> SIN3 transcription regulator homolog A (yeast) (SIN3A)
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UGID:903786     UniGene Hs.513039     Homo sapiens (human)   SIN3A Order cDNA clone, Links
SIN3 transcription regulator homolog A (yeast) (SIN3A)

Human protein-coding gene SIN3A. Represented by 374 ESTs from 188 cDNA libraries. Corresponds to 3 reference sequences (different isoforms). [UniGene 903786 - Hs.513039]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_001102978.2 PREDICTED: paired amphipathic helix protein Sin3a-like isoform 1 M. mulatta 100.0 1272
XP_001142716.1 PREDICTED: paired amphipathic helix protein Sin3a isoform 8 P. troglodytes 100.0 1272
NP_001138829.1 SIN3A gene product H. sapiens 100.0 1272
XP_003918988.1 PREDICTED: paired amphipathic helix protein Sin3a-like, partial P. anubis 99.9 1153
XP_001491398.1 PREDICTED: paired amphipathic helix protein Sin3a E. caballus 99.7 1273
XP_003356722.1 PREDICTED: paired amphipathic helix protein Sin3a-like isoform 1 S. scrofa 99.7 1273
XP_535546.4 PREDICTED: paired amphipathic helix protein Sin3a C. lupus familiaris 99.6 1273
XP_002696677.1 PREDICTED: paired amphipathic helix protein Sin3a isoform 1 B. taurus 99.6 1273
XP_004017889.1 PREDICTED: paired amphipathic helix protein Sin3a O. aries 99.6 1273
NP_035508.2 Sin3a gene product M. musculus 99.1 1273
NP_001081937.1 SIN3 transcription regulator homolog A X. laevis 87.4 1274
NP_001091650.1 sin3aa gene product D. rerio 83.1 1275
NP_725189.1 Sin3A, isoform D D. melanogaster 59.1 857
NP_014639.1 Sin3p S. cerevisiae 49.0 204
XP_965709.2 hypothetical protein NCU02578 N. crassa 45.8 190
Other hits (2 of 41) [Show all]SpeciesId(%)Len(aa)
NP_001102231.1 paired amphipathic helix protein Sin3a R. norvegicus 99.2 1128
XP_002722089.1 PREDICTED: hypothetical protein O. cuniculus 98.4 1208

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; testis; uncharacterized tissue; mammary gland; embryonic tissue; placenta; vascular; kidney; pancreas; connective tissue; blood; thymus; bladder; prostate; amniotic fluid; spleen; trachea; thyroid; intestine; eye; uterus; lung; skin; mixed; bone marrow; mouth; lymph node; muscle; ovary; liver; lymph; salivary gland; heart; tonsil; ascites; pharynx; cervix; parathyroid; bone
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 15
Map position: 15q24.2
UniSTS entry: Chr 15 RH101985
UniSTS entry: Chr 15 D15S735E
UniSTS entry: Chr 15 SIN3A_8019
UniSTS entry: Chr 15 RH44902
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (18)

BC052275.1 Homo sapiens SIN3 homolog A, transcription regulator (yeast), mRNA (cDNA clone IMAGE:4565171) PA
AL117513.1 Homo sapiens mRNA; cDNA DKFZp434K2235 (from clone DKFZp434K2235); partial cds PA
AF418569.1 Homo sapiens MSIN3A mRNA, complete cds PA
BX649162.1 Homo sapiens mRNA; cDNA DKFZp686N1529 (from clone DKFZp686N1529) PA
BC018973.1 Homo sapiens SIN3 homolog A, transcription regulator (yeast), mRNA (cDNA clone IMAGE:3604034), partial cds PA
BC137099.1 Homo sapiens SIN3 homolog A, transcription regulator (yeast), mRNA (cDNA clone MGC:168719 IMAGE:9021096), complete cds P
BC137098.1 Homo sapiens SIN3 homolog A, transcription regulator (yeast), mRNA (cDNA clone MGC:168718 IMAGE:9021095), complete cds P
AL832463.1 Homo sapiens mRNA; cDNA DKFZp313F111 (from clone DKFZp313F111) PA
AK074903.1 Homo sapiens cDNA FLJ90422 fis, clone NT2RP3000378, weakly similar to PAIRED AMPHIPATHIC HELIX PROTEIN P
AK074800.1 Homo sapiens cDNA FLJ90319 fis, clone NT2RP2001538, highly similar to Paired amphipathic helix protein Sin3a P
AK027559.1 Homo sapiens cDNA FLJ14653 fis, clone NT2RP2002252, highly similar to Mus musculus (clone pVZmSin3A9) mSin3A9 mRNA P
AK096477.1 Homo sapiens cDNA FLJ39158 fis, clone OCBBF2002086, highly similar to Transcriptional regulator, SIN3A P
BC030563.1 Homo sapiens SIN3 homolog A, transcription regulator (yeast), mRNA (cDNA clone IMAGE:4471026), with apparent retained intron PA
AY044430.1 Homo sapiens transcriptional co-repressor Sin3A mRNA, partial cds P
NM_001145358.1 Homo sapiens SIN3 transcription regulator homolog A (yeast) (SIN3A), transcript variant 1, mRNA P
NM_001145357.1 Homo sapiens SIN3 transcription regulator homolog A (yeast) (SIN3A), transcript variant 3, mRNA P
NM_015477.2 Homo sapiens SIN3 transcription regulator homolog A (yeast) (SIN3A), transcript variant 2, mRNA P
BC041047.1 Homo sapiens SIN3 homolog A, transcription regulator (yeast), mRNA (cDNA clone IMAGE:4905696), with apparent retained intron PA

EST sequences (10 of 374) [Show all sequences]

AI018331.1 Clone IMAGE:1626863 mixed 3' read
R18944.1 Clone IMAGE:32983 brain 5' read
AI038103.1 Clone IMAGE:1647203 parathyroid 3' read
AI092971.1 Clone IMAGE:1692418 heart 3' read A
BX096938.1 Clone IMAGp998F08139_;_IMAGE:26455 brain A
BX098928.1 Clone IMAGp998C145347_;_IMAGE:2164933 brain
BX114720.1 Clone IMAGp998H17401_;_IMAGE:206656 mixed
R25817.1 Clone IMAGE:36386 brain 5' read
AI267904.1 Clone IMAGE:1909394 lung 3' read A
CB107976.1 Clone L3SNU475-15-E02 liver 5' read


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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