> Endothelin 1 (EDN1)
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UGID:902646     UniGene Hs.511899     Homo sapiens (human)   EDN1 Order cDNA clone, Links
Endothelin 1 (EDN1)

Human protein-coding gene EDN1. Represented by 170 ESTs from 89 cDNA libraries. EST representation biased toward neonate. Corresponds to 2 reference sequences (different isoforms). [UniGene 902646 - Hs.511899]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_001946.3 EDN1 gene product H. sapiens 100.0 211
NP_034234.1 Edn1 gene product M. musculus 78.7 201
NP_001121271.1 endothelin 1 precursor X. laevis 50.0 206
Other hits (2 of 16) [Show all]SpeciesId(%)Len(aa)
XP_518241.2 PREDICTED: endothelin-1 P. troglodytes 97.2 211
XP_001089874.1 PREDICTED: endothelin-1 M. mulatta 95.7 210

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
Restricted Expression: neonate [show more like this]
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; lung; mixed; placenta; vascular; liver; uncharacterized tissue; pharynx; kidney; skin; uterus; testis; heart; ovary; eye; esophagus; muscle; connective tissue; umbilical cord; intestine; stomach; embryonic tissue; pancreas; adipose tissue; bone; mammary gland
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 6
Map position: 6p24.1
UniSTS entry: Chr 6 WI-7563 [Map Viewer]
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (9)

NM_001955.4 Homo sapiens endothelin 1 (EDN1), transcript variant 1, mRNA PA
CR541903.1 Homo sapiens full open reading frame cDNA clone RZPDo834D1233D for gene EDN1, endothelin 1; complete cds, incl. stopcodon P
Y00749.1 Human mRNA for endothelin P
BC009720.1 Homo sapiens endothelin 1, mRNA (cDNA clone MGC:9513 IMAGE:3900704), complete cds PA
AK291838.1 Homo sapiens cDNA FLJ75736 complete cds, highly similar to Homo sapiens endothelin 1 (EDN1), mRNA P
AK313914.1 Homo sapiens cDNA, FLJ94552 P
AK307089.1 Homo sapiens cDNA, FLJ97037 P
NM_001168319.1 Homo sapiens endothelin 1 (EDN1), transcript variant 2, mRNA PA
S56805.1 preproendothelin 1 {alternatively transcribed} [human, placenta, mRNA, 1251 nt] P

EST sequences (10 of 170) [Show all sequences]

AI002660.1 Clone IMAGE:1629157 mixed 3' read
AA926633.1 Clone IMAGE:1542320 mixed 3' read
AI039852.1 Clone IMAGE:1664232 skin 3' read
AI094124.1 Clone IMAGE:1688631 mixed 3' read
AI095619.1 Clone IMAGE:1697193 uterus 3' read
AA907205.1 Clone IMAGE:1522393 lung 3' read A
AI126868.1 Clone IMAGE:1707829 heart 3' read
AI148215.1 Clone IMAGE:1681704 skin 3' read
BX098479.1 Clone IMAGp998G05124_;_IMAGE:125596 mixed P
AI167526.1 Clone IMAGE:1661335 mixed 3' read


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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