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UGID:903805     UniGene Hs.513058     Homo sapiens (human)   TMED3
Transmembrane emp24 protein transport domain containing 3 (TMED3)

Human protein-coding gene TMED3. Represented by 601 ESTs from 282 cDNA libraries. Corresponds to reference sequence NM_007364.2. [UniGene 903805 - Hs.513058]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_001153825.1 PREDICTED: transmembrane emp24 domain-containing protein 3 isoform 2 P. troglodytes 100.0 216
NP_031390.1 TMED3 gene product H. sapiens 100.0 216
XP_001109063.1 PREDICTED: transmembrane emp24 domain-containing protein 3 M. mulatta 99.5 218
XP_003901330.1 PREDICTED: transmembrane emp24 domain-containing protein 3 P. anubis 99.5 218
NP_079636.2 Tmed3 gene product M. musculus 95.4 218
NP_998077.1 tmed7 gene product D. rerio 74.0 214
NP_001087434.1 transmembrane emp24 protein transport domain containing 7 precursor X. laevis 73.7 189
NP_491892.1 Protein F57B10.5 C. elegans 55.7 183
NP_572754.1 p24-related-1, isoform A D. melanogaster 52.4 187
Other hits (2 of 35) [Show all]SpeciesId(%)Len(aa)
NP_001004249.1 Tmed3 gene product R. norvegicus 97.7 220
NP_001191292.1 TMED3 gene product S. scrofa 97.2 215

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; lung; skin; pancreas; uncharacterized tissue; intestine; prostate; placenta; mixed; cervix; eye; liver; connective tissue; uterus; embryonic tissue; blood; testis; esophagus; parathyroid; stomach; bone; ovary; mammary gland; thyroid; adipose tissue; spleen; salivary gland; lymph; umbilical cord; epididymis; pharynx; lymph node; ear; vascular; ascites; heart; kidney; pituitary gland; tonsil; bone marrow; nerve; pineal gland; trachea; muscle
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 15
Map position: 15q24-q25
UniSTS entry: Chr 15 RH48894
UniSTS entry: Chr 15 RH1638 [Map Viewer]
UniSTS entry: Chr 15 A004H32 [Map Viewer]
UniSTS entry: Chr 15 RH78006
UniSTS entry: Chr 15 WI-15355 [Map Viewer]
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (16)

AJ132270.1 Homo sapiens mRNA for integral type I protein p24B (p26) P
AL109673.1 Homo sapiens mRNA full length insert cDNA clone EUROIMAGE 356973 PA
AL109672.1 Homo sapiens mRNA full length insert cDNA clone EUROIMAGE 755868 PA
AY358974.1 Homo sapiens clone DNA56052 P24B (UNQ535) mRNA, complete cds PA
NM_007364.2 Homo sapiens transmembrane emp24 protein transport domain containing 3 (TMED3), mRNA PA
CR457384.1 Homo sapiens full open reading frame cDNA clone RZPDo834H0410D for gene P24B, integral type I protein; complete cds, incl. stopcodon P
AK222516.1 Homo sapiens mRNA for chromosome 15 open reading frame 22 variant, clone: adKA03476 P
BC111547.1 Homo sapiens transmembrane emp24 protein transport domain containing 3, mRNA (cDNA clone MGC:133022 IMAGE:40005178), complete cds P
BC000027.2 Homo sapiens transmembrane emp24 protein transport domain containing 3, mRNA (cDNA clone MGC:1302 IMAGE:3507308), complete cds PA
BC010853.1 Homo sapiens transmembrane emp24 protein transport domain containing 3, mRNA (cDNA clone MGC:8938 IMAGE:3876465), complete cds PA
BC017495.1 Homo sapiens transmembrane emp24 protein transport domain containing 3, mRNA (cDNA clone MGC:17995 IMAGE:3921858), complete cds PA
BC022232.1 Homo sapiens transmembrane emp24 protein transport domain containing 3, mRNA (cDNA clone MGC:21508 IMAGE:3885305), complete cds PA
AK289434.1 Homo sapiens cDNA FLJ75946 complete cds, highly similar to Homo sapiens transmembrane emp24 protein transport domain containing 3 (TMED3), mRNA PA
AK297710.1 Homo sapiens cDNA FLJ58917 complete cds, highly similar to Transmembrane emp24 domain-containing protein 3 precursor P
AK304148.1 Homo sapiens cDNA FLJ58873 complete cds, highly similar to Transmembrane emp24 domain-containing protein 3 precursor P
AK075529.1 Homo sapiens cDNA PSEC0228 fis, clone HEMBA1006099, weakly similar to COP-COATED VESICLE MEMBRANE PROTEIN P24 PRECURSOR P

EST sequences (10 of 601) [Show all sequences]

AA960754.1 Clone IMAGE:1552162 uncharacterized tissue 3' read A
AA996207.1 Clone IMAGE:1604121 lung 3' read A
AI033711.1 Clone IMAGE:1648006 parathyroid 3' read
AI091913.1 Clone IMAGE:1694241 heart 3' read A
AI147744.1 Clone IMAGE:1703273 brain 3' read A
AI148291.1 Clone IMAGE:1680599 skin 3' read A
BX095484.1 Clone IMAGp998J121817_;_IMAGE:740075 ovary P
AI184246.1 Clone IMAGE:1714279 placenta 3' read A
R25915.1 Clone IMAGE:36745 brain 5' read
AI192578.1 Clone IMAGE:1743502 lung 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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