> ISL LIM homeobox 1 (ISL1)
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UGID:130773     UniGene Hs.505     Homo sapiens (human)   ISL1 Order cDNA clone, Links
ISL LIM homeobox 1 (ISL1)

Human protein-coding gene ISL1. Represented by 81 ESTs from 45 cDNA libraries. Corresponds to reference sequence NM_002202.2. [UniGene 130773 - Hs.505]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_067434.3 Isl1 gene product M. musculus 100.0 348
NP_059035.3 Isl1 gene product R. norvegicus 100.0 348
XP_001365199.1 PREDICTED: insulin gene enhancer protein ISL-1-like M. domestica 100.0 348
XP_003899703.1 PREDICTED: insulin gene enhancer protein ISL-1 P. anubis 100.0 348
XP_001150633.2 PREDICTED: insulin gene enhancer protein ISL-1 isoform 2 P. troglodytes 100.0 348
NP_002193.2 ISL1 gene product H. sapiens 100.0 348
XP_853721.2 PREDICTED: insulin gene enhancer protein ISL-1 isoform 1 C. lupus familiaris 100.0 348
XP_001916580.1 PREDICTED: insulin gene enhancer protein ISL-1 E. caballus 100.0 348
XP_003133982.1 PREDICTED: insulin gene enhancer protein ISL-1-like S. scrofa 100.0 348
NP_001092600.1 ISL1 gene product B. taurus 100.0 348
XP_004017051.1 PREDICTED: insulin gene enhancer protein ISL-1 O. aries 100.0 348
XP_002714072.1 PREDICTED: islet-1 O. cuniculus 100.0 348
XP_002197098.1 PREDICTED: insulin gene enhancer protein ISL-1 T. guttata 99.7 348
NP_990745.1 ISL1 gene product G. gallus 99.7 348
NP_571037.1 isl1 gene product D. rerio 98.6 348
NP_001104188.1 ISL LIM homeobox 1 X. laevis 96.9 353
NP_476774.1 tailup, isoform B D. melanogaster 69.1 372
Other hits (2 of 23) [Show all]SpeciesId(%)Len(aa)
XP_001508080.2 PREDICTED: insulin gene enhancer protein ISL-1-like O. anatinus 99.2 359
XP_003216239.1 PREDICTED: insulin gene enhancer protein ISL-1-like A. carolinensis 98.8 348

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: eye; testis; embryonic tissue; uncharacterized tissue; pancreas; prostate; brain; lung; stomach; intestine; placenta; mixed; umbilical cord; kidney; muscle
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 5
Map position: 5q11.1
UniSTS entry: Chr 5 D5S2482
UniSTS entry: Chr 10 D10Bir8
UniSTS entry: Chr 5 D5S2482
UniSTS entry: Chr 5 ISL1__6479
UniSTS entry: Chr 5 GDB:383820
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (6)

NM_002202.2 Homo sapiens ISL LIM homeobox 1 (ISL1), mRNA PA
AK290742.1 Homo sapiens cDNA FLJ77081 complete cds, highly similar to Homo sapiens ISL1 transcription factor, LIM/homeodomain, (islet-1), mRNA P
BC031213.1 Homo sapiens ISL LIM homeobox 1, mRNA (cDNA clone MGC:39494 IMAGE:5269369), complete cds PA
BC017027.1 Homo sapiens ISL1 transcription factor, LIM/homeodomain, (islet-1), mRNA (cDNA clone IMAGE:3850052), containing frame-shift errors PA
U07559.1 Human ISL-1 (Islet-1) mRNA, complete cds P
S70721.1 isl-1=homeobox {LIM domain} [human, Choriocarcinoma JEG-3 cells, cervical carcinoma HeLa S3 cells, epidermoid carcinoma A-431 cells, mRNA, 1060 nt] P

EST sequences (10 of 81) [Show all sequences]

AA992221.1 Clone IMAGE:1618176 testis 3' read A
AA993442.1 Clone IMAGE:1618513 testis 3' read
AI147086.1 Clone IMAGE:1509638 mixed 3' read
BX112051.1 Clone IMAGp998B04883_;_IMAGE:381219 eye
AI277006.1 Clone IMAGE:1893032 placenta 3' read A
AI581396.1 Clone IMAGE:2183731 stomach 3' read
AI656372.1 Clone IMAGE:2243732 uncharacterized tissue 3' read A
CB243899.1 Clone UI-CF-FN0-agg-g-22-0-UI lung 3' read A
AI783715.1 Clone IMAGE:2252381 prostate 3' read A
AI784148.1 Clone IMAGE:2125742 mixed 3' read


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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