> Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide (YWHAE)
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UGID:904598     UniGene Hs.513851     Homo sapiens (human)   YWHAE Order cDNA clone, Links
Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide (YWHAE)

Human protein-coding gene YWHAE. Represented by 2831 ESTs from 585 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 904598 - Hs.513851]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_033562.3 Ywhae gene product M. musculus 100.0 254
NP_001006219.1 YWHAE gene product G. gallus 100.0 254
XP_003912098.1 PREDICTED: 14-3-3 protein epsilon P. anubis 100.0 254
NP_006752.1 YWHAE gene product H. sapiens 100.0 254
XP_854358.1 PREDICTED: 14-3-3 protein epsilon isoform 2 C. lupus familiaris 100.0 254
XP_001504337.1 PREDICTED: 14-3-3 protein epsilon-like E. caballus 100.0 254
NP_776916.1 YWHAE gene product B. taurus 100.0 254
XP_002718936.1 PREDICTED: tyrosine 3/tryptophan 5 -monooxygenase activation protein, epsilon polypeptide O. cuniculus 100.0 254
XP_002196990.1 PREDICTED: tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide T. guttata 100.0 248
XP_004012588.1 PREDICTED: 14-3-3 protein epsilon O. aries 100.0 232
XP_001518912.2 PREDICTED: 14-3-3 protein epsilon-like O. anatinus 99.6 256
NP_113791.1 Ywhae gene product R. norvegicus 99.6 254
NP_997770.1 ywhae1 gene product D. rerio 98.8 254
NP_001080705.1 tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide X. laevis 98.8 254
NP_732312.1 14-3-3epsilon, isoform C D. melanogaster 91.4 255
NP_568557.1 14-3-3-like protein GF14 psi A. thaliana 83.9 254
XP_964462.1 14-3-3 protein 7 N. crassa 83.6 261
XP_001702812.1 14-3-3 protein C. reinhardtii 83.3 257
NP_010384.3 Bmh2p S. cerevisiae 81.0 268
NP_509939.1 Protein FTT-2, isoform a C. elegans 73.0 247
Other hits (2 of 57) [Show all]SpeciesId(%)Len(aa)
NP_001008156.1 ywhae gene product X. tropicalis 98.4 254
XP_003361720.1 PREDICTED: 14-3-3 protein epsilon-like S. scrofa 97.0 231

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; testis; lung; uterus; liver; uncharacterized tissue; embryonic tissue; intestine; kidney; eye; heart; placenta; skin; mammary gland; vascular; mixed; stomach; pancreas; prostate; ovary; blood; bone; muscle; ascites; connective tissue; mouth; cervix; lymph; salivary gland; bone marrow; esophagus; umbilical cord; thyroid; ganglia; thymus; lymph node; adrenal gland; pituitary gland; bladder; parathyroid; adipose tissue; pharynx; trachea; nerve; spleen; pineal gland; ear; amniotic fluid; spinal cord; larynx
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 17
Map position: 17p13.3
UniSTS entry: Chr 17 D17S1499E
UniSTS entry: RH70591
UniSTS entry: Chr 17 G19934
UniSTS entry: Chr 17 RH66862
UniSTS entry: Chr 17 STS-T60849 [Map Viewer]
UniSTS entry: Chr 17 RH104444
UniSTS entry: Chr 17 RH47135 [Map Viewer]
UniSTS entry: Chr 17 YWHAE__1220
UniSTS entry: Chr 3 WI-15464 [Map Viewer]
UniSTS entry: Chr 17 D17S1582
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (18)

BT007161.1 Homo sapiens tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide mRNA, complete cds P
AK128785.1 Homo sapiens cDNA FLJ45465 fis, clone BRSTN2012174, highly similar to 14-3-3 protein epsilon (14-3-3E) P
NM_006761.4 Homo sapiens tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide (YWHAE), transcript variant 1, mRNA PA
U28936.1 Human epsilon 14-3-3 protein mRNA, complete cds P
U43430.1 Human epsilon isoform 14-3-3 protein mRNA, complete cds PA
AY883089.1 Homo sapiens 14-3-3 protein epsilon isoform transcript variant 1 (YWHAE) mRNA, complete cds, alternatively spliced P
BC001440.2 Homo sapiens tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide, mRNA (cDNA clone MGC:1250 IMAGE:3139004), complete cds PA
BC000179.2 Homo sapiens tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide, mRNA (cDNA clone MGC:5005 IMAGE:2900956), complete cds PA
U43399.1 Human 14-3-3 protein epsilon isoform mRNA, complete cds P
AK296555.1 Homo sapiens cDNA FLJ53559 complete cds P
AK296050.1 Homo sapiens cDNA FLJ51975 complete cds, moderately similar to 14-3-3 protein epsilon (14-3-3E) P
AK295997.1 Homo sapiens cDNA FLJ60092 complete cds, highly similar to 14-3-3 protein epsilon (14-3-3E) P
AK295260.1 Homo sapiens cDNA FLJ51851 complete cds, highly similar to 14-3-3 protein epsilon (14-3-3E) P
U54778.1 Human 14-3-3 epsilon mRNA, complete cds P
AK316201.1 Homo sapiens cDNA, FLJ79100 complete cds, highly similar to 14-3-3 protein epsilon (14-3-3E) P
AK316185.1 Homo sapiens cDNA, FLJ79084 complete cds, highly similar to 14-3-3 protein epsilon (14-3-3E) P
NR_024058.1 Homo sapiens tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide (YWHAE), transcript variant 2, non-coding RNA PA
U20972.1 Human 14-3-3 protein epsilon isoform mRNA, complete cds P

EST sequences (10 of 2831) [Show all sequences]

AA962772.1 Clone IMAGE:1573440 kidney 3' read A
AA888157.1 Clone IMAGE:1492105 kidney 3' read A
AA969527.1 Clone IMAGE:1572970 kidney 3' read A
AA976438.1 Clone IMAGE:1589873 kidney 3' read A
AA989689.1 Clone IMAGE:1577579 spleen 3' read A
T05628.1 Clone HFBDD36 brain
AA995063.1 Clone IMAGE:1631570 mammary gland 3' read A
R16905.1 Clone IMAGE:129733 mixed 3' read A
AI002793.1 Clone IMAGE:1683782 brain 3' read
AI022838.1 Clone IMAGE:1650600 parathyroid 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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