> WD repeat domain 46 (WDR46)
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UGID:910810     UniGene Hs.520063     Homo sapiens (human)   WDR46 Order cDNA clone, Links
WD repeat domain 46 (WDR46)

Human protein-coding gene WDR46. Represented by 970 ESTs from 283 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 910810 - Hs.520063]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_005443.3 WDR46 gene product H. sapiens 100.0 609
XP_518401.2 PREDICTED: WD repeat-containing protein 46 isoform 2 P. troglodytes 99.8 609
NP_065628.1 Wdr46 gene product M. musculus 92.4 617
NP_956917.1 wdr46 gene product D. rerio 64.5 567
NP_001087116.1 WD repeat domain 46 X. laevis 64.2 581
NP_502358.1 Protein WDR-46 C. elegans 55.1 459
NP_572441.1 CG2260 D. melanogaster 53.1 456
NP_011005.1 Utp7p S. cerevisiae 51.0 394
XP_956951.1 hypothetical protein NCU01502 N. crassa 50.0 414
XP_001690793.1 predicted protein C. reinhardtii 47.2 379
NP_187664.2 transducin/WD40 domain-containing protein A. thaliana 47.0 377
Other hits (2 of 52) [Show all]SpeciesId(%)Len(aa)
XP_001116178.1 PREDICTED: WD repeat-containing protein 46 isoform 4 M. mulatta 99.0 615
XP_003897489.1 PREDICTED: LOW QUALITY PROTEIN: WD repeat-containing protein 46 P. anubis 98.9 617

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; uncharacterized tissue; testis; skin; lung; intestine; spleen; placenta; uterus; kidney; connective tissue; liver; blood; mixed; embryonic tissue; pancreas; mammary gland; bone marrow; pineal gland; prostate; umbilical cord; muscle; lymph; eye; thymus; adrenal gland; vascular; cervix; tonsil; stomach; bladder; thyroid; trachea; esophagus; ovary; mouth; heart; lymph node; ganglia; salivary gland; pharynx; bone; nerve; adipose tissue; ascites; larynx
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 6
Map position: 6p21.3
UniSTS entry: Chr 6 RH12439 [Map Viewer]
UniSTS entry: Chr 6 D6S1234E [Map Viewer]
UniSTS entry: Chr 6 HSC0YF092 [Map Viewer]
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (11)

AF447870.1 Homo sapiens FP221 mRNA, complete cds PA
NM_005452.5 Homo sapiens WD repeat domain 46 (WDR46), transcript variant 1, mRNA PA
BC000388.2 Homo sapiens WD repeat domain 46, mRNA (cDNA clone MGC:8435 IMAGE:2821198), complete cds PA
AK292616.1 Homo sapiens cDNA FLJ77639 complete cds PA
AK292171.1 Homo sapiens cDNA FLJ77705 complete cds PA
AK311388.1 Homo sapiens cDNA, FLJ18430 P
AK308534.1 Homo sapiens cDNA, FLJ98575 P
AK315616.1 Homo sapiens cDNA, FLJ96697 P
AK298151.1 Homo sapiens cDNA FLJ51014 complete cds, highly similar to WD repeat protein 46 P
AK297925.1 Homo sapiens cDNA FLJ51004 complete cds, highly similar to WD repeat protein 46 PA
NM_001164267.1 Homo sapiens WD repeat domain 46 (WDR46), transcript variant 2, mRNA PA

EST sequences (10 of 970) [Show all sequences]

R14111.1 Clone IMAGE:27427 brain 5' read
AI128072.1 Clone IMAGE:1712743 uterus 3' read PA
AI204504.1 Clone IMAGE:1744727 lung 3' read A
CB161305.1 Clone L18POOL1n1-38-A09 liver 5' read P
CB110446.1 Clone L5HLK1-6-G12 liver 5' read P
CB137407.1 Clone L5HLK1-33-C05 liver 5' read P
CB113312.1 Clone L6ChoCK0-12-H02 liver 5' read P
CB116293.1 Clone L6ChoCK0-20-F02 liver 5' read P
CB150856.1 Clone C1SNU17-40-A05 cervix 5' read P
CB130588.1 Clone L12JSHC0-9-H04 liver 5' read P


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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