> 7-dehydrocholesterol reductase (DHCR7)
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UGID:718293     UniGene Hs.503134     Homo sapiens (human)   DHCR7 Order cDNA clone, Links
7-dehydrocholesterol reductase (DHCR7)

Human protein-coding gene DHCR7. Represented by 734 ESTs from 254 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 718293 - Hs.503134]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_001174206.1 PREDICTED: 7-dehydrocholesterol reductase isoform 7 P. troglodytes 100.0 474
NP_001351.2 DHCR7 gene product H. sapiens 100.0 474
NP_031882.1 7-dehydrocholesterol reductase M. musculus 93.2 470
NP_001079586.1 7-dehydrocholesterol reductase X. laevis 84.3 471
NP_958487.1 dhcr7 gene product D. rerio 84.0 468
NP_001077693.1 7-dehydrocholesterol reductase A. thaliana 45.5 178
Other hits (2 of 34) [Show all]SpeciesId(%)Len(aa)
XP_003909457.1 PREDICTED: 7-dehydrocholesterol reductase isoform 1 P. anubis 99.2 474
NP_001187072.1 40S ribosomal protein S7 I. punctatus 94.3 88

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; testis; uncharacterized tissue; mixed; skin; esophagus; kidney; prostate; intestine; umbilical cord; mouth; vascular; bone marrow; embryonic tissue; larynx; adrenal gland; ascites; pancreas; liver; ovary; trachea; lymph; eye; lung; stomach; uterus; placenta; blood; cervix; mammary gland; connective tissue; thyroid; bladder; nerve; bone; spleen; lymph node; heart; thymus
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 11
Map position: 11q13.4
UniSTS entry: Chr 11 D10S2392 [Map Viewer]
UniSTS entry: Chr 11 G60282
UniSTS entry: Chr 11 WI-13500 [Map Viewer]
UniSTS entry: Chr 11 D11S3420
UniSTS entry: Chr 11 MARC_54881-54882:1155673275:1
UniSTS entry: Chr 11 WI-16597 [Map Viewer]
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (11)

AF062481.1 Homo sapiens 7-dehydrocholesterol reductase (DHCR7) mRNA, partial cds PA
AF067127.1 Homo sapiens 7-dehydrocholesterol reductase (DHCR7) mRNA, complete cds PA
AF096305.1 Homo sapiens sterol reductase SR-2 (DHCR7) mRNA, complete cds PA
NM_001360.2 Homo sapiens 7-dehydrocholesterol reductase (DHCR7), transcript variant 1, mRNA P
BC000054.2 Homo sapiens 7-dehydrocholesterol reductase, mRNA (cDNA clone MGC:1760 IMAGE:3507516), complete cds PA
AK289497.1 Homo sapiens cDNA FLJ77740 complete cds, highly similar to Homo sapiens 7-dehydrocholesterol reductase, mRNA P
AK312775.1 Homo sapiens cDNA, FLJ93191, Homo sapiens 7-dehydrocholesterol reductase (DHCR7), mRNA P
AK309625.1 Homo sapiens cDNA, FLJ99666 P
AK303881.1 Homo sapiens cDNA FLJ51181 complete cds, highly similar to 7-dehydrocholesterol reductase (EC 1.3.1.21) P
NM_001163817.1 Homo sapiens 7-dehydrocholesterol reductase (DHCR7), transcript variant 2, mRNA P
AF034544.1 Homo sapiens delta7-sterol reductase mRNA, complete cds PA

EST sequences (10 of 734) [Show all sequences]

AA970494.1 Clone IMAGE:1579294 mixed 3' read A
AI022413.1 Clone IMAGE:1652411 mixed 3' read A
AI026700.1 Clone IMAGE:1644121 testis 3' read
AI034087.1 Clone IMAGE:1656101 mixed 3' read A
AI042444.1 Clone IMAGE:1665776 skin 3' read
AA923356.1 Clone IMAGE:1526477 mixed 3' read A
BX091206.1 Clone IMAGp998L04273_;_IMAGE:46546 brain P
AI183635.1 Clone IMAGE:1751562 testis 3' read A
AI190356.1 Clone IMAGE:1731710 heart 3' read A
AI192049.1 Clone IMAGE:1738692 testis 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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