> DiGeorge syndrome critical region gene 2 (DGCR2)
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UGID:908104     UniGene Hs.517357     Homo sapiens (human)   DGCR2 Order cDNA clone, Links
DiGeorge syndrome critical region gene 2 (DGCR2)

Human protein-coding gene DGCR2. Represented by 1692 ESTs from 346 cDNA libraries. Corresponds to 5 reference sequences (different isoforms). [UniGene 908104 - Hs.517357]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_005128.1 DGCR2 gene product H. sapiens 100.0 549
XP_530360.2 PREDICTED: integral membrane protein DGCR2/IDD isoform 3 P. troglodytes 100.0 546
XP_003905255.1 PREDICTED: integral membrane protein DGCR2/IDD isoform 1 P. anubis 99.8 546
NP_034178.2 Dgcr2 gene product M. musculus 96.9 548
NP_001086166.1 DiGeorge syndrome critical region gene 2 precursor X. laevis 85.4 548
NP_001002656.1 dgcr2 gene product D. rerio 78.8 532
Other hits (2 of 19) [Show all]SpeciesId(%)Len(aa)
XP_002798315.1 PREDICTED: integral membrane protein DGCR2/IDD-like M. mulatta 99.2 511
XP_543554.3 PREDICTED: integral membrane protein DGCR2/IDD isoform 2 C. lupus familiaris 97.2 544

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; testis; uncharacterized tissue; embryonic tissue; lung; pancreas; uterus; mammary gland; placenta; trachea; mixed; cervix; kidney; ovary; vascular; eye; intestine; spleen; mouth; connective tissue; nerve; adrenal gland; stomach; thymus; prostate; lymph node; skin; thyroid; liver; bone marrow; blood; muscle; epididymis; lymph; ascites; heart; bone; esophagus; bladder; adipose tissue; larynx; salivary gland; spinal cord; ganglia; parathyroid; pituitary gland
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 22
Map position: 22q11.21
UniSTS entry: Chr 22 A001T42
UniSTS entry: Chr 22 G19640
UniSTS entry: Chr 22 RH25381
UniSTS entry: Chr 22 G19956
UniSTS entry: Chr 22 A002D20
UniSTS entry: Chr 22 D22S1117
UniSTS entry: Chr 22 SGC31562 [Map Viewer]
UniSTS entry: Chr 22 D22S1611
UniSTS entry: Chr 22 D22S1573
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (22)

NM_005137.2 Homo sapiens DiGeorge syndrome critical region gene 2 (DGCR2), transcript variant 1, mRNA PA
CR456433.1 Homo sapiens DGCR2 full length open reading frame (ORF) cDNA clone (cDNA clone C22ORF:pGEM.DGCR2.V2) P
CR936871.1 Homo sapiens mRNA; cDNA DKFZp686I1730 (from clone DKFZp686I1730) PA
X83545.1 H.sapiens mRNA for a cell surface protein P
D79985.1 Homo sapiens KIAA0163 mRNA, complete cds P
AK291670.1 Homo sapiens cDNA FLJ75878 complete cds, highly similar to Homo sapiens DiGeorge syndrome critical region gene 2, mRNA P
X84076.1 H.sapiens mRNA for DGCR2 P
BC032430.1 Homo sapiens DiGeorge syndrome critical region gene 2, mRNA (cDNA clone MGC:40330 IMAGE:5243412), complete cds P
FJ032369.1 Homo sapiens DiGeorge syndrome critical region protein 2 (DGCR2) mRNA, complete cds, alternatively spliced P
BC035425.1 Homo sapiens DiGeorge syndrome critical region gene 2, mRNA (cDNA clone IMAGE:4184290) P
BC020339.1 Homo sapiens DiGeorge syndrome critical region gene 2, mRNA (cDNA clone IMAGE:4180979) P
L46352.1 Homo sapiens cell surface protein (IDD) mRNA, exon 1 fragment, with a polymorphism at position 234, (X83545 bases 1334-1620) P
AK304382.1 Homo sapiens cDNA FLJ50402 complete cds, highly similar to Integral membrane protein DGCR2/IDD precursor P
AK303130.1 Homo sapiens cDNA FLJ54340 complete cds, highly similar to Integral membrane protein DGCR2/IDD precursor P
AK296337.1 Homo sapiens cDNA FLJ50553 complete cds, highly similar to Integral membrane protein DGCR2/IDD precursor P
AK295697.1 Homo sapiens cDNA FLJ50536 complete cds, highly similar to Integral membrane protein DGCR2/IDD precursor P
L77560.1 Homo sapiens LAN mRNA, 3' end P
NM_001173534.1 Homo sapiens DiGeorge syndrome critical region gene 2 (DGCR2), transcript variant 3, mRNA PA
NM_001173533.1 Homo sapiens DiGeorge syndrome critical region gene 2 (DGCR2), transcript variant 2, mRNA PA
NM_001184781.1 Homo sapiens DiGeorge syndrome critical region gene 2 (DGCR2), transcript variant 4, mRNA P
NR_033674.1 Homo sapiens DiGeorge syndrome critical region gene 2 (DGCR2), transcript variant 5, non-coding RNA PA
BC040500.1 Homo sapiens DiGeorge syndrome critical region gene 2, mRNA (cDNA clone MGC:33836 IMAGE:5272271), complete cds PA

EST sequences (10 of 1692) [Show all sequences]

AI004143.1 Clone IMAGE:1619569 testis 3' read A
AI028408.1 Clone IMAGE:1649602 parathyroid 3' read
AA927602.1 Clone IMAGE:1563284 mixed 3' read
AI073830.1 Clone IMAGE:1565840 mixed 3' read P
AI082326.1 Clone IMAGE:1661863 mixed 3' read
AI094904.1 Clone IMAGE:1687088 brain 3' read
AI139281.1 Clone IMAGE:1710522 uterus 3' read A
CB054550.1 Clone IMAGE:3291519 brain 3' read A
CB054551.1 Clone IMAGE:3291519 brain 5' read
AI147874.1 Clone IMAGE:1698125 uterus 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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