> Isoprenylcysteine carboxyl methyltransferase (ICMT)
NCBI UniGene banner graphic
PubMed Nucleotide Protein Genome Structure Popset Taxonomy
 Search
NCBI

UniGene
Homepage
FAQs
Help
Query Tips
Build Info
Library Browser
DDD
Download UniGene

Related Databases
Gene
HomoloGene
EST
SRA

NIH cDNA Projects
MGC | ZGC | XGC
Finding cDNAs
UGID:906435     UniGene Hs.515688     Homo sapiens (human)   ICMT Order cDNA clone, Links
Isoprenylcysteine carboxyl methyltransferase (ICMT)

Human protein-coding gene ICMT. Represented by 499 ESTs from 218 cDNA libraries. Corresponds to reference sequence NM_012405.3. [UniGene 906435 - Hs.515688]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_003891076.1 PREDICTED: protein-S-isoprenylcysteine O-methyltransferase P. anubis 100.0 283
XP_525166.2 PREDICTED: protein-S-isoprenylcysteine O-methyltransferase P. troglodytes 100.0 283
NP_036537.1 ICMT gene product H. sapiens 100.0 283
NP_598549.1 Icmt gene product M. musculus 97.2 283
NP_001081219.1 protein-S-isoprenylcysteine O-methyltransferase X. laevis 80.7 279
NP_001017618.1 icmt gene product D. rerio 72.4 283
NP_648623.1 isoprenylcysteine carboxylmethyltransferase, isoform A D. melanogaster 56.2 291
NP_568191.1 protein-S-isoprenylcysteine O-methyltransferase B A. thaliana 51.1 178
NP_491473.1 Protein F21F3.3 C. elegans 46.0 189
Other hits (2 of 43) [Show all]SpeciesId(%)Len(aa)
NP_001231410.1 ICMT gene product S. scrofa 98.6 283
XP_004014079.1 PREDICTED: protein-S-isoprenylcysteine O-methyltransferase, partial O. aries 98.3 237

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: lung; brain; mixed; skin; embryonic tissue; eye; placenta; uncharacterized tissue; intestine; uterus; pancreas; mouth; kidney; prostate; liver; ovary; bone; connective tissue; parathyroid; spleen; testis; thyroid; thymus; trachea; muscle; blood; cervix; heart; bone marrow; bladder; lymph; ascites; lymph node; mammary gland; pituitary gland; stomach; ear; vascular; pineal gland; larynx; adrenal gland
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 1
Map position: 1p36.21
UniSTS entry: Chr 1 SHGC-74149 [Map Viewer]
UniSTS entry: Chr 1 SHGC-74066 [Map Viewer]
UniSTS entry: Chr 1 RH64691
UniSTS entry: Chr 1 D10S16
UniSTS entry: Chr 1 D11S3114
UniSTS entry: Chr 1 GDB:631802
UniSTS entry: Chr 1 D15S1477
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (5)

NM_012405.3 Homo sapiens isoprenylcysteine carboxyl methyltransferase (ICMT), mRNA P
CR541711.1 Homo sapiens full open reading frame cDNA clone RZPDo834E1228D for gene ICMT, isoprenylcysteine carboxyl methyltransferase; complete cds, without stopcodon P
CR541671.1 Homo sapiens full open reading frame cDNA clone RZPDo834H1127D for gene ICMT, isoprenylcysteine carboxyl methyltransferase; complete cds, incl. stopcodon P
AF173157.1 Homo sapiens MSTP098 (MST098) mRNA, complete cds A
BC028168.1 Homo sapiens isoprenylcysteine carboxyl methyltransferase, mRNA (cDNA clone MGC:39955 IMAGE:5245125), complete cds PA

EST sequences (10 of 499) [Show all sequences]

AA973610.1 Clone IMAGE:1569356 lung 3' read A
AA975831.1 Clone IMAGE:1558288 lung 3' read A
AA977501.1 Clone IMAGE:1561069 mixed 3' read A
AA984028.1 Clone IMAGE:1585178 lung 3' read
AA989294.1 Clone IMAGE:1604761 lung 3' read
AA993003.1 Clone IMAGE:1622721 embryonic tissue 3' read
AI025832.1 Clone IMAGE:1646578 parathyroid 3' read A
AI039056.1 Clone IMAGE:1657845 embryonic tissue 3' read A
AI042436.1 Clone IMAGE:1665037 skin 3' read A
AI049936.1 Clone IMAGE:1700592 kidney 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
NLM | NIH | UniGene | Privacy Statement | Disclaimer | NCBI Help