> Doublecortin-like kinase 1 (DCLK1)
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UGID:722914     UniGene Hs.507755     Homo sapiens (human)   DCLK1 Order cDNA clone, Links
Doublecortin-like kinase 1 (DCLK1)

Human protein-coding gene DCLK1. Represented by 407 ESTs from 106 cDNA libraries. Corresponds to 4 reference sequences (different isoforms). [UniGene 722914 - Hs.507755]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_522657.3 PREDICTED: neuronal migration protein doublecortin isoform 4 P. troglodytes 100.0 728
NP_004725.1 DCLK1 gene product H. sapiens 100.0 728
XP_004012174.1 PREDICTED: serine/threonine-protein kinase DCLK1 isoform 4 O. aries 100.0 728
XP_003913810.1 PREDICTED: serine/threonine-protein kinase DCLK1-like isoform 1 P. anubis 100.0 432
XP_849124.2 PREDICTED: neuronal migration protein doublecortin isoform 2 C. lupus familiaris 100.0 432
NP_001182467.1 Dclk1 gene product M. musculus 98.8 739
NP_001139260.1 dclk2 gene product D. rerio 72.0 714
NP_001036461.1 CG17528, isoform B D. melanogaster 59.9 272
NP_001082643.1 pregnancy up-regulated non-ubiquitously expressed CaM kinase X. laevis 50.0 278
XP_959927.2 calcium/calmodulin-dependent protein kinase type I N. crassa 49.8 213
NP_500139.1 Protein CMK-1 C. elegans 48.1 283
NP_181383.2 CBL-interacting protein kinase 22 A. thaliana 47.1 157
Other hits (2 of 51) [Show all]SpeciesId(%)Len(aa)
XP_002720643.1 PREDICTED: doublecortin-like kinase 2 O. cuniculus 99.1 760
XP_001367866.1 PREDICTED: serine/threonine-protein kinase DCLK1 M. domestica 99.0 739

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; uncharacterized tissue; lung; embryonic tissue; testis; pituitary gland; mixed; kidney; trachea; eye; uterus; muscle; intestine; adipose tissue; spleen; ear; mammary gland; nerve; stomach; bone
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 13
Map position: 13q13
UniSTS entry: Chr 13 RH11210
UniSTS entry: Chr 13 WI-21179 [Map Viewer]
UniSTS entry: Chr 13 SHGC-56401
UniSTS entry: Chr 13 RH46169 [Map Viewer]
UniSTS entry: Chr 13 WI-14261 [Map Viewer]
UniSTS entry: Chr 13 RH44747 [Map Viewer]
UniSTS entry: Chr 13 SHGC-105091
UniSTS entry: Chr 13 DCAMKL1_4674
UniSTS entry: Chr 1 D11S2921
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (19)

AF052152.1 Homo sapiens clone 24628 mRNA sequence A
AF070534.1 Homo sapiens clones 24632 and 24634 mRNA sequence A
AK123427.1 Homo sapiens cDNA FLJ41433 fis, clone BRHIP2007307
NM_004734.4 Homo sapiens doublecortin-like kinase 1 (DCLK1), transcript variant 1, mRNA PA
CR627093.1 Homo sapiens mRNA; cDNA DKFZp686M19161 (from clone DKFZp686M19161) A
BC152456.1 Homo sapiens doublecortin-like kinase 1, mRNA (cDNA clone MGC:176710 IMAGE:8862589), complete cds PA
AK308925.1 Homo sapiens cDNA, FLJ98966 P
AK311459.1 Homo sapiens cDNA, FLJ18501
AK311438.1 Homo sapiens cDNA, FLJ18480 P
AK311434.1 Homo sapiens cDNA, FLJ18476 P
AK311195.1 Homo sapiens cDNA, FLJ18237 P
AK311183.1 Homo sapiens cDNA, FLJ18225 P
AK299829.1 Homo sapiens cDNA FLJ51726 complete cds, highly similar to Serine/threonine-protein kinase DCAMKL1 (EC 2.7.11.1) PA
AK299059.1 Homo sapiens cDNA FLJ50623 complete cds, highly similar to Serine/threonine-protein kinase DCAMKL1 (EC 2.7.11.1) P
AK295777.1 Homo sapiens cDNA FLJ50539 complete cds, highly similar to Homo sapiens doublecortin and CaM kinase-like 1 (DCAMKL1), mRNA P
NM_001195430.1 Homo sapiens doublecortin-like kinase 1 (DCLK1), transcript variant 4, mRNA
NM_001195416.1 Homo sapiens doublecortin-like kinase 1 (DCLK1), transcript variant 3, mRNA P
NM_001195415.1 Homo sapiens doublecortin-like kinase 1 (DCLK1), transcript variant 2, mRNA P
AB002367.1 Homo sapiens mRNA for KIAA0369 gene, partial cds P

EST sequences (10 of 407) [Show all sequences]

AA984223.1 Clone IMAGE:1629635 brain 3' read
AA885845.1 Clone IMAGE:1500377 lung 3' read A
AA887525.1 Clone IMAGE:1500532 lung 3' read A
AI039353.1 Clone IMAGE:1658433 embryonic tissue 3' read A
AI078603.1 Clone IMAGE:1678724 mixed 3' read
AI082666.1 Clone IMAGE:1660589 mixed 3' read A
AI088788.1 Clone IMAGE:1687402 brain 3' read A
AI097575.1 Clone IMAGE:1703112 brain 3' read A
AI129626.1 Clone IMAGE:1712910 uterus 3' read A
BX095750.1 Clone IMAGp998I183797_;_IMAGE:1500377 lung A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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