> Ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) (UCHL1)
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UGID:909478     UniGene Hs.518731     Homo sapiens (human)   UCHL1 Order cDNA clone, Links
Ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) (UCHL1)

Human protein-coding gene UCHL1. Represented by 1346 ESTs from 251 cDNA libraries. Corresponds to reference sequence NM_004181.4. [UniGene 909478 - Hs.518731]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_003898669.1 PREDICTED: ubiquitin carboxyl-terminal hydrolase isozyme L1 isoform 1 P. anubis 100.0 222
XP_517163.2 PREDICTED: ubiquitin carboxyl-terminal hydrolase isozyme L1 isoform 7 P. troglodytes 100.0 222
NP_004172.2 UCHL1 gene product H. sapiens 100.0 222
XP_001097839.2 PREDICTED: ubiquitin carboxyl-terminal hydrolase isozyme L1-like M. mulatta 100.0 218
NP_035800.2 Uchl1 gene product M. musculus 96.9 222
NP_001090126.1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) X. laevis 74.0 222
NP_958885.1 uchl1 gene product D. rerio 67.4 217
NP_476940.1 ubiquitin carboxy-terminal hydrolase, isoform A D. melanogaster 46.9 224
NP_193484.1 ubiquitin C-terminal hydrolase 3 A. thaliana 45.9 207
Other hits (2 of 33) [Show all]SpeciesId(%)Len(aa)
NP_998928.1 UCHL1 gene product S. scrofa 98.7 222
NP_001075289.1 UCHL1 gene product E. caballus 98.2 222

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; lung; pancreas; eye; embryonic tissue; uncharacterized tissue; skin; kidney; ovary; testis; liver; prostate; uterus; lymph; connective tissue; heart; nerve; ear; bone; mixed; adrenal gland; placenta; pituitary gland; intestine; lymph node; muscle; vascular; mammary gland; bone marrow; mouth; ganglia; umbilical cord; stomach; bladder
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 4
Map position: 4p14
UniSTS entry: Chr 4 SHGC-67809 [Map Viewer]
UniSTS entry: Chr 4 SHGC-59749 [Map Viewer]
UniSTS entry: Uchl1
UniSTS entry: Chr 1 D8S2278
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (10)

NM_004181.4 Homo sapiens ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) (UCHL1), mRNA PA
AB209038.1 Homo sapiens mRNA for ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) variant protein
BC000332.2 Homo sapiens ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase), mRNA (cDNA clone MGC:8524 IMAGE:2822541), complete cds PA
BC005117.1 Homo sapiens ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase), mRNA (cDNA clone MGC:3601 IMAGE:2823559), complete cds PA
BC006305.2 Homo sapiens ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase), mRNA (cDNA clone MGC:13301 IMAGE:4106766), complete cds PA
AK055249.1 Homo sapiens cDNA FLJ30687 fis, clone FCBBF2000379
AK054579.1 Homo sapiens cDNA FLJ30017 fis, clone 3NB692000484, highly similar to Ubiquitin carboxyl-terminal hydrolase isozymeL1 (EC 3.4.19.12) P
AK315368.1 Homo sapiens cDNA, FLJ96414, highly similar to Homo sapiens ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) (UCHL1), mRNA P
BC018838.2 Homo sapiens ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase), mRNA (cDNA clone IMAGE:3349424) PA
X04741.1 Human mRNA for protein gene product (PGP) 9.5 P

EST sequences (10 of 1346) [Show all sequences]

AA961012.1 Clone IMAGE:1569764 lung 3' read A
AA863408.1 Clone IMAGE:1456878 kidney 3' read A
AA866016.1 Clone IMAGE:1459353 kidney 3' read
AA976958.1 Clone IMAGE:1587492 uncharacterized tissue 3' read A
AA983241.1 Clone IMAGE:1591940 kidney 3' read
AA993652.1 Clone IMAGE:1623604 embryonic tissue 3' read A
AI001721.1 Clone IMAGE:1613338 uncharacterized tissue 3' read A
R17444.1 Clone IMAGE:32319 brain 5' read P
AI042302.1 Clone IMAGE:1665758 skin 3' read A
AI073683.1 Clone IMAGE:1664396 skin 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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