> Ras homolog family member C (RHOC)
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UGID:717818     UniGene Hs.502659     Homo sapiens (human)   RHOC Order cDNA clone, Links
Ras homolog family member C (RHOC)

Human protein-coding gene RHOC. Represented by 826 ESTs from 302 cDNA libraries. Corresponds to 3 reference sequences (different isoforms). [UniGene 717818 - Hs.502659]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_031510.2 Rhoc gene product M. musculus 100.0 192
NP_001099931.1 Rhoc gene product R. norvegicus 100.0 192
XP_003340456.1 PREDICTED: rho-related GTP-binding protein RhoC-like M. domestica 100.0 192
XP_003308367.1 PREDICTED: rho-related GTP-binding protein RhoC isoform 1 P. troglodytes 100.0 192
NP_001036143.1 RHOC gene product H. sapiens 100.0 192
XP_540336.2 PREDICTED: rho-related GTP-binding protein RhoC C. lupus familiaris 100.0 192
XP_001917277.2 PREDICTED: rho-related GTP-binding protein RhoC-like E. caballus 100.0 192
XP_003125894.1 PREDICTED: rho-related GTP-binding protein RhoC-like S. scrofa 100.0 192
NP_001039603.1 RHOC gene product B. taurus 100.0 192
XP_004002383.1 PREDICTED: rho-related GTP-binding protein RhoC O. aries 100.0 192
NP_001079639.1 ras homolog family member C X. laevis 98.5 192
NP_001002445.1 rhoad gene product D. rerio 97.4 192
NP_477098.1 Rho1, isoform A D. melanogaster 95.8 191
NP_502959.1 Protein RHO-1 C. elegans 95.3 191
NP_015491.1 Rho1p S. cerevisiae 81.2 201
XP_956761.2 GTP-binding protein RHO-1 protein N. crassa 80.8 192
NP_195228.1 Rac-like GTP-binding protein ARAC3 A. thaliana 58.1 190
Other hits (2 of 55) [Show all]SpeciesId(%)Len(aa)
XP_003963339.1 PREDICTED: rho-related GTP-binding protein RhoC-like T. rubripes 99.5 192
NP_001187623.1 rho-related gtp-binding protein rhoc I. punctatus 99.5 192

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; skin; testis; placenta; lung; embryonic tissue; intestine; prostate; mixed; eye; kidney; uterus; liver; mammary gland; pancreas; amniotic fluid; heart; connective tissue; thyroid; lymph; salivary gland; lymph node; bone; ascites; bone marrow; ovary; uncharacterized tissue; pharynx; cervix; stomach; muscle; parathyroid; adrenal gland; spleen; bladder; blood; vascular; nerve; mouth; umbilical cord; pituitary gland; adipose tissue; epididymis
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 1
Map position: 1p13.1
UniSTS entry: Chr 1 SHGC-75332 [Map Viewer]
UniSTS entry: Chr 1 SHGC-33509 [Map Viewer]
UniSTS entry: Chr 1 ARHC_2499
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (13)

NM_175744.4 Homo sapiens ras homolog family member C (RHOC), transcript variant 1, mRNA PA
BC052808.1 Homo sapiens ras homolog gene family, member C, mRNA (cDNA clone MGC:61427 IMAGE:6064555), complete cds PA
BX648784.1 Homo sapiens mRNA; cDNA DKFZp686F07165 (from clone DKFZp686F07165) PA
CR450360.1 Homo sapiens full open reading frame cDNA clone RZPDo834C073D for gene ARHC, ras homolog gene family, member C; complete cds; without stopcodon P
BT019448.1 Homo sapiens hypothetical protein MGC19531 mRNA, complete cds P
L25081.1 Homo sapiens GTPase (rhoC) mRNA, complete cds P
NM_001042679.1 Homo sapiens ras homolog family member C (RHOC), transcript variant 3, mRNA PA
NM_001042678.1 Homo sapiens ras homolog family member C (RHOC), transcript variant 2, mRNA PA
BC007245.1 Homo sapiens ras homolog gene family, member C, mRNA (cDNA clone MGC:15462 IMAGE:2966676), complete cds PA
BC009177.2 Homo sapiens ras homolog gene family, member C, mRNA (cDNA clone MGC:1448 IMAGE:2988783), complete cds PA
AF498972.1 Homo sapiens small GTP binding protein RhoC (ARHC) mRNA, complete cds P
AK094474.1 Homo sapiens cDNA FLJ37155 fis, clone BRACE2026131, highly similar to Rho-related GTP-binding protein RhoC precursor P
X06821.1 Human rhoC mRNA (clone 9) P

EST sequences (10 of 826) [Show all sequences]

AA954699.1 Clone IMAGE:1572842 kidney 3' read A
AA962111.1 Clone IMAGE:1600282 uncharacterized tissue 3' read A
AA970807.1 Clone IMAGE:1576507 intestine 3' read A
AA975107.1 Clone IMAGE:1555872 uncharacterized tissue 3' read
AI002119.1 Clone IMAGE:1638043 testis 3' read A
AA927491.1 Clone IMAGE:1552556 uncharacterized tissue 3' read A
AI022824.1 Clone IMAGE:1650776 parathyroid 3' read
AI023130.1 Clone IMAGE:1650564 parathyroid 3' read A
AI025439.1 Clone IMAGE:1648103 parathyroid 3' read A
AI026063.1 Clone IMAGE:1647273 parathyroid 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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