> ADAM metallopeptidase domain 8 (ADAM8)
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UGID:716733     UniGene Hs.501574     Homo sapiens (human)   ADAM8 Order cDNA clone, Links
ADAM metallopeptidase domain 8 (ADAM8)

Human protein-coding gene ADAM8. Represented by 181 ESTs from 61 cDNA libraries. Corresponds to 3 reference sequences (different isoforms). [UniGene 716733 - Hs.501574]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_001100.3 ADAM8 gene product H. sapiens 100.0 823
NP_031429.1 disintegrin and metalloproteinase domain-containing protein 8 precursor M. musculus 69.7 824
NP_001124424.1 ADAM metallopeptidase domain 19 precursor X. laevis 52.7 368
NP_956931.1 adam8a gene product D. rerio 52.1 413
NP_996475.2 mind-meld, isoform B D. melanogaster 47.7 128
Other hits (2 of 30) [Show all]SpeciesId(%)Len(aa)
XP_003312884.1 PREDICTED: disintegrin and metalloproteinase domain-containing protein 8-like P. troglodytes 94.8 351
XP_003904486.1 PREDICTED: disintegrin and metalloproteinase domain-containing protein 8 isoform 1 P. anubis 94.4 823

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: thymus; blood; connective tissue; uncharacterized tissue; bone marrow; pancreas; spleen; thyroid; eye; intestine; placenta; brain; lung; cervix; kidney; larynx; trachea; mammary gland; stomach; testis; lymph node; uterus; mixed; esophagus; ascites; prostate
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 10
Map position: 10q26.3
UniSTS entry: Chr 10 RH80752
UniSTS entry: Chr 10 ADAM8_1412
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (10)

NM_001109.4 Homo sapiens ADAM metallopeptidase domain 8 (ADAM8), transcript variant 1, mRNA PA
BC064500.1 Homo sapiens ADAM metallopeptidase domain 8, mRNA (cDNA clone IMAGE:6247789) PA
BC115404.1 Homo sapiens ADAM metallopeptidase domain 8, mRNA (cDNA clone MGC:134985 IMAGE:40075505), complete cds P
AK310662.1 Homo sapiens cDNA, FLJ17704 P
AK312834.1 Homo sapiens cDNA, FLJ93272, highly similar to Homo sapiens a disintegrin and metalloproteinase domain 8 (ADAM8),mRNA P
AK301147.1 Homo sapiens cDNA FLJ50704 complete cds, highly similar to ADAM 8 precursor (EC 3.4.24.-) (A disintegrinand metalloproteinase domain 8) P
AK304324.1 Homo sapiens cDNA FLJ52194 complete cds, highly similar to ADAM 8 precursor (EC 3.4.24.-) (A disintegrinand metalloproteinase domain 8) P
NM_001164490.1 Homo sapiens ADAM metallopeptidase domain 8 (ADAM8), transcript variant 3, mRNA PA
NM_001164489.1 Homo sapiens ADAM metallopeptidase domain 8 (ADAM8), transcript variant 2, mRNA PA
D26579.1 Homo sapiens mRNA for transmembrane protein, complete cds P

EST sequences (10 of 181) [Show all sequences]

AI240862.1 Clone IMAGE:1867631 kidney 3' read P
AI282729.1 Clone IMAGE:1960147 esophagus 3' read P
AI368466.1 Clone IMAGE:2011485 brain 3' read P
AI422830.1 Clone IMAGE:2096991 brain 3' read P
AI479652.1 Clone IMAGE:2158334 uncharacterized tissue 3' read P
AI493443.1 Clone IMAGE:2116140 uncharacterized tissue 3' read A
AI569029.1 Clone IMAGE:2214400 lung 3' read P
AI583575.1 Clone IMAGE:2228697 pancreas 3' read A
AI686614.1 Clone IMAGE:2268641 uterus 3' read A
AI739529.1 Clone IMAGE:2391065 intestine 3' read P


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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