> Sphingosine-1-phosphate lyase 1 (SGPL1)
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UGID:715143     UniGene Hs.499984     Homo sapiens (human)   SGPL1 Order cDNA clone, Links
Sphingosine-1-phosphate lyase 1 (SGPL1)

Human protein-coding gene SGPL1. Represented by 334 ESTs from 190 cDNA libraries. Corresponds to reference sequence NM_003901.3. [UniGene 715143 - Hs.499984]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_003903866.1 PREDICTED: sphingosine-1-phosphate lyase 1 isoform 1 P. anubis 100.0 567
XP_521504.2 PREDICTED: sphingosine-1-phosphate lyase 1 isoform 6 P. troglodytes 100.0 567
NP_003892.2 SGPL1 gene product H. sapiens 100.0 567
XP_001106861.2 PREDICTED: sphingosine-1-phosphate lyase 1-like M. mulatta 100.0 561
NP_033189.2 Sgpl1 gene product M. musculus 88.4 567
NP_001091225.1 sphingosine-1-phosphate lyase 1 X. laevis 76.6 397
NP_001082938.1 sgpl1 gene product D. rerio 72.0 566
NP_652032.1 Sphingosine-1-phosphate lyase, isoform A D. melanogaster 55.9 517
NP_499913.1 Protein SPL-1 C. elegans 53.6 399
NP_174119.1 Sphingosine-1-phosphate lyase A. thaliana 52.9 349
XP_963533.1 sphingosine-1-phosphate lyase N. crassa 52.7 459
NP_010580.1 sphinganine-1-phosphate aldolase DPL1 S. cerevisiae 51.6 320
Other hits (2 of 56) [Show all]SpeciesId(%)Len(aa)
XP_001502842.1 PREDICTED: sphingosine-1-phosphate lyase 1 E. caballus 95.1 567
XP_546150.2 PREDICTED: sphingosine-1-phosphate lyase 1 C. lupus familiaris 94.0 567

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: uncharacterized tissue; brain; lung; uterus; lymph node; mouth; placenta; parathyroid; pancreas; mammary gland; kidney; ovary; intestine; testis; mixed; embryonic tissue; prostate; cervix; thyroid; blood; eye; liver; skin; vascular; thymus; trachea; larynx; bladder; heart; stomach; bone; connective tissue; pharynx; muscle; ascites; amniotic fluid; nerve; tonsil; lymph; adrenal gland
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 10
Map position: 10q21
UniSTS entry: Chr 10 WI-14267 [Map Viewer]
UniSTS entry: Chr 10 A009G12
UniSTS entry: Chr 10 G32525
UniSTS entry: Chr 10 SHGC-33649 [Map Viewer]
UniSTS entry: Chr 10 RH44692
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (12)

AJ011304.2 Homo sapiens mRNA for sphingosine-1-phosphate lyase P
BC051238.1 Homo sapiens sphingosine-1-phosphate lyase 1, mRNA (cDNA clone IMAGE:6253152), partial cds A
BC052991.1 Homo sapiens sphingosine-1-phosphate lyase 1, mRNA (cDNA clone MGC:60255 IMAGE:6150776), complete cds PA
BC068061.1 Homo sapiens cDNA clone IMAGE:6110411, partial cds A
AB033078.1 Homo sapiens mRNA for KIAA1252 protein, partial cds P
AF144638.1 Homo sapiens sphingosine-1-phosphate lyase (SPL) mRNA, complete cds P
AK023873.1 Homo sapiens cDNA FLJ13811 fis, clone THYRO1000320
NM_003901.3 Homo sapiens sphingosine-1-phosphate lyase 1 (SGPL1), mRNA PA
AK314615.1 Homo sapiens cDNA, FLJ95456, highly similar to Homo sapiens sphingosine-1-phosphate lyase 1 (SGPL1), mRNA P
AK308610.1 Homo sapiens cDNA, FLJ98651 P
BC031338.1 Homo sapiens sphingosine-1-phosphate lyase 1, mRNA (cDNA clone IMAGE:3658802), with apparent retained intron A
BC041567.1 Homo sapiens, clone IMAGE:3357509, mRNA A

EST sequences (10 of 334) [Show all sequences]

AA862531.1 Clone IMAGE:1457027 kidney 3' read A
AI042014.1 Clone IMAGE:1667769 parathyroid 3' read A
AI091626.1 Clone IMAGE:1682999 parathyroid 3' read A
AI128825.1 Clone IMAGE:1694415 heart 3' read P
CB051227.1 Clone IMAGE:3289312 prostate 3' read A
CB051228.1 Clone IMAGE:3289312 prostate 5' read
CB053542.1 Clone IMAGE:3290804 uncharacterized tissue 3' read A
CB053543.1 Clone IMAGE:3290804 uncharacterized tissue 5' read
BX092232.1 Clone IMAGp998E121793_;_IMAGE:730739 testis
AI185869.1 Clone IMAGE:1741904 lung 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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