> Retinoblastoma-like 2 (p130) (RBL2)
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UGID:904356     UniGene Hs.513609     Homo sapiens (human)   RBL2
Retinoblastoma-like 2 (p130) (RBL2)

Human protein-coding gene RBL2. Represented by 454 ESTs from 218 cDNA libraries. Corresponds to reference sequence NM_005611.3. [UniGene 904356 - Hs.513609]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_523371.2 PREDICTED: retinoblastoma-like protein 2 isoform 7 P. troglodytes 100.0 1138
NP_005602.3 RBL2 gene product H. sapiens 100.0 1138
XP_002802522.1 PREDICTED: retinoblastoma-like protein 2-like M. mulatta 99.7 1071
XP_003916920.1 PREDICTED: retinoblastoma-like protein 2 P. anubis 99.7 1138
NP_035380.3 Rbl2 gene product M. musculus 94.7 1134
XP_002667000.2 PREDICTED: retinoblastoma-like protein 2 D. rerio 72.1 1081
NP_001084880.1 retinoblastoma-like 1 (p107) X. laevis 55.7 997
Other hits (2 of 28) [Show all]SpeciesId(%)Len(aa)
XP_001492739.3 PREDICTED: retinoblastoma-like protein 2 E. caballus 98.8 1090
XP_535303.2 PREDICTED: retinoblastoma-like protein 2 isoform 1 C. lupus familiaris 98.5 1138

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: testis; brain; lung; uncharacterized tissue; mixed; placenta; thymus; lymph node; mammary gland; pharynx; kidney; uterus; embryonic tissue; skin; prostate; eye; thyroid; stomach; mouth; ovary; spleen; trachea; muscle; connective tissue; bladder; pancreas; vascular; blood; intestine; liver; bone marrow; bone; parathyroid; adrenal gland; heart; cervix; esophagus; larynx; salivary gland; ear; ascites; nerve; umbilical cord; adipose tissue
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 16
Map position: 16q12.2
UniSTS entry: Chr 16 RH65767
UniSTS entry: Chr 16 D16S2536E [Map Viewer]
UniSTS entry: Chr 16 G19455
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (11)

BX537767.1 Homo sapiens mRNA; cDNA DKFZp781K2028 (from clone DKFZp781K2028); complete cds PA
AK129969.1 Homo sapiens cDNA FLJ26459 fis, clone KDN03761, highly similar to Retinoblastoma-like protein 2 P
AK123139.1 Homo sapiens cDNA FLJ41144 fis, clone BRACE2036830
NM_005611.3 Homo sapiens retinoblastoma-like 2 (p130) (RBL2), mRNA PA
AK307881.1 Homo sapiens cDNA, FLJ97829 P
BC034490.1 Homo sapiens retinoblastoma-like 2 (p130), mRNA (cDNA clone MGC:26535 IMAGE:4838444), complete cds PA
AK300047.1 Homo sapiens cDNA FLJ53188 complete cds, highly similar to Retinoblastoma-like protein 2 P
AK304283.1 Homo sapiens cDNA FLJ53278 complete cds, highly similar to Retinoblastoma-like protein 2 P
X76061.1 H.sapiens p130 mRNA for 130K protein PA
X74594.1 H.sapiens mRNA for Rb2/p130 protein P
S67171.1 Rbr-2=retinoblastoma susceptibility gene [human, HeLa S3 suspension cells, mRNA, 3448 nt] P

EST sequences (10 of 454) [Show all sequences]

AA992582.1 Clone IMAGE:1624729 embryonic tissue 3' read P
AI005669.1 Clone IMAGE:1641625 testis 3' read A
AA927423.1 Clone IMAGE:1552507 uncharacterized tissue 3' read A
AI025340.1 Clone IMAGE:1643108 testis 3' read A
AI040434.1 Clone IMAGE:1646971 parathyroid 3' read A
R21714.1 Clone IMAGE:36209 brain 5' read P
BX109371.1 Clone IMAGp998D113104_;_IMAGE:1234138 lymph node P
AI193259.1 Clone IMAGE:1743014 lung 3' read A
CB105323.1 Clone L1HLK1-3-A04 liver 5' read
CB149026.1 Clone L15CKK1-39-B07 liver 5' read P


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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