> Tight junction protein 2 (TJP2)
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UGID:137934     UniGene Hs.50382     Homo sapiens (human)   TJP2 Order cDNA clone, Links
Tight junction protein 2 (TJP2)

Human protein-coding gene TJP2. Represented by 602 ESTs from 244 cDNA libraries. Corresponds to 6 reference sequences (different isoforms). [UniGene 137934 - Hs.50382]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_001163887.1 TJP2 gene product H. sapiens 100.0 1220
XP_003312175.1 PREDICTED: tight junction protein ZO-2 isoform 1 P. troglodytes 99.8 1220
NP_001185914.1 Tjp2 gene product M. musculus 93.1 1189
NP_001188500.1 tjp2a gene product D. rerio 69.7 1197
NP_001090319.1 tight junction protein 2 X. laevis 68.0 410
NP_788603.1 polychaetoid, isoform F D. melanogaster 48.3 203
Other hits (2 of 31) [Show all]SpeciesId(%)Len(aa)
XP_003911833.1 PREDICTED: tight junction protein ZO-2 isoform 3 P. anubis 99.2 1218
XP_002808149.1 PREDICTED: LOW QUALITY PROTEIN: tight junction protein ZO-2-like M. mulatta 98.7 1193

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; testis; intestine; mixed; liver; lung; embryonic tissue; kidney; uncharacterized tissue; uterus; eye; thyroid; mammary gland; muscle; placenta; prostate; stomach; mouth; vascular; adrenal gland; connective tissue; thymus; spleen; umbilical cord; trachea; pancreas; bone; blood; lymph node; spinal cord; bladder; larynx; parathyroid; cervix; heart; ovary; pharynx; skin; ascites; nerve
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 9
Map position: 9q13-q21
UniSTS entry: Chr 9 G54053
UniSTS entry: Chr 9 SGC30152 [Map Viewer]
UniSTS entry: Chr 9 RH39762
UniSTS entry: Chr 9 D9S1716 [Map Viewer]
UniSTS entry: Chr 9 SHGC-34170 [Map Viewer]
UniSTS entry: Chr 9 SHGC-132518
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (19)

NM_004817.3 Homo sapiens tight junction protein 2 (TJP2), transcript variant 1, mRNA PA
NM_201629.3 Homo sapiens tight junction protein 2 (TJP2), transcript variant 2, mRNA PA
L27476.1 Human X104 mRNA, complete cds P
AK308564.1 Homo sapiens cDNA, FLJ98605 P
AK307697.1 Homo sapiens cDNA, FLJ97645 P
BC027592.1 Homo sapiens tight junction protein 2 (zona occludens 2), mRNA (cDNA clone MGC:26306 IMAGE:4839233), complete cds PA
AF489824.1 Homo sapiens tight junction protein 2 (TJP2) mRNA, complete cds; alternatively spliced PA
BC028426.1 Homo sapiens cDNA clone IMAGE:4820998, containing frame-shift errors PA
AF083893.1 Homo sapiens tight junction protein ZO-2 isoform C mRNA, partial cds P
AF083892.1 Homo sapiens tight junction protein ZO-2 isoform A mRNA, partial cds P
U84581.1 Human zonula occludens 2 protein mRNA, partial cds P
AK304447.1 Homo sapiens cDNA FLJ61560 complete cds, highly similar to Tight junction protein ZO-2 P
AK302483.1 Homo sapiens cDNA FLJ54712 complete cds, highly similar to Tight junction protein ZO-2 P
AK295034.1 Homo sapiens cDNA FLJ53324 complete cds, highly similar to Tight junction protein ZO-2 P
AK295016.1 Homo sapiens cDNA FLJ59510 complete cds, highly similar to Homo sapiens tight junction protein 2 (TJP2), transcript variant 2, mRNA P
NM_001170416.1 Homo sapiens tight junction protein 2 (TJP2), transcript variant 3, mRNA PA
NM_001170415.1 Homo sapiens tight junction protein 2 (TJP2), transcript variant 4, mRNA PA
NM_001170414.2 Homo sapiens tight junction protein 2 (TJP2), transcript variant 5, mRNA PA
NM_001170630.1 Homo sapiens tight junction protein 2 (TJP2), transcript variant 6, mRNA P

EST sequences (10 of 602) [Show all sequences]

AA910456.1 Clone IMAGE:1505616 mixed 3' read A
AA975869.1 Clone IMAGE:1555647 kidney 3' read
AA983761.1 Clone IMAGE:1580858 mixed 3' read A
AA991185.1 Clone IMAGE:1606312 kidney 3' read A
AI017800.1 Clone IMAGE:1635976 kidney 3' read A
AI026774.1 Clone IMAGE:1645278 testis 3' read A
AI056020.1 Clone IMAGE:1648543 parathyroid 3' read A
AI127353.1 Clone IMAGE:1708624 heart 3' read P
AI131541.1 Clone IMAGE:1706579 heart 3' read A
AI146277.1 Clone IMAGE:1707057 heart 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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