> Tubulin, beta 3 class III (TUBB3)
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UGID:902490     UniGene Hs.511743     Homo sapiens (human)   TUBB3
Tubulin, beta 3 class III (TUBB3)

Human protein-coding gene TUBB3. Represented by 1825 ESTs from 246 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 902490 - Hs.511743]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_075768.1 Tubb3 gene product M. musculus 100.0 449
NP_640347.2 Tubb3 gene product R. norvegicus 100.0 449
XP_001377872.2 PREDICTED: tubulin beta-3 chain-like M. domestica 100.0 449
XP_003315296.1 PREDICTED: tubulin beta-3 chain isoform 1 P. troglodytes 100.0 449
NP_006077.2 TUBB3 gene product H. sapiens 100.0 449
XP_003355769.2 PREDICTED: tubulin beta-3 chain-like S. scrofa 100.0 449
NP_001070595.1 TUBB3 gene product B. taurus 100.0 449
NP_001088455.1 tubulin, beta 3 class III X. laevis 100.0 448
NP_001026769.1 tubulin beta-4 chain G. gallus 100.0 448
XP_002723537.1 PREDICTED: tubulin, beta, 4-like O. cuniculus 99.8 451
NP_989408.1 tubb3 gene product X. tropicalis 99.8 448
NP_524290.2 beta-Tubulin at 85D D. melanogaster 96.0 445
NP_942104.2 tubb4b gene product D. rerio 95.9 443
NP_509585.1 Protein TBB-4 C. elegans 94.1 443
XP_001693997.1 beta tubulin 2 C. reinhardtii 88.0 442
XP_957669.2 tubulin beta chain N. crassa 87.4 446
NP_180515.1 tubulin beta A. thaliana 87.0 448
NP_116616.1 Tub2p S. cerevisiae 81.4 456
Other hits (2 of 61) [Show all]SpeciesId(%)Len(aa)
NP_001133764.1 Tubulin beta-3 chain S. salar 97.1 448
XP_003452462.1 PREDICTED: tubulin beta-5 chain-like O. niloticus 96.9 445

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; uncharacterized tissue; eye; lung; testis; embryonic tissue; skin; kidney; uterus; pancreas; mixed; bone marrow; ovary; connective tissue; liver; esophagus; prostate; cervix; blood; vascular; lymph node; nerve; salivary gland; thyroid; stomach; muscle; mammary gland; intestine; umbilical cord; epididymis; placenta; lymph; ganglia; heart; mouth; tonsil; bone; adrenal gland; pituitary gland; trachea
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 16
Map position: 16q24.3
UniSTS entry: Chr 16 RH65809 [Map Viewer]
UniSTS entry: Chr 6 RH65263 [Map Viewer]
UniSTS entry: Chr 16 PMC156124P3
UniSTS entry: Chr 16 SHGC-60611 [Map Viewer]
UniSTS entry: Chr 6 MARC_24021-24022:1029778648:1
UniSTS entry: Chr 1 GDB:312714
UniSTS entry: Tubb3
UniSTS entry: Chr 6 RH18135
UniSTS entry: Chr 6 Tubb2
UniSTS entry: Chr 6 IB1201 [Map Viewer]
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (17)

BC047518.1 Homo sapiens tubulin, beta 3, mRNA (cDNA clone IMAGE:5276469), partial cds P
AK127418.1 Homo sapiens cDNA FLJ45510 fis, clone BRTHA2020910, highly similar to Tubulin beta-4 chain P
AK122757.1 Homo sapiens cDNA FLJ16289 fis, clone OCBBF2009920, highly similar to TUBULIN BETA-3 CHAIN P
NM_006086.3 Homo sapiens tubulin, beta 3 class III (TUBB3), transcript variant 1, mRNA PA
AK223039.1 Homo sapiens mRNA for tubulin, beta, 4 variant, clone: JTH08432 PA
BC001678.2 Homo sapiens tubulin, beta 3, mRNA (cDNA clone IMAGE:2821278), partial cds PA
BC003021.1 Homo sapiens tubulin, beta 3, mRNA (cDNA clone MGC:4055 IMAGE:2823044), complete cds PA
BC000748.2 Homo sapiens tubulin, beta 3, mRNA (cDNA clone MGC:2411 IMAGE:2823044), complete cds PA
U47634.1 Human beta-tubulin class III isotype (beta-3) mRNA, complete cds P
AF427491.1 Homo sapiens class III beta tubulin mRNA, complete cds P
AK058140.1 Homo sapiens cDNA FLJ25411 fis, clone TST03333, highly similar to TUBULIN BETA-3 CHAIN P
BC020171.1 Homo sapiens cDNA clone IMAGE:3543976, **** WARNING: chimeric clone **** PA
AK292219.1 Homo sapiens cDNA FLJ77784 complete cds PA
AK314616.1 Homo sapiens cDNA, FLJ95457, highly similar to Homo sapiens tubulin, beta, 4 (TUBB4), mRNA P
AK307201.1 Homo sapiens cDNA, FLJ97149 P
S62643.1 beta-tubulin {EST} [human, mRNA Partial, 300 nt] P
NM_001197181.1 Homo sapiens tubulin, beta 3 class III (TUBB3), transcript variant 2, mRNA P

EST sequences (10 of 1825) [Show all sequences]

AA992317.1 Clone IMAGE:1620512 testis 3' read A
R19955.1 Clone IMAGE:34777 brain 5' read P
AI141702.1 Clone IMAGE:1614279 uncharacterized tissue 3' read PA
AI148209.1 Clone IMAGE:1680202 skin 3' read A
BX100915.1 Clone IMAGp998H11332_;_IMAGE:180154 brain
R25787.1 Clone IMAGE:36372 brain 5' read
CB126921.1 Clone L5HLK1s1-23-D10 liver 5' read P
CB121519.1 Clone L6ChoCK0-16-D07 liver 5' read P
CB152242.1 Clone B1T694954-15-B02 brain 5' read P
CB123584.1 Clone L12JSHC0-1-D10 liver 5' read P


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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