> UPF1 regulator of nonsense transcripts homolog (yeast) (UPF1)
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UGID:906013     UniGene Hs.515266     Homo sapiens (human)   UPF1 Order cDNA clone, Links
UPF1 regulator of nonsense transcripts homolog (yeast) (UPF1)

Human protein-coding gene UPF1. Represented by 512 ESTs from 243 cDNA libraries. Corresponds to reference sequence NM_002911.3. [UniGene 906013 - Hs.515266]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_533868.2 PREDICTED: regulator of nonsense transcripts 1 C. lupus familiaris 100.0 1118
NP_002902.2 UPF1 gene product H. sapiens 100.0 1117
XP_002808229.1 PREDICTED: LOW QUALITY PROTEIN: regulator of nonsense transcripts 1-like M. mulatta 100.0 1045
XP_003915257.1 PREDICTED: regulator of nonsense transcripts 1, partial P. anubis 100.0 1040
XP_003480799.1 PREDICTED: regulator of nonsense transcripts 1-like S. scrofa 100.0 160
XP_002688572.1 PREDICTED: regulator of nonsense transcripts 1 B. taurus 99.9 1115
XP_001915294.1 PREDICTED: regulator of nonsense transcripts 1 E. caballus 99.7 1068
XP_003213341.1 PREDICTED: regulator of nonsense transcripts 1-like M. gallopavo 99.7 1037
XP_003340788.1 PREDICTED: LOW QUALITY PROTEIN: regulator of nonsense transcripts 1-like M. domestica 99.5 1121
XP_418237.3 PREDICTED: regulator of nonsense transcripts 1 G. gallus 99.5 1082
NP_001116301.1 Upf1 gene product M. musculus 99.5 1123
NP_001085862.1 MGC80941 protein X. laevis 99.2 1097
NP_998639.1 upf1 gene product D. rerio 97.9 1099
NP_572767.1 Upf1 D. melanogaster 79.4 998
NP_199512.2 Regulator of nonsense transcripts 1-like protein A. thaliana 72.9 1109
XP_961233.1 ATP-dependent helicase NAM7 N. crassa 68.8 955
XP_001701790.1 UPF1 protein C. reinhardtii 65.5 799
NP_013797.1 ATP-dependent RNA helicase NAM7 S. cerevisiae 63.2 842
NP_490829.1 Protein SMG-2 C. elegans 60.3 1055
Other hits (2 of 46) [Show all]SpeciesId(%)Len(aa)
XP_003752928.1 PREDICTED: regulator of nonsense transcripts 1-like isoform 2 R. norvegicus 99.5 1123
XP_512972.4 PREDICTED: regulator of nonsense transcripts 1 P. troglodytes 99.2 1002

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: testis; brain; placenta; uncharacterized tissue; skin; mixed; lung; embryonic tissue; uterus; thyroid; muscle; vascular; spleen; bone marrow; bladder; trachea; salivary gland; tonsil; ascites; lymph node; intestine; liver; pancreas; eye; connective tissue; blood; kidney; prostate; heart; mouth; mammary gland; thymus; cervix; stomach; lymph; larynx; bone; nerve; adipose tissue; ganglia; ovary
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 19
Map position: 19p13.2-p13.11
UniSTS entry: Chr 19 A006H36
UniSTS entry: Chr 19 RH36847
UniSTS entry: Chr 19 RH25427
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (9)

AF074016.1 Homo sapiens nonsense-mediated mRNA decay trans-acting factor mRNA, complete cds P
AK128727.1 Homo sapiens cDNA FLJ46894 fis, clone UTERU3019708, highly similar to Regulator of nonsense transcripts 1 P
AK125797.1 Homo sapiens cDNA FLJ43809 fis, clone TESTI4001176, moderately similar to Regulator of nonsense transcripts 1 P
NM_002911.3 Homo sapiens UPF1 regulator of nonsense transcripts homolog (yeast) (UPF1), mRNA PA
BC034291.1 Homo sapiens UPF1 regulator of nonsense transcripts homolog (yeast), mRNA (cDNA clone IMAGE:4775809) A
U65533.1 Human regulator of nonsense transcript stability (RENT1) mRNA, complete cds PA
U59323.1 Human homolog of yeast UPF1 (HUPF1) mRNA, complete cds P
BC039817.1 Homo sapiens UPF1 regulator of nonsense transcripts homolog (yeast), mRNA (cDNA clone MGC:48687 IMAGE:5555509), complete cds PA
D86988.1 Homo sapiens mRNA for KIAA0221 gene, partial cds P

EST sequences (10 of 512) [Show all sequences]

AA862537.1 Clone IMAGE:1457039 kidney 3' read A
AA973404.1 Clone IMAGE:1569022 lung 3' read A
AA974710.1 Clone IMAGE:1578278 mixed 3' read A
AA976557.1 Clone IMAGE:1558647 lung 3' read A
AI003844.1 Clone IMAGE:1621721 testis 3' read A
AI052353.1 Clone IMAGE:1676030 mixed 3' read PA
AI080584.1 Clone IMAGE:1680419 skin 3' read A
AI129317.1 Clone IMAGE:1712809 uterus 3' read A
AI139605.1 Clone IMAGE:1735714 testis 3' read A
AI084436.1 Clone IMAGE:1662088 mixed 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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