> SH2B adaptor protein 3 (SH2B3)
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UGID:721943     UniGene Hs.506784     Homo sapiens (human)   SH2B3 Order cDNA clone, Links
SH2B adaptor protein 3 (SH2B3)

Human protein-coding gene SH2B3. Represented by 266 ESTs from 157 cDNA libraries. Corresponds to reference sequence NM_005475.2. [UniGene 721943 - Hs.506784]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_005466.1 SH2B3 gene product H. sapiens 100.0 574
NP_032533.1 Sh2b3 gene product M. musculus 81.1 539
XP_003198643.1 PREDICTED: SH2B adapter protein 3 D. rerio 58.4 425
Other hits (2 of 21) [Show all]SpeciesId(%)Len(aa)
XP_509372.3 PREDICTED: SH2B adapter protein 3 isoform 2 P. troglodytes 99.5 575
XP_001108790.1 PREDICTED: SH2B adapter protein 3-like M. mulatta 97.7 569

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: mixed; brain; skin; uncharacterized tissue; embryonic tissue; lung; vascular; testis; muscle; spleen; uterus; lymph node; liver; mammary gland; eye; connective tissue; placenta; trachea; thymus; blood; nerve; bone; cervix; pancreas; intestine; kidney; heart; thyroid; ovary; mouth; lymph; salivary gland; bone marrow
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 12
Map position: 12q24
UniSTS entry: Chr 12 RH15682 [Map Viewer]
UniSTS entry: Chr 12 D12S2142
UniSTS entry: Chr 12 RH44606 [Map Viewer]
UniSTS entry: Chr 12 SGC35065 [Map Viewer]
UniSTS entry: Chr 12 WI-20633 [Map Viewer]
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (10)

AF055581.1 Homo sapiens adaptor protein Lnk mRNA, complete cds PA
AJ012793.1 Homo sapiens mRNA for lymphocyte adaptor protein (Lnk) P
NM_005475.2 Homo sapiens SH2B adaptor protein 3 (SH2B3), mRNA PA
AB208911.1 Homo sapiens mRNA for lymphocyte adaptor protein variant protein P
AK025666.1 Homo sapiens cDNA: FLJ22013 fis, clone HEP07283, highly similar to AF055581 Homo sapiens adaptor protein Lnk mRNA A
AK025745.1 Homo sapiens cDNA: FLJ22092 fis, clone HEP16534, highly similar to AF055581 Homo sapiens adaptor protein Lnk mRNA A
BC131575.1 Homo sapiens cDNA clone IMAGE:40109120 P
BC015786.1 Homo sapiens SH2B adaptor protein 3, mRNA (cDNA clone IMAGE:4861744), complete cds A
AK302173.1 Homo sapiens cDNA FLJ54917 complete cds, highly similar to Lymphocyte-specific adapter protein Lnk PA
BC136451.1 Homo sapiens SH2B adaptor protein 3, mRNA (cDNA clone MGC:168063 IMAGE:9020440), complete cds P

EST sequences (10 of 266) [Show all sequences]

AA969439.1 Clone IMAGE:1580585 mixed 3' read
AA985052.1 Clone IMAGE:1577307 spleen 3' read A
AA991323.1 Clone IMAGE:1606975 mammary gland 3' read A
AA993938.1 Clone IMAGE:1628839 mixed 3' read
AI018266.1 Clone IMAGE:1626783 mixed 3' read A
AI041105.1 Clone IMAGE:1641819 testis 3' read A
AI095048.1 Clone IMAGE:1686312 brain 3' read A
AI123859.1 Clone IMAGE:1692534 heart 3' read
CB052586.1 Clone IMAGE:3290363 uncharacterized tissue 5' read A
CB052585.1 Clone IMAGE:3290363 uncharacterized tissue 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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