> Tryptophanyl-tRNA synthetase (WARS)
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UGID:712758     UniGene Hs.497599     Homo sapiens (human)   WARS Order cDNA clone, Links
Tryptophanyl-tRNA synthetase (WARS)

Human protein-coding gene WARS. Represented by 2554 ESTs from 557 cDNA libraries. Corresponds to 4 reference sequences (different isoforms). [UniGene 712758 - Hs.497599]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_001158843.2 PREDICTED: tryptophanyl-tRNA synthetase, cytoplasmic isoform 6 P. troglodytes 100.0 470
NP_004175.2 WARS gene product H. sapiens 100.0 470
NP_001157960.1 tryptophan--tRNA ligase, cytoplasmic isoform 2 M. musculus 94.7 474
NP_001084545.1 tryptophanyl-tRNA synthetase X. laevis 88.0 474
NP_957066.1 wars gene product D. rerio 87.4 461
NP_524826.1 Tryptophanyl-tRNA synthetase, isoform B D. melanogaster 72.0 425
NP_507683.2 Protein WARS-1 C. elegans 69.7 398
NP_001078104.1 tryptophanyl-tRNA synthetase A. thaliana 68.8 390
XP_001697043.1 hypothetical protein CHLREDRAFT_192647 C. reinhardtii 68.2 402
XP_960902.1 tryptophanyl-tRNA synthetase N. crassa 65.4 416
NP_014544.1 tryptophan--tRNA ligase WRS1 S. cerevisiae 62.8 398
Other hits (2 of 60) [Show all]SpeciesId(%)Len(aa)
XP_001105725.1 PREDICTED: tryptophanyl-tRNA synthetase, cytoplasmic isoform 9 M. mulatta 99.0 474
XP_003902314.1 PREDICTED: tryptophan--tRNA ligase, cytoplasmic isoform 1 P. anubis 99.0 474

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; placenta; lung; uncharacterized tissue; testis; connective tissue; uterus; blood; skin; spleen; intestine; vascular; cervix; liver; mixed; kidney; stomach; lymph; embryonic tissue; mouth; pancreas; heart; prostate; eye; ascites; pharynx; trachea; thymus; mammary gland; lymph node; thyroid; bone marrow; muscle; bone; esophagus; bladder; salivary gland; adrenal gland; adipose tissue; ovary; parathyroid; larynx; amniotic fluid; umbilical cord; pineal gland; epididymis; nerve; pituitary gland; ganglia
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 14
Map position: 14q32.31
UniSTS entry: Chr 14 WI-12287 [Map Viewer]
UniSTS entry: Chr 14 RH70848 [Map Viewer]
UniSTS entry: Chr 14 WI-12109 [Map Viewer]
UniSTS entry: Chr 14 WARS_8724
UniSTS entry: Chr 14 RH44843 [Map Viewer]
UniSTS entry: Chr 14 RH103649
UniSTS entry: Chr 14 RH65341 [Map Viewer]
UniSTS entry: Chr 14 A007H17 [Map Viewer]
UniSTS entry: Chr 14 G35834
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (17)

BX248006.1 human full-length cDNA clone CS0DM004YH09 of Fetal liver of Homo sapiens (human) P
AK130698.1 Homo sapiens cDNA FLJ27188 fis, clone SYN02464, highly similar to Tryptophanyl-tRNA synthetase (EC 6.1.1.2) P
AK124668.1 Homo sapiens cDNA FLJ42677 fis, clone BRAMY2037971, weakly similar to Homo sapiens tryptophanyl-tRNA synthetase (WARS)
NM_004184.3 Homo sapiens tryptophanyl-tRNA synthetase (WARS), transcript variant 1, mRNA P
NM_213646.1 Homo sapiens tryptophanyl-tRNA synthetase (WARS), transcript variant 4, mRNA P
NM_213645.1 Homo sapiens tryptophanyl-tRNA synthetase (WARS), transcript variant 3, mRNA P
NM_173701.1 Homo sapiens tryptophanyl-tRNA synthetase (WARS), transcript variant 2, mRNA P
BC095453.1 Homo sapiens tryptophanyl-tRNA synthetase, mRNA (cDNA clone MGC:111225 IMAGE:30418785), complete cds PA
AK025487.1 Homo sapiens cDNA: FLJ21834 fis, clone HEP01596, highly similar to HSIFP53 Homo sapiens mRNA for IFP53 PA
M61715.1 Human tryptophanyl-tRNA synthetase (WRS) mRNA, complete cds P
AK056100.1 Homo sapiens cDNA FLJ31538 fis, clone NT2RI2000727, highly similar to TRYPTOPHANYL-TRNA SYNTHETASE (EC 6.1.1.2) P
BC017489.1 Homo sapiens tryptophanyl-tRNA synthetase, mRNA (cDNA clone MGC:15973 IMAGE:3542671), complete cds PA
AK291141.1 Homo sapiens cDNA FLJ75448 complete cds, highly similar to Homo sapiens tryptophanyl-tRNA synthetase (WARS), transcript variant 4, mRNA P
X59892.1 H.sapiens mRNA for IFN-inducible gamma2 protein P
AK300255.1 Homo sapiens cDNA FLJ58878 complete cds, highly similar to Tryptophanyl-tRNA synthetase (EC 6.1.1.2) P
X62570.1 H.sapiens mRNA for IFP53 P
M77804.1 Human tryptophanyl tRNA synthetase (IFNWRS) mRNA, complete cds P

EST sequences (10 of 2554) [Show all sequences]

AA863487.1 Clone IMAGE:1469422 uncharacterized tissue 3' read
AA961819.1 Clone IMAGE:1598437 uncharacterized tissue 3' read
AA971505.1 Clone IMAGE:1584369 lung 3' read
AA972230.1 Clone IMAGE:1584341 lung 3' read A
AA973089.1 Clone IMAGE:1579768 mixed 3' read P
AA974120.1 Clone IMAGE:1585592 lung 3' read
AA974263.1 Clone IMAGE:1586289 uncharacterized tissue 3' read A
AA975596.1 Clone IMAGE:1588911 kidney 3' read
AA975598.1 Clone IMAGE:1588919 kidney 3' read
AA988054.1 Clone IMAGE:1605188 lung 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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