Chromosome 22 open reading frame 46 (C22orf46)

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UGID:908400 UniGene Hs.517653 Homo sapiens (human) C22orf46

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Chromosome 22 open reading frame 46 (C22orf46)

Human protein-coding gene C22orf46. Represented by 96 ESTs from 74 cDNA libraries. Corresponds to reference sequence NM_001142964.1. [UniGene 908400 - Hs.517653]

SELECTED PROTEIN SIMILARITIES

Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.

Best Hits and Hits from model organisms		Species	Id(%)	Len(aa)
NP_001136436.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	C22orf46 gene product	H. sapiens	100.0	242
NP_001159947.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	uncharacterized protein LOC328573	M. musculus	56.1	1254
Other hits (2 of 8) [Show all]		Species	Id(%)	Len(aa)
XP_001101171.2 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: hypothetical protein LOC712231	M. mulatta	91.6	239
XP_004007686.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: uncharacterized protein C22orf46 homolog	O. aries	69.3	244

GENE EXPRESSION

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.

	EST Profile:	Approximate expression patterns inferred from EST sources. [Show more entries with profiles like this]
	GEO Profiles:	Experimental gene expression data (Gene Expression Omnibus).
	cDNA Sources:	brain; mammary gland; lung; thyroid; embryonic tissue; eye; testis; cervix; pancreas; placenta; intestine; connective tissue; skin; muscle; mixed; uterus; uncharacterized tissue; liver; kidney; bladder; thymus; ganglia; blood; prostate; larynx; adrenal gland; salivary gland; vascular; bone; heart

MAPPING POSITION

Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.

Chromosome:	22
Map position:	22q13.2
UniSTS entry:	Chr 22	RH74961

SEQUENCES

Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (5)

AK027237.1	Homo sapiens cDNA: FLJ23584 fis, clone LNG14307	PA
BC007210.1	Homo sapiens hypothetical FLJ23584, mRNA (cDNA clone MGC:14863 IMAGE:3344580), complete cds	PA
AK095008.1	Homo sapiens cDNA FLJ37689 fis, clone BRHIP2014373	P
NM_001142964.1	Homo sapiens chromosome 22 open reading frame 46 (C22orf46), mRNA	PA
BC035403.1	Homo sapiens hypothetical FLJ23584, mRNA (cDNA clone IMAGE:4823656)	PA

EST sequences (10 of 96) [Show all sequences]

R17336.1	Clone IMAGE:32298	brain	5' read
AI126649.1	Clone IMAGE:1736075	testis	3' read
CB158387.1	Clone L18POOL1n1-31-E06	liver	5' read	P
AI290059.1	Clone IMAGE:1990893	uterus	3' read	A
AI492230.1	Clone IMAGE:2108642	uncharacterized tissue	3' read	A
AI766137.1	Clone IMAGE:2386119	kidney	3' read	A
BX281640.1	Clone IMAGp998O0513336_;_IMAGE:6063580	skin		P
AI948811.1	Clone IMAGE:2472427	kidney	3' read	A
CD519125.1	Clone IMAGE:30400149	brain	5' read	P
CD558924.1	Clone IMAGE:30400149	brain	5' read	P

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria