> Sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D (SEMA6D)
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UGID:726424     UniGene Hs.511265     Homo sapiens (human)   SEMA6D Order cDNA clone, Links
Sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D (SEMA6D)

Human protein-coding gene SEMA6D. Represented by 166 ESTs from 83 cDNA libraries. Corresponds to 7 reference sequences (different isoforms). [UniGene 726424 - Hs.511265]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_705871.1 SEMA6D gene product H. sapiens 100.0 1072
XP_523068.2 PREDICTED: semaphorin-6D isoform 11 P. troglodytes 99.9 1072
XP_001112236.1 PREDICTED: semaphorin-6D-like isoform 3 M. mulatta 99.8 1072
XP_003900940.1 PREDICTED: semaphorin-6D isoform 1 P. anubis 99.8 1010
NP_954711.1 Sema6d gene product M. musculus 97.5 1072
NP_001089133.1 sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D precursor X. laevis 85.0 1077
NP_001017682.2 sema6dl gene product D. rerio 80.0 1015
NP_611244.1 Sema-1b, isoform A D. melanogaster 54.7 247
Other hits (2 of 30) [Show all]SpeciesId(%)Len(aa)
XP_001502464.1 PREDICTED: semaphorin-6D isoform 1 E. caballus 99.2 1072
XP_004010688.1 PREDICTED: semaphorin-6D isoform 1 O. aries 99.0 1072

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; embryonic tissue; placenta; testis; kidney; ear; mammary gland; uterus; trachea; ganglia; mouth; eye; mixed; connective tissue; heart; pancreas; muscle; ovary; lung; vascular; intestine; skin; cervix; liver; thyroid
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 15
Map position: 15q21.1
UniSTS entry: Chr 15 D15S1223
UniSTS entry: Chr 15 D15S1188 [Map Viewer]
UniSTS entry: Chr 15 AFM205ye1
UniSTS entry: Chr 15 D15S123 [Map Viewer]
UniSTS entry: Chr 15 AB063027
UniSTS entry: Chr 15 SEMA6D_1632
UniSTS entry: Chr 15 G09531
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (19)

AB040912.2 Homo sapiens mRNA for KIAA1479 protein, partial cds P
AK021660.1 Homo sapiens cDNA FLJ11598 fis, clone HEMBA1003866, moderately similar to Mus musculus semaphorin VIa mRNA P
AK022747.1 Homo sapiens cDNA FLJ12685 fis, clone NT2RM4002493 P
AK022831.1 Homo sapiens cDNA FLJ12769 fis, clone NT2RP2001581 P
NM_024966.2 Homo sapiens sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D (SEMA6D), transcript variant 6, mRNA P
BC150253.1 Homo sapiens sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D, mRNA (cDNA clone MGC:166809 IMAGE:9007179), complete cds PA
AK290032.1 Homo sapiens cDNA FLJ78430 complete cds, highly similar to Homo sapiens sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D (SEMA6D), transcript variant 4, mRNA P
AF389430.1 Homo sapiens semaphorin 6D isoform 1 (SEMA6D) mRNA, complete cds; alternatively spliced PA
AF389429.1 Homo sapiens semaphorin 6D isoform 4 (SEMA6D) mRNA, complete cds; alternatively spliced PA
AF389428.1 Homo sapiens semaphorin 6D isoform 3 (SEMA6D) mRNA, complete cds; alternatively spliced PA
AF389427.1 Homo sapiens semaphorin 6D isoform 2 (SEMA6D) mRNA, complete cds; alternatively spliced PA
AF389426.1 Homo sapiens semaphorin 6D short isoform (SEMA6D) mRNA, complete cds; alternatively spliced P
BC004330.1 Homo sapiens cDNA clone IMAGE:3630507, containing frame-shift errors PA
NM_001198999.1 Homo sapiens sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D (SEMA6D), transcript variant 7, mRNA PA
NM_153619.1 Homo sapiens sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D (SEMA6D), transcript variant 5, mRNA PA
NM_153618.1 Homo sapiens sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D (SEMA6D), transcript variant 4, mRNA PA
NM_153617.1 Homo sapiens sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D (SEMA6D), transcript variant 3, mRNA PA
NM_153616.1 Homo sapiens sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D (SEMA6D), transcript variant 2, mRNA PA
NM_020858.1 Homo sapiens sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D (SEMA6D), transcript variant 1, mRNA PA

EST sequences (10 of 166) [Show all sequences]

AA988446.1 Clone IMAGE:1601903 lung 3' read
AI039185.1 Clone IMAGE:1657961 embryonic tissue 3' read
R20071.1 Clone IMAGE:35018 brain 5' read
R20462.1 Clone IMAGE:34452 brain 5' read
AI079213.1 Clone IMAGE:1669863 brain 3' read A
AI091457.1 Clone IMAGE:1566606 mixed 3' read
BX116638.1 Clone IMAGp998G22317_;_IMAGE:174381 brain
BX114180.1 Clone IMAGp998M05872_;_IMAGE:377260 heart
CB153332.1 Clone B1T694954-31-F07 brain 5' read
AI241292.1 Clone IMAGE:1869146 kidney 3' read


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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