> Serum/glucocorticoid regulated kinase 1 (SGK1)
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UGID:725237     UniGene Hs.510078     Homo sapiens (human)   SGK1 Order cDNA clone, Links
Serum/glucocorticoid regulated kinase 1 (SGK1)

Human protein-coding gene SGK1. Represented by 1592 ESTs from 366 cDNA libraries. Corresponds to 4 reference sequences (different isoforms). [UniGene 725237 - Hs.510078]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_001137148.1 SGK1 gene product H. sapiens 100.0 525
XP_001102277.2 PREDICTED: serine/threonine-protein kinase Sgk1-like isoform 1 M. mulatta 100.0 444
XP_003898204.1 PREDICTED: serine/threonine-protein kinase Sgk1 isoform 2 P. anubis 100.0 444
XP_003311548.1 PREDICTED: serine/threonine-protein kinase Sgk1 isoform 3 P. troglodytes 99.6 526
NP_001155317.2 Sgk1 gene product M. musculus 98.3 523
NP_001083809.1 serine/threonine-protein kinase Sgk1-A X. laevis 95.6 433
NP_954682.1 sgk1 gene product D. rerio 94.7 432
NP_001041298.1 Protein SGK-1, isoform a C. elegans 68.7 383
NP_732114.1 Akt1, isoform A D. melanogaster 60.7 323
XP_962134.2 serine/threonine-protein kinase gad8 N. crassa 60.3 335
NP_015121.1 Tpk2p S. cerevisiae 51.5 305
NP_187485.1 serine/threonine-protein kinase AtPK1/AtPK6 A. thaliana 50.6 243
XP_001699230.1 hypothetical protein CHLREDRAFT_121355 C. reinhardtii 48.0 244
Other hits (2 of 64) [Show all]SpeciesId(%)Len(aa)
NP_001075525.1 SGK1 gene product O. cuniculus 99.3 430
NP_001180497.1 Sgk1 gene product R. norvegicus 99.1 444

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; vascular; lung; blood; skin; uterus; kidney; testis; placenta; mixed; connective tissue; uncharacterized tissue; mouth; intestine; eye; liver; adrenal gland; parathyroid; thymus; pancreas; prostate; cervix; mammary gland; spleen; thyroid; stomach; trachea; muscle; nerve; pharynx; bladder; bone marrow; ear; ascites; ovary; larynx; esophagus; heart; bone; embryonic tissue; adipose tissue; lymph node; umbilical cord; epididymis; lymph; tonsil
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 6
Map position: 6q23
UniSTS entry: Chr 6 WI-13202 [Map Viewer]
UniSTS entry: Chr 6 STS-T33566 [Map Viewer]
UniSTS entry: Chr 6 RH102 [Map Viewer]
UniSTS entry: Chr 6 PMC86685P1
UniSTS entry: Chr 6 RH16308
UniSTS entry: Chr 6 MARC_12229-12230:1007996328:1
UniSTS entry: Chr 6 STS-H74007 [Map Viewer]
UniSTS entry: Chr 6 STS-H95353 [Map Viewer]
UniSTS entry: Chr 1 D7S3207
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (20)

BX537882.1 Homo sapiens mRNA; cDNA DKFZp686H1615 (from clone DKFZp686H1615) PA
NM_005627.3 Homo sapiens serum/glucocorticoid regulated kinase 1 (SGK1), transcript variant 1, mRNA PA
AF153609.1 Homo sapiens serine/threonine protein kinase sgk mRNA, complete cds PA
BC001263.1 Homo sapiens serum/glucocorticoid regulated kinase 1, mRNA (cDNA clone MGC:5030 IMAGE:3459056), complete cds PA
AK055077.1 Homo sapiens cDNA FLJ30515 fis, clone BRAWH2000686, highly similar to Serine/threonine-protein kinase Sgk1 (EC 2.7.11.1) P
AK098509.1 Homo sapiens cDNA FLJ25643 fis, clone STM07148, highly similar to SERINE/THREONINE-PROTEIN KINASE SGK (EC 2.7.1.-) P
BC013832.1 Homo sapiens serum/glucocorticoid regulated kinase 1, mRNA (cDNA clone IMAGE:4149746) A
FM205710.1 Homo sapiens mRNA for serum/glucocorticoid regulated kinase 1 variant F (SGK1 gene) P
FM205709.1 Homo sapiens mRNA for serum/glucocorticoid regulated kinase 1 variant D (SGK1 gene) P
FM205708.1 Homo sapiens mRNA for serum/glucocorticoid regulated kinase 1 variant C (SGK1 gene) P
FM205707.1 Homo sapiens mRNA for serum/glucocorticoid regulated kinase 1 variant B (SGK1 gene) PA
EU518415.1 Homo sapiens serum/glucocorticoid regulated kinase 1 isoform 2 (SGK1) mRNA, complete cds P
NM_001143678.1 Homo sapiens serum/glucocorticoid regulated kinase 1 (SGK1), transcript variant 4, mRNA PA
NM_001143677.1 Homo sapiens serum/glucocorticoid regulated kinase 1 (SGK1), transcript variant 3, mRNA PA
NM_001143676.1 Homo sapiens serum/glucocorticoid regulated kinase 1 (SGK1), transcript variant 2, mRNA PA
AK298688.1 Homo sapiens cDNA FLJ58680 complete cds, highly similar to Serine/threonine-protein kinase Sgk1 (EC 2.7.11.1) P
AK295422.1 Homo sapiens cDNA FLJ55062 complete cds, highly similar to Serine/threonine-protein kinase Sgk1 (EC 2.7.11.1) P
AK293383.1 Homo sapiens cDNA FLJ52914 complete cds, highly similar to Serine/threonine-protein kinase Sgk1 (EC 2.7.11.1) P
Y10032.1 H.sapiens mRNA for putative serine/threonine protein kinase PA
JQ836654.1 Homo sapiens Sgk1 variant i3 (SGK1) mRNA, partial cds

EST sequences (10 of 1592) [Show all sequences]

AA972807.1 Clone IMAGE:1578144 mixed 3' read A
R14910.1 Clone IMAGE:30214 brain 5' read P
R16898.1 Clone IMAGE:129728 mixed 3' read A
R16952.1 Clone IMAGE:129728 mixed 5' read
AA887418.1 Clone IMAGE:1501712 kidney 3' read P
AI027983.1 Clone IMAGE:1646091 parathyroid 3' read A
AI031765.1 Clone IMAGE:1649936 parathyroid 3' read
AI031934.1 Clone IMAGE:1650019 parathyroid 3' read A
AI032780.1 Clone IMAGE:1647066 parathyroid 3' read A
AI038125.1 Clone IMAGE:1647768 parathyroid 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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