> Acyl-CoA synthetase short-chain family member 2 (ACSS2)
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UGID:907781     UniGene Hs.517034     Homo sapiens (human)   ACSS2
Acyl-CoA synthetase short-chain family member 2 (ACSS2)

Human protein-coding gene ACSS2. Represented by 608 ESTs from 244 cDNA libraries. Corresponds to 3 reference sequences (different isoforms). [UniGene 907781 - Hs.517034]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_001070020.2 ACSS2 gene product H. sapiens 100.0 713
XP_514806.3 PREDICTED: acetyl-coenzyme A synthetase, cytoplasmic isoform 11 P. troglodytes 99.9 714
NP_062785.2 Acss2 gene product M. musculus 96.2 700
NP_001085453.1 acyl-CoA synthetase short-chain family member 2, gene 2 X. laevis 78.8 671
XP_001919051.3 PREDICTED: acetyl-coenzyme A synthetase, cytoplasmic D. rerio 77.8 580
NP_730611.1 acetyl coenzyme A synthase, isoform A D. melanogaster 70.9 663
XP_001700210.1 acetyl CoA synthetase C. reinhardtii 67.7 653
NP_198504.1 acetyl-CoA synthetase A. thaliana 66.5 648
NP_001021206.1 Protein ACS-19, isoform b C. elegans 60.5 653
XP_963677.2 acetate--CoA ligase N. crassa 55.1 639
NP_013254.1 acetate--CoA ligase ACS2 S. cerevisiae 53.5 639
Other hits (2 of 60) [Show all]SpeciesId(%)Len(aa)
XP_001103094.1 PREDICTED: acetyl-coenzyme A synthetase, cytoplasmic isoform 8 M. mulatta 99.2 713
XP_003904881.1 PREDICTED: acetyl-coenzyme A synthetase, cytoplasmic P. anubis 98.5 725

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; intestine; testis; kidney; mixed; mouth; placenta; cervix; thyroid; muscle; esophagus; spleen; thymus; liver; lymph; lung; skin; adrenal gland; blood; prostate; uterus; ovary; heart; bladder; uncharacterized tissue; pancreas; trachea; mammary gland; larynx; eye; spinal cord; stomach; embryonic tissue; bone marrow; ascites; connective tissue; pineal gland; ganglia; bone; nerve; vascular; parathyroid
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 20
Map position: 20q11.22
UniSTS entry: Chr 20 D20S106 [Map Viewer]
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (17)

AK000162.1 Homo sapiens cDNA FLJ20155 fis, clone COL08754, highly similar to ACSA_ECOLI ACETYL-COENZYME A SYNTHETASE PA
AK000188.1 Homo sapiens cDNA FLJ20181 fis, clone COLF0188, highly similar to ACSA_ECOLI ACETYL-COENZYME A SYNTHETASE PA
BC073846.1 Homo sapiens acyl-CoA synthetase short-chain family member 2, mRNA (cDNA clone IMAGE:5219243), partial cds PA
CR749716.1 Homo sapiens mRNA; cDNA DKFZp762G026 (from clone DKFZp762G026) PA
NM_018677.3 Homo sapiens acyl-CoA synthetase short-chain family member 2 (ACSS2), transcript variant 1, mRNA PA
AL359946.1 Homo sapiens mRNA; cDNA DKFZp762G026 (from clone DKFZp762G026) PA
AF263614.1 Homo sapiens acetyl-CoA synthetase mRNA, complete cds P
BC098422.1 Homo sapiens acyl-CoA synthetase short-chain family member 2, mRNA (cDNA clone MGC:104804 IMAGE:5798672), complete cds PA
AK022608.1 Homo sapiens cDNA FLJ12546 fis, clone NT2RM4000616, moderately similar to ACETYL-COENZYME A SYNTHETASE (EC 6.2.1.1) P
AK025990.1 Homo sapiens cDNA: FLJ22337 fis, clone HRC05961, highly similar to AF263614 Homo sapiens acetyl-CoA synthetase mRNA PA
NM_001076552.2 Homo sapiens acyl-CoA synthetase short-chain family member 2 (ACSS2), transcript variant 2, mRNA PA
BC010141.2 Homo sapiens acyl-CoA synthetase short-chain family member 2, mRNA (cDNA clone IMAGE:4131932), partial cds PA
BC012172.1 Homo sapiens acyl-CoA synthetase short-chain family member 2, mRNA (cDNA clone MGC:20418 IMAGE:4643236), complete cds PA
AK098026.1 Homo sapiens cDNA FLJ40707 fis, clone THYMU2026835, highly similar to Acetyl-coenzyme A synthetase, cytoplasmic (EC 6.2.1.1) P
AK092281.1 Homo sapiens cDNA FLJ34962 fis, clone NTONG2003897, highly similar to Homo sapiens acetyl-CoA synthetase mRNA P
AK293634.1 Homo sapiens cDNA FLJ53719 complete cds, highly similar to Acetyl-coenzyme A synthetase, cytoplasmic (EC6.2.1.1) P
NM_001242393.1 Homo sapiens acyl-CoA synthetase short-chain family member 2 (ACSS2), transcript variant 3, mRNA PA

EST sequences (10 of 608) [Show all sequences]

AA995151.1 Clone IMAGE:1627027 mixed 3' read
AI000729.1 Clone IMAGE:1636953 kidney 3' read A
AA887195.1 Clone IMAGE:1500790 kidney 3' read
AI003970.1 Clone IMAGE:1624435 embryonic tissue 3' read A
AI032882.1 Clone IMAGE:1646756 parathyroid 3' read A
AI041626.1 Clone IMAGE:1663838 skin 3' read A
AI052091.1 Clone IMAGE:1652645 mixed 3' read
R20503.1 Clone IMAGE:35644 brain 5' read
AI090855.1 Clone IMAGE:1640197 testis 3' read A
R21717.1 Clone IMAGE:36317 brain 5' read P


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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