> Wolfram syndrome 1 (wolframin) (WFS1)
NCBI UniGene banner graphic
PubMed Nucleotide Protein Genome Structure Popset Taxonomy
 Search
NCBI

UniGene
Homepage
FAQs
Help
Query Tips
Build Info
Library Browser
DDD
Download UniGene

Related Databases
Gene
HomoloGene
EST
SRA

NIH cDNA Projects
MGC | ZGC | XGC
Finding cDNAs
UGID:909349     UniGene Hs.518602     Homo sapiens (human)   WFS1 Order cDNA clone, Links
Wolfram syndrome 1 (wolframin) (WFS1)

Human protein-coding gene WFS1. Represented by 289 ESTs from 134 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 909349 - Hs.518602]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_005996.2 WFS1 gene product H. sapiens 100.0 889
XP_003310288.1 PREDICTED: wolframin P. troglodytes 99.5 845
NP_035846.1 Wfs1 gene product M. musculus 90.2 889
NP_001089845.1 Wolfram syndrome 1 (wolframin) X. laevis 81.7 859
XP_684510.2 PREDICTED: wolframin D. rerio 62.3 868
Other hits (2 of 16) [Show all]SpeciesId(%)Len(aa)
XP_001092811.1 PREDICTED: wolframin-like isoform 2 M. mulatta 98.9 889
XP_003898502.1 PREDICTED: wolframin P. anubis 98.5 889

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; testis; lung; uncharacterized tissue; prostate; placenta; uterus; eye; intestine; embryonic tissue; pancreas; ovary; kidney; skin; mammary gland; thymus; trachea; epididymis; thyroid; adrenal gland; larynx; stomach; lymph node; heart; bone; connective tissue; mixed; spleen; muscle; ganglia; nerve; umbilical cord; parathyroid; liver
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 4
Map position: 4p16.1
UniSTS entry: Chr 4 WI-21965 [Map Viewer]
UniSTS entry: Chr 4 SHGC-59709 [Map Viewer]
UniSTS entry: Chr 4 G01790
UniSTS entry: Chr 4 SHGC-59175 [Map Viewer]
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (7)

Y18064.1 Homo sapiens mRNA for wolframin P
AF084481.1 Homo sapiens transmembrane protein (WFS1) mRNA, complete cds P
NM_006005.3 Homo sapiens Wolfram syndrome 1 (wolframin) (WFS1), transcript variant 1, mRNA PA
BC069213.1 Homo sapiens Wolfram syndrome 1 (wolframin), mRNA (cDNA clone IMAGE:6110176), with apparent retained intron PA
AK312897.1 Homo sapiens cDNA, FLJ93343, Homo sapiens Wolfram syndrome 1 (wolframin) (WFS1), mRNA P
BC030130.2 Homo sapiens Wolfram syndrome 1 (wolframin), mRNA (cDNA clone MGC:12754 IMAGE:4127654), complete cds PA
NM_001145853.1 Homo sapiens Wolfram syndrome 1 (wolframin) (WFS1), transcript variant 2, mRNA PA

EST sequences (10 of 289) [Show all sequences]

AA989358.1 Clone IMAGE:1607075 mammary gland 3' read P
AI160539.1 Clone IMAGE:1721164 uterus 3' read A
AI279586.1 Clone IMAGE:1882392 lung 3' read A
AI288104.1 Clone IMAGE:1988222 uterus 3' read P
AI348540.1 Clone IMAGE:1910459 lung 3' read A
AI498210.1 Clone IMAGE:2164886 brain 3' read A
R53911.1 Clone IMAGE:138189 placenta 3' read A
AI560999.1 Clone IMAGE:2167973 brain 3' read A
AI669668.1 Clone IMAGE:2314933 prostate 3' read A
AI671815.1 Clone IMAGE:2307568 uncharacterized tissue 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
NLM | NIH | UniGene | Privacy Statement | Disclaimer | NCBI Help