> CD44 molecule (Indian blood group) (CD44)
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UGID:717487     UniGene Hs.502328     Homo sapiens (human)   CD44
CD44 molecule (Indian blood group) (CD44)

Human protein-coding gene CD44. Represented by 2163 ESTs from 497 cDNA libraries. Corresponds to 8 reference sequences (different isoforms). [UniGene 717487 - Hs.502328]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_000601.3 CD44 gene product H. sapiens 100.0 741
NP_033981.2 Cd44 gene product M. musculus 78.7 779
Other hits (2 of 16) [Show all]SpeciesId(%)Len(aa)
XP_001152601.1 PREDICTED: CD44 antigen isoform 22 P. troglodytes 99.2 741
XP_003910086.1 PREDICTED: CD44 antigen isoform 1 P. anubis 97.4 492

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; uterus; lung; skin; vascular; connective tissue; kidney; uncharacterized tissue; mouth; pancreas; ascites; mammary gland; trachea; stomach; placenta; intestine; liver; mixed; esophagus; lymph node; eye; bladder; blood; prostate; testis; thymus; bone marrow; embryonic tissue; spleen; bone; muscle; tonsil; thyroid; cervix; pharynx; heart; ovary; larynx; salivary gland; ganglia; adrenal gland; amniotic fluid; adipose tissue; nerve; epididymis
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 11
Map position: 11p13
UniSTS entry: Chr 11 CD44
UniSTS entry: Chr 11 G62000
UniSTS entry: Chr 11 D11S4589
UniSTS entry: Chr 11 RH35975 [Map Viewer]
UniSTS entry: Chr 11 RH36176 [Map Viewer]
UniSTS entry: Chr 11 RH69895 [Map Viewer]
UniSTS entry: Chr 11 STS-N23307
UniSTS entry: GDB:185470
UniSTS entry: Chr 11 STS-H03494 [Map Viewer]
UniSTS entry: Chr 11 RH103158
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (44)

