506597 mixed 3' read A
AA974934.1 Clone IMAGE:1558613 lung 3' read P
AA976198.1 Clone IMAGE:1558517 lung 3' read A
AA987700.1 Clone IMAGE:1593410 kidney 3' read
AA909589.1 Clone IMAGE:1522928 mixed 3' read A
AA909174.1 Clone IMAGE:1523212 mixed 3' read A
R19322.1 Clone IMAGE:33008 brain 5' read


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
NLM | NIH | UniGene | Privacy Statement | Disclaimer | NCBI Help