> Anterior pharynx defective 1 homolog B (C. elegans) (APH1B)
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UGID:726862     UniGene Hs.511703     Homo sapiens (human)   APH1B Order cDNA clone, Links
Anterior pharynx defective 1 homolog B (C. elegans) (APH1B)

Human protein-coding gene APH1B. Represented by 320 ESTs from 109 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 726862 - Hs.511703]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_523094.2 PREDICTED: uncharacterized protein LOC467700 isoform 2 P. troglodytes 100.0 256
NP_112591.2 APH1B gene product H. sapiens 100.0 256
NP_808251.1 Aph1b gene product M. musculus 87.5 256
NP_956409.1 aph1b gene product D. rerio 69.4 257
NP_001089056.1 anterior pharynx defective 1 homolog A X. laevis 59.5 246
NP_608710.1 anterior pharynx defective 1, isoform A D. melanogaster 50.2 225
Other hits (2 of 33) [Show all]SpeciesId(%)Len(aa)
XP_003901081.1 PREDICTED: gamma-secretase subunit APH-1B P. anubis 98.0 256
XP_001105067.1 PREDICTED: gamma-secretase subunit APH-1B M. mulatta 97.3 256

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: testis; brain; mixed; lung; eye; embryonic tissue; kidney; pancreas; placenta; prostate; adrenal gland; trachea; thymus; skin; thyroid; uncharacterized tissue; intestine; connective tissue; bone; blood; mammary gland; bone marrow; lymph node; uterus; liver; heart; bladder
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 15
Map position: 15q22.2
UniSTS entry: Chr 15 A007E02
UniSTS entry: Chr 15 STS-N31710 [Map Viewer]
UniSTS entry: Chr 15 D15S734E
UniSTS entry: RH65108
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (12)

AY358698.1 Homo sapiens clone DNA66658 TAAV688 (UNQ688) mRNA, complete cds P
AB189172.1 Homo sapiens APH-1b mRNA for anterior pharynx defective 1b short splicing variant, complete cds P
AL136671.1 Homo sapiens mRNA; cDNA DKFZp564D0372 (from clone DKFZp564D0372) PA
NM_031301.3 Homo sapiens anterior pharynx defective 1 homolog B (C. elegans) (APH1B), transcript variant 1, mRNA PA
AK057677.1 Homo sapiens cDNA FLJ33115 fis, clone TRACH2001314 A
BC020905.1 Homo sapiens anterior pharynx defective 1 homolog B (C. elegans), mRNA (cDNA clone MGC:24164 IMAGE:4720647), complete cds PA
AK291204.1 Homo sapiens cDNA FLJ75932 complete cds, highly similar to Homo sapiens anterior pharynx defective 1 homolog B (C. elegans) (APH1B), mRNA P
AK310843.1 Homo sapiens cDNA, FLJ17885 PA
AK307725.1 Homo sapiens cDNA, FLJ97673 P
AK307456.1 Homo sapiens cDNA, FLJ97404 P
NM_001145646.1 Homo sapiens anterior pharynx defective 1 homolog B (C. elegans) (APH1B), transcript variant 2, mRNA PA
AF508794.1 Homo sapiens presenilin stabilization factor-like protein (PSFL) mRNA, complete cds P

EST sequences (10 of 320) [Show all sequences]

AA976455.1 Clone IMAGE:1589895 kidney 3' read A
AI001990.1 Clone IMAGE:1619191 testis 3' read A
AI004282.1 Clone IMAGE:1626004 mixed 3' read PA
AI005113.1 Clone IMAGE:1626277 mixed 3' read PA
AI017128.1 Clone IMAGE:1639183 testis 3' read A
AI023997.1 Clone IMAGE:1652147 mixed 3' read A
AI079495.1 Clone IMAGE:1673592 mixed 3' read A
AI090930.1 Clone IMAGE:1690347 mixed 3' read A
AI126917.1 Clone IMAGE:1707890 heart 3' read A
AI143454.1 Clone IMAGE:1690682 mixed 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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