> DENN/MADD domain containing 5A (DENND5A)
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UGID:717016     UniGene Hs.501857     Homo sapiens (human)   DENND5A Order cDNA clone, Links
DENN/MADD domain containing 5A (DENND5A)

Human protein-coding gene DENND5A. Represented by 414 ESTs from 192 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 717016 - Hs.501857]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_056028.2 DENND5A gene product H. sapiens 100.0 1286
XP_508914.2 PREDICTED: DENN domain-containing protein 5A isoform 3 P. troglodytes 99.9 1286
XP_002799687.1 PREDICTED: DENN domain-containing protein 5A-like isoform 1 M. mulatta 99.9 1284
XP_534048.3 PREDICTED: DENN domain-containing protein 5A C. lupus familiaris 99.7 1284
XP_003910301.1 PREDICTED: LOW QUALITY PROTEIN: DENN domain-containing protein 5A P. anubis 99.6 1376
NP_067469.1 Dennd5a gene product M. musculus 99.0 1286
XP_001340162.4 PREDICTED: DENN domain-containing protein 5A D. rerio 89.2 1284
NP_647620.1 CG7852, isoform A D. melanogaster 53.7 1376
NP_495437.2 Protein LST-6 C. elegans 48.4 1049
Other hits (2 of 31) [Show all]SpeciesId(%)Len(aa)
XP_001252218.1 PREDICTED: DENN domain-containing protein 5A B. taurus 99.2 1284
XP_004016642.1 PREDICTED: DENN domain-containing protein 5A O. aries 99.1 1252

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; embryonic tissue; testis; placenta; thyroid; mammary gland; uterus; pharynx; stomach; intestine; mouth; kidney; eye; skin; heart; cervix; mixed; uncharacterized tissue; lung; muscle; lymph node; nerve; bone marrow; vascular; blood; liver; pancreas; thymus; ascites; salivary gland; bone; ovary; connective tissue; prostate; spleen; adipose tissue; ganglia
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 11
Map position: 11p15.4
UniSTS entry: Chr 11 RH18241 [Map Viewer]
UniSTS entry: Chr 11 WI-14657 [Map Viewer]
UniSTS entry: Chr 11 D11S4355 [Map Viewer]
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (14)

AB029014.1 Homo sapiens mRNA for KIAA1091 protein, partial cds P
AL117448.1 Homo sapiens mRNA; cDNA DKFZp586B1417 (from clone DKFZp586B1417) PA
AK125444.1 Homo sapiens cDNA FLJ43455 fis, clone OCBBF2035110, highly similar to Rab6-interacting protein 1 P
NM_015213.3 Homo sapiens DENN/MADD domain containing 5A (DENND5A), transcript variant 1, mRNA PA
BC071596.1 Homo sapiens DENN/MADD domain containing 5A, mRNA (cDNA clone MGC:87473 IMAGE:30348530), complete cds PA
AK025499.1 Homo sapiens cDNA: FLJ21846 fis, clone HEP01887 PA
AK026007.1 Homo sapiens cDNA: FLJ22354 fis, clone HRC06334 PA
BC009354.2 Homo sapiens DENN/MADD domain containing 5A, mRNA (cDNA clone IMAGE:4298580), partial cds PA
AK091148.1 Homo sapiens cDNA FLJ33829 fis, clone CTONG2003680 P
AK295881.1 Homo sapiens cDNA FLJ61286 complete cds, highly similar to Rab6-interacting protein 1 P
AK302478.1 Homo sapiens cDNA FLJ56807 complete cds, highly similar to Rab6-interacting protein 1 P
BC018797.1 Homo sapiens DENN/MADD domain containing 5A, mRNA (cDNA clone IMAGE:3357948) PA
BC005100.1 Homo sapiens cDNA clone IMAGE:3614189, containing frame-shift errors PA
NM_001243254.1 Homo sapiens DENN/MADD domain containing 5A (DENND5A), transcript variant 2, mRNA PA

EST sequences (10 of 414) [Show all sequences]

AA968438.1 Clone IMAGE:1580170 mixed 3' read A
AA922490.1 Clone IMAGE:1551558 uncharacterized tissue 3' read
AI091224.1 Clone IMAGE:1566929 mixed 3' read
AI093534.1 Clone IMAGE:1695704 uterus 3' read
R22764.1 Clone IMAGE:31437 brain 5' read P
AI139450.1 Clone IMAGE:1710177 heart 3' read
CB052835.1 Clone IMAGE:3290539 uncharacterized tissue 5' read
AI085615.1 Clone IMAGE:1678084 mixed 3' read PA
AI087184.1 Clone IMAGE:1679681 skin 3' read
AI208378.1 Clone IMAGE:1839253 testis 3' read


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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