> High mobility group AT-hook 1 (HMGA1)
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UGID:909552     UniGene Hs.518805     Homo sapiens (human)   HMGA1
High mobility group AT-hook 1 (HMGA1)

Human protein-coding gene HMGA1. Represented by 2732 ESTs from 333 cDNA libraries. Corresponds to 6 reference sequences (different isoforms). [UniGene 909552 - Hs.518805]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_001168943.1 uncharacterized protein LOC100382757 Z. mays 100.0 242
XP_001086020.1 PREDICTED: 40S ribosomal protein S3 M. mulatta 100.0 242
XP_003910477.1 PREDICTED: 40S ribosomal protein S3 P. anubis 100.0 242
NP_001238928.1 40S ribosomal protein S3 P. troglodytes 100.0 242
NP_000996.2 RPS3 gene product H. sapiens 100.0 242
NP_001038066.1 RPS3 gene product S. scrofa 100.0 242
NP_001029219.1 RPS3 gene product B. taurus 100.0 242
XP_004016377.1 PREDICTED: 40S ribosomal protein S3 O. aries 100.0 242
NP_036182.1 Rps3 gene product M. musculus 99.6 242
NP_001009239.1 Rps3 gene product R. norvegicus 99.6 242
XP_534008.1 PREDICTED: 40S ribosomal protein S3 isoform 1 C. lupus familiaris 99.6 242
XP_001494894.1 PREDICTED: 40S ribosomal protein S3-like E. caballus 99.6 242
XP_002708735.1 PREDICTED: ribosomal protein S3-like O. cuniculus 99.6 242
NP_001094409.1 40S ribosomal protein S3-A X. laevis 96.3 245
NP_957447.1 rps3 gene product D. rerio 95.1 244
NP_476632.1 ribosomal protein S3 D. melanogaster 83.9 230
XP_001699797.1 ribosomal protein S3, component of cytosolic 80S ribosome and 40S small subunit C. reinhardtii 83.3 216
NP_198403.1 40S ribosomal protein S3-3 A. thaliana 75.7 243
XP_956174.2 40S ribosomal protein S3 N. crassa 75.3 227
NP_498349.1 Protein RPS-3 C. elegans 75.0 236
NP_014221.3 ribosomal 40S subunit protein S3 S. cerevisiae 65.5 238
Other hits (2 of 51) [Show all]SpeciesId(%)Len(aa)
XP_001362617.1 PREDICTED: 40S ribosomal protein S3-like M. domestica 99.2 242
NP_001232278.1 LOC100190284 gene product T. guttata 98.8 242

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; placenta; skin; embryonic tissue; lung; testis; eye; pancreas; lymph; intestine; ovary; uncharacterized tissue; thymus; liver; ascites; lymph node; prostate; connective tissue; mammary gland; mixed; blood; muscle; bone; uterus; kidney; vascular; stomach; esophagus; cervix; heart; tonsil; bone marrow; spleen; umbilical cord; trachea; larynx; bladder; salivary gland; amniotic fluid; mouth; ganglia; parathyroid
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 6
Map position: 6p21
UniSTS entry: Chr 12 G11813
UniSTS entry: Chr 12 RH46847
UniSTS entry: Chr 6 MARC_1047-1048:991929773:1
UniSTS entry: Chr 12 A006X11
UniSTS entry: Chr 2 RH15892 [Map Viewer]
UniSTS entry: Chr 3 RH68863
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (28)

M23614.1 Human HMG-I protein isoform mRNA (HMGI gene), clone 7C
M23619.1 Human HMG-I protein isoform mRNA (HMGI gene), clone 6A
M23615.1 Human HMG-Y protein isoform mRNA (HMGI gene), clone 2B
M23616.1 Human HMG-Y protein isoform mRNA (HMGI gene), clone 8A
M23617.1 Human HMG-Y protein isoform mRNA (HMGI gene), clone 10A
M23618.1 Human HMG-Y protein isoform mRNA (HMGI gene), clone 11D
BT006774.1 Homo sapiens high mobility group AT-hook 1 mRNA, complete cds
AK130027.1 Homo sapiens cDNA FLJ26517 fis, clone KDN07769
NM_002131.3 Homo sapiens high mobility group AT-hook 1 (HMGA1), transcript variant 2, mRNA A
BC063434.1 Homo sapiens high mobility group AT-hook 1, mRNA (cDNA clone MGC:74577 IMAGE:5399570), complete cds A
BC067083.1 Homo sapiens high mobility group AT-hook 1, mRNA (cDNA clone MGC:71296 IMAGE:4110270), complete cds A
BC071864.1 Homo sapiens high mobility group AT-hook 1, mRNA (cDNA clone MGC:88534 IMAGE:6083428), complete cds A
BC078664.1 Homo sapiens cDNA clone IMAGE:3941503 PA
AF176039.1 Homo sapiens high mobility group protein-R mRNA, complete cds
BC004924.2 Homo sapiens high mobility group AT-hook 1, mRNA (cDNA clone MGC:4854 IMAGE:3605116), complete cds A
BC008963.2 Homo sapiens cDNA clone IMAGE:2962998, containing frame-shift errors A
BC008832.2 Homo sapiens high mobility group AT-hook 1, mRNA (cDNA clone MGC:12816 IMAGE:4308914), complete cds A
AK308245.1 Homo sapiens cDNA, FLJ98193
AK096863.1 Homo sapiens cDNA FLJ39544 fis, clone PUAEN2008980, moderately similar to HIGH MOBILITY GROUP PROTEIN HMG-I
NM_145905.2 Homo sapiens high mobility group AT-hook 1 (HMGA1), transcript variant 7, mRNA A
NM_145903.2 Homo sapiens high mobility group AT-hook 1 (HMGA1), transcript variant 5, mRNA A
NM_145902.2 Homo sapiens high mobility group AT-hook 1 (HMGA1), transcript variant 4, mRNA A
NM_145901.2 Homo sapiens high mobility group AT-hook 1 (HMGA1), transcript variant 3, mRNA A
NM_145899.2 Homo sapiens high mobility group AT-hook 1 (HMGA1), transcript variant 1, mRNA A
AK301434.1 Homo sapiens cDNA FLJ54188 complete cds, moderately similar to High mobility group protein HMG-I/HMG-Y
BC015789.1 Homo sapiens high mobility group AT-hook 1, mRNA (cDNA clone MGC:23654 IMAGE:4866014), complete cds A
X14957.1 Human hmgI mRNA for high mobility group protein I A
X14958.1 Human hmgI mRNA for high mobility group protein Y A

EST sequences (10 of 2732) [Show all sequences]

AA971843.1 Clone IMAGE:1584745 lung 3' read A
AA974473.1 Clone IMAGE:1372120 lymph node 3' read A
AA907188.1 Clone IMAGE:1521893 lung 3' read A
AI002542.1 Clone IMAGE:1601247 lung 3' read A
AI004016.1 Clone IMAGE:1625940 mixed 3' read
AI024458.1 Clone IMAGE:1639574 testis 3' read A
AI025695.1 Clone IMAGE:1644348 testis 3' read A
AI042404.1 Clone IMAGE:1665016 skin 3' read
AI074788.1 Clone IMAGE:1667015 skin 3' read A
AI075663.1 Clone IMAGE:1667102 skin 3' read


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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