> Branched chain ketoacid dehydrogenase kinase (BCKDK)
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UGID:904267     UniGene Hs.513520     Homo sapiens (human)   BCKDK Order cDNA clone, Links
Branched chain ketoacid dehydrogenase kinase (BCKDK)

Human protein-coding gene BCKDK. Represented by 595 ESTs from 256 cDNA libraries. Corresponds to 3 reference sequences (different isoforms). [UniGene 904267 - Hs.513520]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_001156688.1 PREDICTED: [3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial isoform 6 P. troglodytes 100.0 411
NP_005872.2 BCKDK gene product H. sapiens 100.0 411
NP_033869.1 Bckdk gene product M. musculus 98.3 411
NP_001085012.1 branched chain ketoacid dehydrogenase kinase X. laevis 89.3 402
NP_998225.1 bckdk gene product D. rerio 86.3 401
Other hits (2 of 21) [Show all]SpeciesId(%)Len(aa)
XP_001112186.1 PREDICTED: [3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial isoform 3 M. mulatta 99.3 411
XP_003916845.1 PREDICTED: [3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial P. anubis 99.3 411

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; testis; uncharacterized tissue; placenta; mixed; lung; skin; intestine; uterus; liver; eye; pancreas; embryonic tissue; kidney; muscle; heart; thyroid; prostate; mammary gland; adrenal gland; lymph node; larynx; umbilical cord; bladder; connective tissue; salivary gland; adipose tissue; ovary; cervix; mouth; blood; nerve; thymus; bone; spleen; stomach; vascular; lymph; esophagus; ascites; bone marrow
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 16
Map position: 16p11.2
UniSTS entry: Chr 16 SHGC-61092
UniSTS entry: RH48904
UniSTS entry: Chr 16 BCKDK_9086
UniSTS entry: Bckdk
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (9)

AK130145.1 Homo sapiens cDNA FLJ26635 fis, clone MPC07771, highly similar to [3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial precursor (EC 2.7.1.115) P
NM_005881.3 Homo sapiens branched chain ketoacid dehydrogenase kinase (BCKDK), nuclear gene encoding mitochondrial protein, transcript variant 1, mRNA PA
CR542093.1 Homo sapiens full open reading frame cDNA clone RZPDo834A0637D for gene BCKDK, branched chain alpha-ketoacid dehydrogenase kinase; complete cds, without stopcodon P
BC007363.2 Homo sapiens branched chain ketoacid dehydrogenase kinase, mRNA (cDNA clone MGC:16138 IMAGE:3630050), complete cds PA
BC009872.2 Homo sapiens branched chain ketoacid dehydrogenase kinase, mRNA (cDNA clone MGC:16430 IMAGE:3944953), complete cds PA
NM_001122957.2 Homo sapiens branched chain ketoacid dehydrogenase kinase (BCKDK), nuclear gene encoding mitochondrial protein, transcript variant 2, mRNA PA
AK294691.1 Homo sapiens cDNA FLJ60500 complete cds, highly similar to 3-methyl-2-oxobutanoate dehydrogenase (lipoamide) kinase (EC2.7.11.4) P
NM_001271926.1 Homo sapiens branched chain ketoacid dehydrogenase kinase (BCKDK), nuclear gene encoding mitochondrial protein, transcript variant 3, mRNA A
AF026548.1 Homo sapiens branched chain alpha-ketoacid dehydrogenase kinase precursor, mRNA, nuclear gene encoding mitochondrial protein, complete cds PA

EST sequences (10 of 595) [Show all sequences]

AA906488.1 Clone IMAGE:1506494 mixed 3' read A
AA970730.1 Clone IMAGE:1573106 kidney 3' read A
AA970731.1 Clone IMAGE:1573108 kidney 3' read A
AI021952.1 Clone IMAGE:1655432 mixed 3' read P
R19132.1 Clone IMAGE:33107 brain 5' read
AI091889.1 Clone IMAGE:1694216 heart 3' read A
AI129247.1 Clone IMAGE:1711876 uterus 3' read A
AI140015.1 Clone IMAGE:1691947 heart 3' read A
AI143747.1 Clone IMAGE:1705951 heart 3' read PA
CB045946.1 Clone IMAGE:3252560 kidney 3' read P


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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