> Mitogen-activated protein kinase kinase 3 (MAP2K3)
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UGID:904759     UniGene Hs.514012     Homo sapiens (human)   MAP2K3 Order cDNA clone, Links
Mitogen-activated protein kinase kinase 3 (MAP2K3)

Human protein-coding gene MAP2K3. Represented by 516 ESTs from 202 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 904759 - Hs.514012]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_001104193.1 PREDICTED: dual specificity mitogen-activated protein kinase kinase 3 isoform 3 M. mulatta 100.0 346
XP_003912520.1 PREDICTED: dual specificity mitogen-activated protein kinase kinase 3 isoform 1 P. anubis 100.0 346
XP_001150751.1 PREDICTED: dual specificity mitogen-activated protein kinase kinase 3 isoform 4 P. troglodytes 100.0 346
NP_659731.1 MAP2K3 gene product H. sapiens 100.0 346
XP_546666.2 PREDICTED: dual specificity mitogen-activated protein kinase kinase 3 C. lupus familiaris 100.0 346
NP_032954.1 Map2k3 gene product M. musculus 98.6 346
NP_001083843.1 MAP kinase activator XMEK3 X. laevis 89.5 334
NP_571799.1 map2k6 gene product D. rerio 87.2 350
NP_477162.1 licorne D. melanogaster 68.2 314
NP_509322.2 Protein SEK-1 C. elegans 57.1 329
XP_965727.2 hypothetical protein NCU00587 N. crassa 45.1 206
Other hits (2 of 46) [Show all]SpeciesId(%)Len(aa)
NP_001094144.1 Map2k3 gene product R. norvegicus 98.8 346
NP_001077162.1 MAP2K3 gene product B. taurus 98.8 346

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: lymph; skin; uncharacterized tissue; brain; heart; lung; bone marrow; trachea; mammary gland; ascites; kidney; blood; adrenal gland; intestine; esophagus; mixed; uterus; pancreas; thymus; mouth; spleen; connective tissue; bladder; tonsil; thyroid; placenta; embryonic tissue; vascular; liver; testis; lymph node; eye; prostate; stomach; muscle; salivary gland; cervix; nerve; bone; ovary; ganglia
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 17
Map position: 17q11.2
UniSTS entry: Chr 17 RH69047
UniSTS entry: Chr 17 MAP2K3_360
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (14)

NM_002756.4 Homo sapiens mitogen-activated protein kinase kinase 3 (MAP2K3), transcript variant A, mRNA P
CR536514.1 Homo sapiens full open reading frame cDNA clone RZPDo834D0920D for gene MAP2K3, mitogen-activated protein kinase kinase 3; complete cds, incl. stopcodon P
CR541793.1 Homo sapiens full open reading frame cDNA clone RZPDo834B0531D for gene MAP2K3, mitogen-activated protein kinase kinase 3; complete cds, without stopcodon P
AK223490.1 Homo sapiens mRNA for mitogen-activated protein kinase kinase 3 isoform B variant, clone: FCC119G12 P
L36719.1 Homo sapiens MAP kinase kinase 3 (MKK3) mRNA, complete cds P
AK315505.1 Homo sapiens cDNA, FLJ96569, Homo sapiens mitogen-activated protein kinase kinase 3 (MAP2K3),transcript variant B, mRNA P
BC032478.1 Homo sapiens mitogen-activated protein kinase kinase 3, mRNA (cDNA clone MGC:40348 IMAGE:5215093), complete cds PA
NM_145109.2 Homo sapiens mitogen-activated protein kinase kinase 3 (MAP2K3), transcript variant B, mRNA PA
AK093838.1 Homo sapiens cDNA FLJ36519 fis, clone TRACH2002092, highly similar to Dual specificity mitogen-activated proteinkinase kinase 3 (EC 2.7.12.2) P
AB451349.1 Homo sapiens MAP2K3 mRNA for mitogen-activated protein kinase kinase 3 isoform B, partial cds, clone: FLJ08011AAAF P
AB451226.1 Homo sapiens MAP2K3 mRNA for mitogen-activated protein kinase kinase 3 isoform B, complete cds, clone: FLJ08011AAAN P
GQ225578.1 Homo sapiens mitogen activated protein kinase kinase 3 (MAP2K3) mRNA, complete cds P
D87116.1 Homo sapiens mRNA for MAP kinase kinase 3b ,complete cds P
U66839.1 Human MAP kinase 3b mRNA, complete cds P

EST sequences (10 of 516) [Show all sequences]

R25570.1 Clone IMAGE:36542 brain 5' read
CB162913.1 Clone L18POOL1n1-41-H11 liver 5' read A
CB153446.1 Clone B1T694954-28-E02 brain 5' read P
CB144678.1 Clone L11SNU354s1-28-F02 liver 5' read P
AI239578.1 Clone IMAGE:1846830 mixed 3' read
AI243926.1 Clone IMAGE:1850815 mixed 3' read
AI343341.1 Clone IMAGE:2062047 intestine 3' read PA
AI371275.1 Clone IMAGE:1992858 uterus 3' read A
AI382176.1 Clone IMAGE:2092048 mixed 3' read
AI522141.1 Clone IMAGE:2138151 kidney 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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