> Minichromosome maintenance complex component 5 (MCM5)
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UGID:908329     UniGene Hs.517582     Homo sapiens (human)   MCM5
Minichromosome maintenance complex component 5 (MCM5)

Human protein-coding gene MCM5. Represented by 1163 ESTs from 325 cDNA libraries. Corresponds to reference sequence NM_006739.3. [UniGene 908329 - Hs.517582]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_006730.2 MCM5 gene product H. sapiens 100.0 733
XP_003905513.1 PREDICTED: DNA replication licensing factor MCM5 isoform 1 P. anubis 99.9 733
XP_001156025.1 PREDICTED: DNA replication licensing factor MCM5 isoform 4 P. troglodytes 99.9 733
XP_002798391.1 PREDICTED: DNA replication licensing factor MCM5-like M. mulatta 99.7 674
NP_032592.2 Mcm5 gene product M. musculus 97.3 733
NP_001080893.1 DNA replication licensing factor mcm5-A X. laevis 91.3 734
NP_848523.2 mcm5 gene product D. rerio 87.6 735
NP_524308.2 minichromosome maintenance 5 D. melanogaster 79.1 732
NP_497858.1 Protein MCM-5 C. elegans 74.4 758
XP_961537.1 DNA replication licensing factor mcm5 N. crassa 66.5 720
NP_013376.1 Mcm5p S. cerevisiae 66.0 770
NP_178812.1 minichromosome maintenance protein 5 (cell division control protein 46) A. thaliana 65.4 725
XP_001689975.1 minichromosome maintenance protein 5 C. reinhardtii 61.9 603
Other hits (2 of 62) [Show all]SpeciesId(%)Len(aa)
XP_001499944.1 PREDICTED: DNA replication licensing factor MCM5 isoform 1 E. caballus 99.2 733
XP_853134.2 PREDICTED: DNA replication licensing factor MCM5 C. lupus familiaris 99.0 684

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; uncharacterized tissue; skin; testis; placenta; embryonic tissue; thymus; blood; eye; uterus; spleen; intestine; lymph; liver; prostate; lung; ascites; ovary; connective tissue; mouth; mixed; vascular; mammary gland; pancreas; lymph node; kidney; esophagus; cervix; bone marrow; muscle; salivary gland; bone; stomach; heart; trachea; adrenal gland; tonsil; thyroid; bladder; pharynx; pituitary gland
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 22
Map position: 22q13.1
UniSTS entry: Chr 22 SGC35494
UniSTS entry: STS-X74795
UniSTS entry: Chr 22 RH91329
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (14)

AK130620.1 Homo sapiens cDNA FLJ27110 fis, clone SPL05630, highly similar to DNA replication licensing factor MCM5 P
AK122853.1 Homo sapiens cDNA FLJ16474 fis, clone BRSSN2012254, highly similar to DNA replication licensing factor MCM5 P
CR456517.1 Homo sapiens MCM5 full length open reading frame (ORF) cDNA clone (cDNA clone C22ORF:pGEM.MCM5) P
NM_006739.3 Homo sapiens minichromosome maintenance complex component 5 (MCM5), mRNA PA
AK223323.1 Homo sapiens mRNA for minichromosome maintenance deficient protein 5 variant, clone: TMS07715 P
BC000142.1 Homo sapiens minichromosome maintenance complex component 5, mRNA (cDNA clone MGC:5315 IMAGE:2900229), complete cds PA
BC003656.2 Homo sapiens minichromosome maintenance complex component 5, mRNA (cDNA clone MGC:4773 IMAGE:3542201), complete cds PA
AK291136.1 Homo sapiens cDNA FLJ78580 complete cds, highly similar to Homo sapiens MCM5 minichromosome maintenance deficient 5, cell division cycle 46 (MCM5), mRNA P
AK308343.1 Homo sapiens cDNA, FLJ98291 P
AK312533.1 Homo sapiens cDNA, FLJ92902, Homo sapiens MCM5 minichromosome maintenance deficient 5, celldivision cycle 46 (S. cerevisiae) (MCM5), mRNA P
AK301121.1 Homo sapiens cDNA FLJ54759 complete cds, highly similar to DNA replication licensing factor MCM5 P
AK298624.1 Homo sapiens cDNA FLJ55743 complete cds, highly similar to DNA replication licensing factor MCM5 PA
D83986.1 Homo sapiens mRNA for DNA replication licensing factor (huMCM5), complete cds P
X74795.2 H.sapiens P1-Cdc46 mRNA PA

EST sequences (10 of 1163) [Show all sequences]

AA922417.1 Clone IMAGE:1486379 mouth 3' read A
AA972621.1 Clone IMAGE:1583001 mixed 3' read A
AA906839.1 Clone IMAGE:1523978 mixed 3' read A
AI087817.1 Clone IMAGE:1567094 mixed 3' read PA
BX111302.1 Clone IMAGp998A24871_;_IMAGE:376607 heart P
AI190846.1 Clone IMAGE:1732960 heart 3' read P
CB136903.1 Clone L5HLK1-40-G07 liver 5' read P
CB151993.1 Clone B1T694954-17-A03 brain 5' read P
CB140803.1 Clone L15CKK1-33-B10 liver 5' read P
CB141414.1 Clone L15CKK1-30-G11 liver 5' read P


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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