> Hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit (HADHB)
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UGID:906595     UniGene Hs.515848     Homo sapiens (human)   HADHB Order cDNA clone, Links
Hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit (HADHB)

Human protein-coding gene HADHB. Represented by 1895 ESTs from 408 cDNA libraries. Corresponds to reference sequence NM_000183.2. [UniGene 906595 - Hs.515848]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_001029291.1 HADHB gene product P. troglodytes 100.0 474
NP_000174.1 HADHB gene product H. sapiens 100.0 473
XP_003908418.1 PREDICTED: trifunctional enzyme subunit beta, mitochondrial isoform 1 P. anubis 99.8 474
XP_001086547.2 PREDICTED: trifunctional enzyme subunit beta, mitochondrial M. mulatta 99.8 464
NP_663533.1 Hadhb gene product M. musculus 95.0 474
NP_001080077.1 hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit X. laevis 88.9 469
NP_956313.1 hadhb gene product D. rerio 86.2 470
NP_477378.1 thiolase D. melanogaster 74.3 463
NP_498915.1 Protein B0303.3 C. elegans 67.1 446
Other hits (2 of 35) [Show all]SpeciesId(%)Len(aa)
XP_002714567.1 PREDICTED: mitochondrial trifunctional protein, beta subunit O. cuniculus 97.3 474
XP_001918227.1 PREDICTED: trifunctional enzyme subunit beta, mitochondrial isoform 1 E. caballus 97.0 474

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; heart; testis; kidney; intestine; placenta; uterus; uncharacterized tissue; liver; lung; muscle; connective tissue; adrenal gland; skin; embryonic tissue; eye; mixed; blood; mammary gland; thymus; stomach; bone marrow; vascular; pharynx; prostate; mouth; ovary; spleen; pancreas; parathyroid; trachea; bone; nerve; esophagus; cervix; pituitary gland; thyroid; bladder; lymph; spinal cord; salivary gland; ascites; lymph node; umbilical cord; adipose tissue; larynx; ear; amniotic fluid
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 2
Map position: 2p23
UniSTS entry: Chr X DXS6970E
UniSTS entry: Chr 2 RH12545
UniSTS entry: Chr 2 A005T34
UniSTS entry: Chr 2 G20487
UniSTS entry: Chr 2 D2S1556E
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (13)

AK130072.1 Homo sapiens cDNA FLJ26562 fis, clone LNF04029, highly similar to Trifunctional enzyme beta subunit, mitochondrial precursor P
NM_000183.2 Homo sapiens hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit (HADHB), nuclear gene encoding mitochondrial protein, mRNA PA
BC066963.1 Homo sapiens hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), beta subunit, mRNA (cDNA clone MGC:87480 IMAGE:4796447), complete cds PA
BC014572.1 Homo sapiens hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), beta subunit, mRNA (cDNA clone MGC:22699 IMAGE:3960772), complete cds PA
BC017564.2 Homo sapiens hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), beta subunit, mRNA (cDNA clone MGC:1727 IMAGE:2988132), complete cds PA
AK314455.1 Homo sapiens cDNA, FLJ95256, Homo sapiens hydroxyacyl-Coenzyme Adehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme Ahydratase (trifunctional protein), beta subunit (HADHB), mRNA P
BC030824.1 Homo sapiens hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), beta subunit, mRNA (cDNA clone MGC:24827 IMAGE:4288635), complete cds PA
AK095278.1 Homo sapiens cDNA FLJ37959 fis, clone CTONG2009572, highly similar to TRIFUNCTONAL ENZYME BETA SUBUNIT, MITOCHONDRIAL PRECURSOR P
AK293142.1 Homo sapiens cDNA FLJ59448 complete cds, highly similar to Trifunctional enzyme subunit beta, mitochondrial precursor P
AK304455.1 Homo sapiens cDNA FLJ56214 complete cds, highly similar to Trifunctional enzyme subunit beta, mitochondrial precursor P
AK302322.1 Homo sapiens cDNA FLJ55769 complete cds, highly similar to Trifunctional enzyme subunit beta, mitochondrial precursor P
AF113209.1 Homo sapiens MSTP029 mRNA, complete cds PA
D16481.1 Homo sapiens mRNA for mitochondrial 3-ketoacyl-CoA thiolase beta-subunit of trifunctional protein, complete cds PA

EST sequences (10 of 1895) [Show all sequences]

AA973776.1 Clone IMAGE:1586514 uncharacterized tissue 3' read PA
R15179.1 Clone IMAGE:29367 brain 5' read
R17352.1 Clone IMAGE:32098 brain 5' read
AI003324.1 Clone IMAGE:1685273 brain 3' read PA
AI039905.1 Clone IMAGE:1657375 embryonic tissue 3' read
AI052594.1 Clone IMAGE:1674888 mixed 3' read A
AI057374.1 Clone IMAGE:1674581 mixed 3' read A
AI078173.1 Clone IMAGE:1675132 mixed 3' read PA
AI127799.1 Clone IMAGE:1711318 uterus 3' read A
AI141695.1 Clone IMAGE:1614276 uncharacterized tissue 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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