> Cysteinyl-tRNA synthetase 2, mitochondrial (putative) (CARS2)
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UGID:723884     UniGene Hs.508725     Homo sapiens (human)   CARS2
Cysteinyl-tRNA synthetase 2, mitochondrial (putative) (CARS2)

Human protein-coding gene CARS2. Represented by 512 ESTs from 237 cDNA libraries. Corresponds to reference sequence NM_024537.2. [UniGene 723884 - Hs.508725]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_078813.1 CARS2 gene product H. sapiens 100.0 563
NP_077210.1 Cars2 gene product M. musculus 85.2 547
NP_001083370.1 probable cysteine--tRNA ligase, mitochondrial X. laevis 73.5 561
XP_682732.4 PREDICTED: cysteinyl-tRNA synthetase, mitochondrial D. rerio 70.7 543
NP_610930.1 CG8257 D. melanogaster 53.7 382
NP_014152.1 cysteine--tRNA ligase S. cerevisiae 52.9 289
NP_491014.1 Protein CARS-1, isoform b C. elegans 51.6 246
XP_001700207.1 cysteinyl-tRNA synthetase C. reinhardtii 50.4 280
XP_960203.2 hypothetical protein NCU05642 N. crassa 50.4 274
NP_198699.1 cysteinyl-tRNA synthetase A. thaliana 49.5 323
Other hits (2 of 62) [Show all]SpeciesId(%)Len(aa)
XP_509736.4 PREDICTED: probable cysteine--tRNA ligase, mitochondrial P. troglodytes 98.5 580
XP_001083935.1 PREDICTED: probable cysteinyl-tRNA synthetase, mitochondrial isoform 3 M. mulatta 97.7 562

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; testis; uncharacterized tissue; lung; skin; ovary; liver; placenta; mouth; mixed; eye; intestine; embryonic tissue; kidney; blood; uterus; prostate; pancreas; adrenal gland; pituitary gland; thymus; muscle; stomach; mammary gland; esophagus; thyroid; lymph; heart; vascular; connective tissue; spleen; ascites; pharynx; bone; cervix; nerve; adipose tissue; lymph node; parathyroid
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 13
Map position: 13q34
UniSTS entry: Chr 13 D13S675E
UniSTS entry: Chr 13 D13S1213E
UniSTS entry: Cars2
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (8)

BC042958.1 Homo sapiens cDNA clone IMAGE:5284550 A
BC082264.1 Homo sapiens cDNA clone IMAGE:6378727 A
AK022180.1 Homo sapiens cDNA FLJ12118 fis, clone MAMMA1000085, weakly similar to PUTATIVE CYSTEINYL-TRNA SYNTHETASE C29E6.06C (EC 6.1.1.16) P
NM_024537.2 Homo sapiens cysteinyl-tRNA synthetase 2, mitochondrial (putative) (CARS2), nuclear gene encoding mitochondrial protein, mRNA PA
BC007220.1 Homo sapiens cysteinyl-tRNA synthetase 2, mitochondrial (putative), mRNA (cDNA clone MGC:15044 IMAGE:2822557), complete cds PA
AB062436.1 Homo sapiens mRNA for OK/SW-CL.10, complete cds PA
AK301907.1 Homo sapiens cDNA FLJ58704 complete cds, weakly similar to Cysteinyl-tRNA synthetase (EC 6.1.1.16) P
BC041586.1 Homo sapiens cDNA clone IMAGE:4905026, partial cds A

EST sequences (10 of 512) [Show all sequences]

AA988815.1 Clone IMAGE:1602662 lung 3' read A
AI040844.1 Clone IMAGE:1647538 parathyroid 3' read
AI074253.1 Clone IMAGE:1682129 skin 3' read A
AI091536.1 Clone IMAGE:1567025 mixed 3' read PA
AA947302.1 Clone IMAGE:1508355 mixed 3' read
CB047094.1 Clone IMAGE:3253015 kidney 5' read PA
CB047093.1 Clone IMAGE:3253015 kidney 3' read A
AI086342.1 Clone IMAGE:1677896 mixed 3' read A
AI167312.1 Clone IMAGE:1661212 mixed 3' read A
BX112412.1 Clone IMAGp998M21206_;_IMAGE:140732 placenta A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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