> ALG8, alpha-1,3-glucosyltransferase (ALG8)
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UGID:718527     UniGene Hs.503368     Homo sapiens (human)   ALG8
ALG8, alpha-1,3-glucosyltransferase (ALG8)

Human protein-coding gene ALG8. Represented by 394 ESTs from 186 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 718527 - Hs.503368]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_003313272.1 PREDICTED: probable dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase isoform 1 P. troglodytes 100.0 525
NP_076984.2 ALG8 gene product H. sapiens 100.0 525
NP_950200.2 Alg8 gene product M. musculus 93.2 525
NP_001084808.1 asparagine-linked glycosylation 8, alpha-1,3-glucosyltransferase homolog X. laevis 77.0 531
NP_001017647.1 alg8 gene product D. rerio 74.4 519
NP_572355.1 CG4542 D. melanogaster 59.4 506
NP_181994.5 alpha-1,3-glucosyltransferase A. thaliana 52.0 373
XP_001696729.1 glycosyl transferase, type ALG6, ALG8 C. reinhardtii 51.6 341
XP_956676.1 hypothetical protein NCU00163 N. crassa 50.6 415
NP_014710.1 dolichyl-P-Glc:Glc1Man(9)GlcNAc(2)-PP-dolichol alpha-1,3-glucosyltransferase S. cerevisiae 46.0 202
NP_001021940.2 Protein C08H9.3, isoform a C. elegans 45.8 214
Other hits (2 of 48) [Show all]SpeciesId(%)Len(aa)
XP_003910517.1 PREDICTED: probable dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase P. anubis 98.9 531
XP_001093123.2 PREDICTED: probable dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase isoform 4 M. mulatta 98.7 310

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: testis; brain; uncharacterized tissue; adrenal gland; kidney; connective tissue; prostate; umbilical cord; adipose tissue; uterus; embryonic tissue; skin; mixed; mammary gland; bladder; spleen; ovary; pharynx; muscle; vascular; blood; lung; heart; liver; intestine; placenta; stomach; eye; pancreas; thymus; bone marrow; salivary gland; esophagus; bone; larynx; cervix; lymph node
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 11
Map position: 11q14.1
UniSTS entry: Chr 11 STS-N35710
UniSTS entry: D11S2593
UniSTS entry: D11S2591
UniSTS entry: D11S2920
UniSTS entry: PMC92356P1
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (9)

NM_001007027.2 Homo sapiens ALG8, alpha-1,3-glucosyltransferase (ALG8), transcript variant 2, mRNA P
BC001133.2 Homo sapiens asparagine-linked glycosylation 8, alpha-1,3-glucosyltransferase homolog (S. cerevisiae), mRNA (cDNA clone MGC:2840 IMAGE:2966827), complete cds PA
NM_024079.4 Homo sapiens ALG8, alpha-1,3-glucosyltransferase (ALG8), transcript variant 1, mRNA P
AK309050.1 Homo sapiens cDNA, FLJ99091 P
AK098614.1 Homo sapiens cDNA FLJ25748 fis, clone TST06109, highly similar to Homo sapiens mRNA for putative glucosyltransferase P
AK075194.1 Homo sapiens cDNA FLJ90713 fis, clone PLACE1008315, highly similar to Probable dolichyl pyrophosphateGlc1Man9GlcNAc2 alpha-1,3-glucosyltransferase (EC 2.4.1.-) P
AK075184.1 Homo sapiens cDNA FLJ90703 fis, clone PLACE1007169, highly similar to Homo sapiens mRNA for putative glucosyltransferase P
BC017892.1 Homo sapiens cDNA clone IMAGE:4134120, containing frame-shift errors PA
AJ224875.1 Homo sapiens mRNA for putative glucosyltransferase, partial cds PA

EST sequences (10 of 394) [Show all sequences]

AA961046.1 Clone IMAGE:1578808 mixed 3' read PA
AI217895.1 Clone IMAGE:1753324 testis 3' read PA
AI221030.1 Clone IMAGE:1758990 placenta 3' read PA
AI221246.1 Clone IMAGE:1842055 mixed 3' read PA
CB155957.1 Clone L17N670205n1-1-F10 liver 5' read P
CB110529.1 Clone L5HLK1-5-H02 liver 5' read P
CB140673.1 Clone L15CKK1-18-E11 liver 5' read P
AI285231.1 Clone IMAGE:1873316 intestine 3' read PA
AI285269.1 Clone IMAGE:1874610 intestine 3' read PA
AI339010.1 Clone IMAGE:1934463 mixed 3' read PA


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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