M25078.1 Human Hermes antigen gp90 homing receptor mRNA, 3' end P
AF098641.1 Homo sapiens CD44 isoform RC (CD44) mRNA, complete cds P
U94902.1 Human soluble CD44 (CD44) mRNA, with exon v9 extension, partial cds
U94903.1 Human soluble CD44 (CD44) mRNA, with exon v10 extension, partial cds
BC052287.1 Homo sapiens CD44 molecule (Indian blood group), mRNA (cDNA clone IMAGE:5428516), complete cds PA
AK129808.1 Homo sapiens cDNA FLJ26297 fis, clone DMC07218, highly similar to Homo sapiens CD44 antigen (homing function and Indian blood group system) (CD44) P
AK127622.1 Homo sapiens cDNA FLJ45720 fis, clone HCASM2000363
BC067348.1 Homo sapiens CD44 molecule (Indian blood group), mRNA (cDNA clone IMAGE:4842331), complete cds PA
M59040.1 Human cell adhesion molecule (CD44) mRNA, complete cds P
AJ251595.1 Homo sapiens mRNA for transmembrane glycoprotein (CD44 gene) P
NM_001001392.1 Homo sapiens CD44 molecule (Indian blood group) (CD44), transcript variant 5, mRNA PA
NM_001001391.1 Homo sapiens CD44 molecule (Indian blood group) (CD44), transcript variant 4, mRNA PA
NM_001001390.1 Homo sapiens CD44 molecule (Indian blood group) (CD44), transcript variant 3, mRNA PA
NM_001001389.1 Homo sapiens CD44 molecule (Indian blood group) (CD44), transcript variant 2, mRNA PA
AB073901.1 Homo sapiens primary neuroblastoma cDNA, clone:Nbla03779, full insert sequence
U40373.1 Human cell surface glycoprotein CD44 mRNA, complete cds PA
NM_000610.3 Homo sapiens CD44 molecule (Indian blood group) (CD44), transcript variant 1, mRNA PA
BC004372.1 Homo sapiens CD44 molecule (Indian blood group), mRNA (cDNA clone MGC:10468 IMAGE:3638681), complete cds PA
EF581837.1 Homo sapiens CD44 variant mRNA, complete cds, alternatively spliced P
AK290424.1 Homo sapiens cDNA FLJ76654 complete cds, highly similar to Homo sapiens CD44 antigen (homing function and Indian blood group system) (CD44), transcript variant 4, mRNA P
AK307707.1 Homo sapiens cDNA, FLJ97655 P
X56794.1 H.sapiens CD44R mRNA P
X55150.1 Human mRNA for CD44E (epithelial form) PA
AY101193.1 Homo sapiens CD44 antigen (CD44) mRNA, complete cds P
AY101192.1 Homo sapiens CD44 antigen (CD44) mRNA, complete cds P
AL832642.2 Homo sapiens mRNA; cDNA DKFZp451K1918 (from clone DKFZp451K1918); complete cds PA
X66733.1 H.sapiens mRNA for epican P
AK297776.1 Homo sapiens cDNA FLJ52702 complete cds, highly similar to Homo sapiens CD44 antigen (homing function and Indian blood group system) (CD44), transcript variant 4, mRNA P
AK304467.1 Homo sapiens cDNA FLJ60041 complete cds, highly similar to CD44 antigen precursor P
FJ216964.1 Homo sapiens CD44 mRNA, complete cds, alternatively spliced P
D28447.1 Homo sapiens mRNA for CD44 antigen, 5'UTR region
S82326.1 CD44=cell-cell and cell-matrix adhesion interaction glycoprotein isoform {alternatively spliced, exon 4-exon 13 junction region} [human, papillary thyroid carcinoma and contralateral thyroid tissue, thyroid carcinoma patient, mRNA Mutant, 530 nt] P
X55938.1 Human mRNA for CD44E core protein P
X62739.1 H.sapiens mRNA for variant CD44 P
M83328.1 Human cell surface glycoprotein CD44 mRNA, (variant F) exons 1, 2, 3, and 5 P
M83327.1 Human cell surface glycoprotein CD44 mRNA, (variant E) exons 1, 2, 3, and 4 P
M83326.1 Human cell surface glycoprotein CD44 mRNA, (variant D) exon 1, 2, and 3 P
M83325.1 Human cell surface glycoprotein CD44 mRNA, (variant C) exons 1 and 2 P
M83324.1 Human cell surface glycoprotein CD44 mRNA, (variant B) exon 1 P
S66400.1 CD44=CD44SP {alternatively spliced} [human, breast carcinoma cell line MCF-7, mRNA Partial, 1586 nt] P
NM_001202557.1 Homo sapiens CD44 molecule (Indian blood group) (CD44), transcript variant 8, mRNA P
NM_001202556.1 Homo sapiens CD44 molecule (Indian blood group) (CD44), transcript variant 7, mRNA PA
NM_001202555.1 Homo sapiens CD44 molecule (Indian blood group) (CD44), transcript variant 6, mRNA PA
M24915.1 Human CDw44 antigen, complete cds P

EST sequences (10 of 2163) [Show all sequences]

AA962536.1 Clone IMAGE:1602199 lung 3' read P
AA972695.1 Clone IMAGE:1584193 mixed 3' read PA
AA992549.1 Clone IMAGE:1623910 embryonic tissue 3' read A
AA907406.1 Clone IMAGE:1521760 lung 3' read A
AI024389.1 Clone IMAGE:1640913 testis 3' read A
AI032216.1 Clone IMAGE:1605595 kidney 3' read A
AI037851.1 Clone IMAGE:1664674 skin 3' read A
AI050741.1 Clone IMAGE:1663974 skin 3' read A
AI052595.1 Clone IMAGE:1674890 mixed 3' read P
AI081503.1 Clone IMAGE:1679093 skin 3' read P


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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