> TIA1 cytotoxic granule-associated RNA binding protein-like 1 (TIAL1)
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UGID:716362     UniGene Hs.501203     Homo sapiens (human)   TIAL1 Order cDNA clone, Links
TIA1 cytotoxic granule-associated RNA binding protein-like 1 (TIAL1)

Human protein-coding gene TIAL1. Represented by 531 ESTs from 260 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 716362 - Hs.501203]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_033409.1 Tial1 gene product M. musculus 100.0 391
NP_001013211.1 Tial1 gene product R. norvegicus 100.0 391
XP_003904380.1 PREDICTED: nucleolysin TIAR isoform 2 P. anubis 100.0 391
XP_001154768.1 PREDICTED: nucleolysin TIAR isoform 6 P. troglodytes 100.0 391
NP_001029097.1 TIAL1 gene product H. sapiens 100.0 391
XP_852319.1 PREDICTED: nucleolysin TIAR isoform 2 C. lupus familiaris 100.0 391
XP_003363459.1 PREDICTED: nucleolysin TIAR E. caballus 100.0 391
XP_003133244.1 PREDICTED: nucleolysin TIAR isoform 2 S. scrofa 100.0 391
XP_004020281.1 PREDICTED: nucleolysin TIAR isoform 2 O. aries 100.0 391
NP_001179985.1 nucleolysin TIAR B. taurus 100.0 379
XP_002718787.1 PREDICTED: TIA-1 related protein-like O. cuniculus 100.0 365
NP_957426.1 tial1 gene product D. rerio 92.4 369
NP_001087561.1 TIA1 cytotoxic granule-associated RNA binding protein X. laevis 83.5 387
NP_732942.1 Rox8, isoform B D. melanogaster 57.1 294
NP_495121.1 Protein TIAR-1, isoform a C. elegans 53.3 300
XP_962723.2 hypothetical protein NCU07874 N. crassa 46.5 170
NP_001117301.1 oligouridylate binding protein 1B A. thaliana 46.0 185
Other hits (2 of 41) [Show all]SpeciesId(%)Len(aa)
XP_001367857.1 PREDICTED: nucleolysin TIAR isoform 1 M. domestica 99.5 387
XP_002188262.1 PREDICTED: TIA1 cytotoxic granule-associated RNA binding protein-like 1 T. guttata 99.5 364

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; uncharacterized tissue; testis; lung; stomach; embryonic tissue; uterus; kidney; placenta; vascular; liver; mixed; intestine; pancreas; blood; mammary gland; muscle; adipose tissue; eye; parathyroid; heart; ear; bone; lymph; tonsil; prostate; bladder; salivary gland; connective tissue; ovary; lymph node; thymus; trachea; cervix; thyroid; skin; spleen; larynx; bone marrow; ascites; mouth; pituitary gland; adrenal gland; nerve
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 10
Map position: 10q
UniSTS entry: Chr 10 RH80809
UniSTS entry: Chr 10 RH81093
UniSTS entry: Chr 10 STS-N39410 [Map Viewer]
UniSTS entry: Chr 10 RH78958
UniSTS entry: Tial1
UniSTS entry: Chr 10 MARC_7529-7530:992008459:1
UniSTS entry: Chr 10 TIAL1_1101
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (15)

M96954.1 Homo sapiens nucleolysin TIAR mRNA, complete cds P
AK125264.1 Homo sapiens cDNA FLJ43274 fis, clone KIDNE2008914
NM_003252.3 Homo sapiens TIA1 cytotoxic granule-associated RNA binding protein-like 1 (TIAL1), transcript variant 1, mRNA P
AB209260.1 Homo sapiens mRNA for TIA1 cytotoxic granule-associated RNA-binding protein-like 1 isoform 2 variant protein P
NM_001033925.1 Homo sapiens TIA1 cytotoxic granule-associated RNA binding protein-like 1 (TIAL1), transcript variant 2, mRNA P
AY633610.1 Homo sapiens aging-associated gene 7 protein mRNA, complete cds P
BC128141.1 Homo sapiens TIA1 cytotoxic granule-associated RNA binding protein-like 1, mRNA (cDNA clone IMAGE:40112499), with apparent retained intron P
BC128140.1 Homo sapiens cDNA clone IMAGE:40112498, containing frame-shift errors P
AK291239.1 Homo sapiens cDNA FLJ76290 complete cds, highly similar to Homo sapiens TIA1 cytotoxic granule-associated RNA bindingprotein-like 1 (TIAL1), transcript variant 1, mRNA P
AK290984.1 Homo sapiens cDNA FLJ75459 complete cds P
AK290695.1 Homo sapiens cDNA FLJ78557 complete cds, highly similar to Homo sapiens TIA1 cytotoxic granule-associated RNA binding protein-like 1 (TIAL1), transcript variant 1, mRNA P
AL833106.1 Homo sapiens mRNA; cDNA DKFZp313P2115 (from clone DKFZp313P2115) PA
AK295243.1 Homo sapiens cDNA FLJ57984 complete cds, highly similar to Nucleolysin TIAR P
BC030025.1 Homo sapiens TIA1 cytotoxic granule-associated RNA binding protein-like 1, mRNA (cDNA clone MGC:33401 IMAGE:4821759), complete cds PA
D64015.1 Homo sapiens mRNA for T-cluster binding protein, complete cds P

EST sequences (10 of 531) [Show all sequences]

AA962329.1 Clone IMAGE:1569935 lung 3' read
AA972022.1 Clone IMAGE:1583674 mixed 3' read A
AA904846.1 Clone IMAGE:1504672 mixed 3' read A
AI057596.1 Clone IMAGE:1667433 parathyroid 3' read
AI061342.1 Clone IMAGE:1700794 kidney 3' read
AI061397.1 Clone IMAGE:1700100 kidney 3' read
AI088354.1 Clone IMAGE:1695560 uterus 3' read A
AI094901.1 Clone IMAGE:1686685 brain 3' read A
AI130686.1 Clone IMAGE:1709361 heart 3' read P
AI151317.1 Clone IMAGE:1715336 placenta 3' read P


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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