> Glutamate-ammonia ligase (GLUL)
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UGID:909272     UniGene Hs.518525     Homo sapiens (human)   GLUL Order cDNA clone, Links
Glutamate-ammonia ligase (GLUL)

Human protein-coding gene GLUL. Represented by 2044 ESTs from 534 cDNA libraries. Corresponds to 3 reference sequences (different isoforms). [UniGene 909272 - Hs.518525]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_001114827.1 PREDICTED: glutamine synthetase isoform 1 M. mulatta 100.0 372
XP_003893479.1 PREDICTED: glutamine synthetase isoform 1 P. anubis 100.0 372
XP_001160639.1 PREDICTED: glutamine synthetase isoform 4 P. troglodytes 100.0 372
NP_002056.2 GLUL gene product H. sapiens 100.0 372
NP_032157.2 Glul gene product M. musculus 96.8 372
NP_878286.2 glulb gene product D. rerio 91.1 371
NP_001085214.1 uncharacterized protein LOC432308 X. laevis 90.9 372
NP_001041010.1 Protein GLN-3, isoform b C. elegans 75.8 383
NP_511123.2 glutamine synthetase 2, isoform C D. melanogaster 73.4 368
XP_960904.2 glutamine synthetase N. crassa 71.9 342
NP_175280.1 glutamine synthetase cytosolic isozyme 1-5 A. thaliana 65.2 352
NP_015360.2 glutamate--ammonia ligase S. cerevisiae 64.5 341
XP_001699902.1 glutamine synthetase C. reinhardtii 60.5 365
Other hits (2 of 58) [Show all]SpeciesId(%)Len(aa)
XP_001489285.2 PREDICTED: glutamine synthetase E. caballus 98.7 372
NP_001002965.1 GLUL gene product C. lupus familiaris 98.4 372

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; eye; testis; lung; pharynx; embryonic tissue; uterus; placenta; uncharacterized tissue; blood; mixed; liver; connective tissue; mammary gland; intestine; mouth; muscle; spleen; ovary; ganglia; thymus; prostate; skin; bone marrow; kidney; trachea; pancreas; spinal cord; bladder; nerve; heart; thyroid; stomach; larynx; lymph node; ear; salivary gland; esophagus; adipose tissue; ascites; bone; pituitary gland; adrenal gland; epididymis; vascular; amniotic fluid; cervix; parathyroid; lymph; tonsil
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 1
Map position: 1q31
UniSTS entry: Chr 1 Cda0jg12
UniSTS entry: Chr 1 SHGC-75989 [Map Viewer]
UniSTS entry: Chr 1 RH70547
UniSTS entry: Chr 1 SGC30288 [Map Viewer]
UniSTS entry: Chr 1 D1S2414 [Map Viewer]
UniSTS entry: Chr 1 D1S2009E
UniSTS entry: Chr 1 D1S290E [Map Viewer]
UniSTS entry: Chr 1 D1S2075E
UniSTS entry: Chr 1 D1S290E
UniSTS entry: Chr 2 RH70349 [Map Viewer]
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (19)

BC051726.1 Homo sapiens glutamate-ammonia ligase (glutamine synthetase), mRNA (cDNA clone MGC:48617 IMAGE:5261804), complete cds PA
BX537384.1 Homo sapiens mRNA; cDNA DKFZp686E0382 (from clone DKFZp686E0382); complete cds PA
AK122784.1 Homo sapiens cDNA FLJ16338 fis, clone TESTI2004920, highly similar to GLUTAMINE SYNTHETASE (EC 6.3.1.2) P
NM_002065.5 Homo sapiens glutamate-ammonia ligase (GLUL), transcript variant 1, mRNA PA
AY486122.1 Homo sapiens glutamine synthetase mRNA, complete cds P
NM_001033044.2 Homo sapiens glutamate-ammonia ligase (GLUL), transcript variant 2, mRNA PA
NM_001033056.2 Homo sapiens glutamate-ammonia ligase (GLUL), transcript variant 3, mRNA PA
AY513283.1 Homo sapiens proliferation-inducing protein 43 (PIG43) mRNA, complete cds P
BC127883.1 Homo sapiens glutamate-ammonia ligase (glutamine synthetase), mRNA (cDNA clone IMAGE:40131529), partial cds P
BC010037.2 Homo sapiens glutamate-ammonia ligase (glutamine synthetase), mRNA (cDNA clone MGC:19730 IMAGE:3545927), complete cds PA
BC011852.2 Homo sapiens glutamate-ammonia ligase (glutamine synthetase), mRNA (cDNA clone MGC:20322 IMAGE:4137547), complete cds PA
BC011700.2 Homo sapiens glutamate-ammonia ligase (glutamine synthetase), mRNA (cDNA clone MGC:19700 IMAGE:3528830), complete cds PA
BC018992.1 Homo sapiens glutamate-ammonia ligase (glutamine synthetase), mRNA (cDNA clone MGC:20095 IMAGE:3352740), complete cds PA
AY947343.1 Homo sapiens cell proliferation-inducing protein 59 (PIG59) mRNA, complete cds PA
AK301600.1 Homo sapiens cDNA FLJ57219 complete cds, highly similar to Glutamine synthetase (EC 6.3.1.2) PA
X59834.1 Human rearranged mRNA for glutamine synthase PA
Y00387.2 Human mRNA for glutamine synthetase (EC 6.3.1.2) P
BC031964.1 Homo sapiens glutamate-ammonia ligase (glutamine synthetase), mRNA (cDNA clone MGC:42945 IMAGE:4837475), complete cds PA
S70290.1 glutamine synthetase [human, tumorous liver, mRNA Partial, 2631 nt] P

EST sequences (10 of 2044) [Show all sequences]

AA960819.1 Clone IMAGE:1552217 uncharacterized tissue 3' read P
R15943.1 Clone IMAGE:53028 brain 5' read P
R15036.1 Clone IMAGE:29470 brain 5' read
AA987234.1 Clone IMAGE:1604252 lung 3' read P
AA993225.1 Clone IMAGE:1625097 embryonic tissue 3' read
AI000103.1 Clone IMAGE:1609836 mammary gland 3' read
AI028153.1 Clone IMAGE:1646165 parathyroid 3' read A
AI090714.1 Clone IMAGE:1640138 testis 3' read P
AA887074.1 Clone IMAGE:1476402 uncharacterized tissue 3' read P
AI124856.1 Clone IMAGE:1539650 brain 3' read


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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