> Desmoplakin (DSP)
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UGID:910620     UniGene Hs.519873     Homo sapiens (human)   DSP Order cDNA clone, Links
Desmoplakin (DSP)

Human protein-coding gene DSP. Represented by 927 ESTs from 360 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 910620 - Hs.519873]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_004406.2 DSP gene product H. sapiens 100.0 2870
XP_518227.2 PREDICTED: desmoplakin isoform 3 P. troglodytes 99.9 2870
XP_001085012.1 PREDICTED: desmoplakin isoform 2 M. mulatta 99.5 2870
XP_003897070.1 PREDICTED: desmoplakin isoform 1 P. anubis 99.5 2870
NP_076331.2 Dsp gene product M. musculus 97.4 2881
NP_001088143.1 uncharacterized protein LOC494849 X. laevis 68.5 257
XP_002665846.2 PREDICTED: desmoplakin, partial D. rerio 57.3 2213
Other hits (2 of 18) [Show all]SpeciesId(%)Len(aa)
XP_225259.4 PREDICTED: desmoplakin isoform 2 R. norvegicus 97.8 2876
XP_002714279.1 PREDICTED: desmoplakin O. cuniculus 97.7 2820

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: skin; mouth; mammary gland; intestine; uterus; embryonic tissue; placenta; liver; pharynx; mixed; eye; pancreas; brain; lung; thyroid; larynx; muscle; uncharacterized tissue; thymus; connective tissue; esophagus; salivary gland; spleen; trachea; heart; kidney; prostate; cervix; testis; ovary; stomach; pituitary gland; ascites; parathyroid; ear; bladder; bone; adipose tissue; amniotic fluid; umbilical cord; lymph node; epididymis
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 6
Map position: 6p24
UniSTS entry: Chr 6 D6S2178
UniSTS entry: Chr 6 A004I41 [Map Viewer]
UniSTS entry: Chr 6 SHGC-35221 [Map Viewer]
UniSTS entry: Chr 6 RH46616 [Map Viewer]
UniSTS entry: Chr 6 GDB:185731
UniSTS entry: Chr 6 MARC_16807-16808:1042836779:1
UniSTS entry: Chr 6 DSP__4785
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (14)

AK130229.1 Homo sapiens cDNA FLJ26719 fis, clone PNC03379 P
NM_004415.2 Homo sapiens desmoplakin (DSP), transcript variant 1, mRNA P
NM_001008844.1 Homo sapiens desmoplakin (DSP), transcript variant 2, mRNA P
AF139065.1 Homo sapiens desmoplakin I mRNA, partial cds A
AB209992.1 Homo sapiens mRNA for DSP variant protein, partial cds, clone: bf04924 P
M77830.3 Homo sapiens desmoplakin I (DPI) mRNA, complete cds P
BC140802.1 Homo sapiens desmoplakin, mRNA (cDNA clone MGC:176479 IMAGE:9021670), complete cds P
AK301676.1 Homo sapiens cDNA FLJ51487 partial cds, highly similar to Desmoplakin P
AK304182.1 Homo sapiens cDNA FLJ61543 complete cds, highly similar to Desmoplakin P
AK296756.1 Homo sapiens cDNA FLJ53584 partial cds, highly similar to Desmoplakin P
BC144587.1 Homo sapiens cDNA clone IMAGE:9053117, containing frame-shift errors P
HM151899.1 Homo sapiens desmoplakin Ia mRNA, complete cds, alternatively spliced P
AB621818.1 Homo sapiens DSP mRNA for desmoplakin, partial cds, clone: HP08272-RBd85A01 P
J05211.1 Human desmoplakin mRNA, 3' end P

EST sequences (10 of 927) [Show all sequences]

AA961816.1 Clone IMAGE:1598429 uncharacterized tissue 3' read A
AI022862.1 Clone IMAGE:1650634 parathyroid 3' read P
AI023316.1 Clone IMAGE:1655308 mixed 3' read PA
AI025932.1 Clone IMAGE:1645894 parathyroid 3' read A
AI052505.1 Clone IMAGE:1675847 mixed 3' read PA
AI076962.1 Clone IMAGE:1666825 skin 3' read A
R20795.1 Clone IMAGE:130085 placenta 3' read A
R20904.1 Clone IMAGE:130085 placenta 5' read
AI078449.1 Clone IMAGE:1674481 mixed 3' read A
AI142882.1 Clone IMAGE:1661117 mixed 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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