> SRY (sex determining region Y)-box 2 (SOX2)
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UGID:909185     UniGene Hs.518438     Homo sapiens (human)   SOX2 Order cDNA clone, Links
SRY (sex determining region Y)-box 2 (SOX2)

Human protein-coding gene SOX2. Represented by 203 ESTs from 77 cDNA libraries. Corresponds to reference sequence NM_003106.3. [UniGene 909185 - Hs.518438]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_001098933.1 SOX2 gene product B. taurus 100.0 319
NP_001136412.1 SOX2 gene product M. mulatta 100.0 318
NP_003097.1 SOX2 gene product H. sapiens 100.0 316
XP_545216.3 PREDICTED: transcription factor SOX-2 C. lupus familiaris 99.7 323
XP_003894832.1 PREDICTED: transcription factor SOX-2-like P. anubis 99.7 318
NP_035573.3 Sox2 gene product M. musculus 99.4 318
NP_001081691.1 transcription factor Sox-2 X. laevis 93.2 310
NP_998283.1 sox2 gene product D. rerio 92.4 314
NP_741836.1 Protein SOX-2, isoform a C. elegans 81.0 121
NP_524735.1 SoxNeuro, isoform A D. melanogaster 63.6 343
Other hits (2 of 32) [Show all]SpeciesId(%)Len(aa)
NP_001102651.1 Sox2 gene product R. norvegicus 99.4 318
XP_516895.3 PREDICTED: transcription factor SOX-2 P. troglodytes 99.4 318

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; embryonic tissue; lung; eye; muscle; uncharacterized tissue; esophagus; testis; pituitary gland; mixed; ear; ascites; pancreas; ovary; mouth; intestine; placenta; kidney; thymus; pineal gland
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 3
Map position: 3q26.3-q27
UniSTS entry: Chr 3 RH66812
UniSTS entry: Chr 3 Sox2
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (5)

L07335.1 Homo sapiens (clone 6AR33) HMG box mRNA, 3' end cds PA
NM_003106.3 Homo sapiens SRY (sex determining region Y)-box 2 (SOX2), mRNA PA
BC013923.2 Homo sapiens SRY (sex determining region Y)-box 2, mRNA (cDNA clone MGC:2413 IMAGE:2823424), complete cds PA
AK312595.1 Homo sapiens cDNA, FLJ92971, highly similar to Homo sapiens SRY (sex determining region Y)-box 2 (SOX2), mRNA P
Z31560.1 H.sapiens sox-2 mRNA (partial) P

EST sequences (10 of 203) [Show all sequences]

AI052267.1 Clone IMAGE:1670050 brain 3' read P
AI056908.1 Clone IMAGE:1669608 brain 3' read P
AI073494.1 Clone IMAGE:1640265 testis 3' read P
AI094794.1 Clone IMAGE:1687037 brain 3' read P
AI096977.1 Clone IMAGE:1702774 brain 3' read P
AI097136.1 Clone IMAGE:1704535 brain 3' read P
AI146367.1 Clone IMAGE:1702724 brain 3' read P
AI146406.1 Clone IMAGE:1685935 brain 3' read P
AI151028.1 Clone IMAGE:1704802 brain 3' read P
AI161208.1 Clone IMAGE:1703983 brain 3' read


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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