> Ubiquitin specific peptidase 28 (USP28)
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UGID:719050     UniGene Hs.503891     Homo sapiens (human)   USP28
Ubiquitin specific peptidase 28 (USP28)

Human protein-coding gene USP28. Represented by 150 ESTs from 95 cDNA libraries. EST representation biased toward blastocyst. Corresponds to reference sequence NM_020886.2. [UniGene 719050 - Hs.503891]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_065937.1 USP28 gene product H. sapiens 100.0 1076
XP_003313357.2 PREDICTED: LOW QUALITY PROTEIN: ubiquitin carboxyl-terminal hydrolase 28 P. troglodytes 99.8 1076
XP_001085291.1 PREDICTED: ubiquitin carboxyl-terminal hydrolase 28 isoform 1 M. mulatta 99.5 1076
NP_780691.2 ubiquitin carboxyl-terminal hydrolase 28 M. musculus 94.0 1050
NP_001001886.1 usp25 gene product D. rerio 61.0 1046
NP_001086746.1 ubiquitin specific peptidase 25 X. laevis 59.4 1022
Other hits (2 of 22) [Show all]SpeciesId(%)Len(aa)
XP_003910774.1 PREDICTED: ubiquitin carboxyl-terminal hydrolase 28-like P. anubis 99.3 827
XP_004016085.1 PREDICTED: ubiquitin carboxyl-terminal hydrolase 28 O. aries 96.5 923

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
Restricted Expression: blastocyst [show more like this]
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: uncharacterized tissue; heart; mouth; lung; testis; embryonic tissue; brain; bone marrow; prostate; liver; vascular; mixed; intestine; muscle; mammary gland; blood; kidney; bladder; trachea; cervix; uterus; placenta; salivary gland; lymph; skin; stomach; lymph node; eye; pancreas; pharynx; parathyroid; ovary
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 11
Map position: 11q23
UniSTS entry: Chr 1 D12S1332 [Map Viewer]
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (10)

AK123255.1 Homo sapiens cDNA FLJ41261 fis, clone BRAMY2034920
BC065928.1 Homo sapiens ubiquitin specific peptidase 28, mRNA (cDNA clone MGC:70638 IMAGE:6140725), complete cds PA
AB040948.1 Homo sapiens mRNA for KIAA1515 protein, partial cds P
AK027521.1 Homo sapiens cDNA FLJ14615 fis, clone NT2RP1001248 P
AF266283.1 Homo sapiens ubiquitin specific protease (USP28) mRNA, complete cds P
NM_020886.2 Homo sapiens ubiquitin specific peptidase 28 (USP28), mRNA PA
AK097623.1 Homo sapiens cDNA FLJ40304 fis, clone TESTI2029227, weakly similar to UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 21 (EC 3.1.2.15) P
AK304770.1 Homo sapiens cDNA FLJ58236 complete cds, highly similar to Ubiquitin carboxyl-terminal hydrolase 28 (EC 3.1.2.15) P
AK304376.1 Homo sapiens cDNA FLJ61554 complete cds, highly similar to Ubiquitin carboxyl-terminal hydrolase 28 (EC 3.1.2.15) P
BC035986.1 Homo sapiens ubiquitin specific peptidase 28, mRNA (cDNA clone IMAGE:4109294), with apparent retained intron PA

EST sequences (10 of 150) [Show all sequences]

AI026007.1 Clone IMAGE:1645748 parathyroid 3' read PA
AI337094.1 Clone IMAGE:2009559 uncharacterized tissue 3' read A
AI374954.1 Clone IMAGE:2048863 embryonic tissue 3' read
AI609285.1 Clone IMAGE:2266337 mouth 3' read A
AI659851.1 Clone IMAGE:2251444 prostate 3' read A
AI671626.1 Clone IMAGE:2308289 uncharacterized tissue 3' read A
BX282678.1 Clone IMAGp998K0313287_;_IMAGE:6044666 uncharacterized tissue P
AI818892.1 Clone IMAGE:2424763 uterus 3' read A
AI923030.1 Clone IMAGE:2452273 uterus 3' read PA
CB990391.1 Clone IMAGE:30340450 placenta 5' read P


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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