> Dystrophin (DMD)
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UGID:711071     UniGene Hs.495912     Homo sapiens (human)   DMD Links
Dystrophin (DMD)

Human protein-coding gene DMD. Represented by 277 ESTs from 138 cDNA libraries. Corresponds to 18 reference sequences (different isoforms). [UniGene 711071 - Hs.495912]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_003997.1 DMD gene product H. sapiens 100.0 3684
NP_001005244.1 Dmd gene product R. norvegicus 100.0 621
NP_001084146.1 dystrophin, gene 1 X. laevis 97.6 633
NP_031894.1 Dmd gene product M. musculus 94.6 3677
NP_571860.1 dmd gene product D. rerio 91.3 588
NP_001036727.1 dystrophin, isoform E D. melanogaster 57.8 761
NP_492946.1 Protein DYS-1, isoform a C. elegans 53.2 357
Other hits (2 of 37) [Show all]SpeciesId(%)Len(aa)
XP_003917598.1 PREDICTED: dystrophin-like, partial P. anubis 98.8 1880
NP_001008055.1 dmd.1 gene product X. tropicalis 97.8 634

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; mixed; muscle; pancreas; liver; skin; ovary; prostate; ear; mouth; thyroid; uncharacterized tissue; cervix; heart; kidney; connective tissue; nerve; adrenal gland; trachea; testis; eye; embryonic tissue; intestine; pituitary gland; uterus; pharynx; placenta; vascular; lung; stomach; thymus; spinal cord; bone; spleen; lymph node; mammary gland
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: X
Map position: Xp21.2
UniSTS entry: Chr X A002S20
UniSTS entry: Chr X DXS6988E [Map Viewer]
UniSTS entry: Chr X PMC316713P2
UniSTS entry: Chr X G15848
UniSTS entry: Chr X DXS1234
UniSTS entry: Chr X DMD
UniSTS entry: Chr X DMD
UniSTS entry: Chr X DXS7499 [Map Viewer]
UniSTS entry: Chr X DMD
UniSTS entry: Chr X DMD
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (50)

AK129855.1 Homo sapiens cDNA FLJ26345 fis, clone HRT03668
NM_000109.3 Homo sapiens dystrophin (DMD), transcript variant Dp427c, mRNA PA
NM_004006.2 Homo sapiens dystrophin (DMD), transcript variant Dp427m, mRNA PA
NM_004007.2 Homo sapiens dystrophin (DMD), transcript variant Dp427l, mRNA PA
NM_004009.3 Homo sapiens dystrophin (DMD), transcript variant Dp427p1, mRNA PA
NM_004011.3 Homo sapiens dystrophin (DMD), transcript variant Dp260-1, mRNA PA
NM_004012.3 Homo sapiens dystrophin (DMD), transcript variant Dp260-2, mRNA PA
NM_004013.2 Homo sapiens dystrophin (DMD), transcript variant Dp140, mRNA PA
NM_004014.2 Homo sapiens dystrophin (DMD), transcript variant Dp116, mRNA PA
NM_004015.2 Homo sapiens dystrophin (DMD), transcript variant Dp71, mRNA PA
NM_004016.2 Homo sapiens dystrophin (DMD), transcript variant Dp71b, mRNA PA
NM_004017.2 Homo sapiens dystrophin (DMD), transcript variant Dp71a, mRNA PA
NM_004018.2 Homo sapiens dystrophin (DMD), transcript variant Dp71ab, mRNA PA
NM_004019.2 Homo sapiens dystrophin (DMD), transcript variant Dp40, mRNA P
NM_004020.3 Homo sapiens dystrophin (DMD), transcript variant Dp140c, mRNA PA
NM_004021.2 Homo sapiens dystrophin (DMD), transcript variant Dp140b, mRNA PA
NM_004022.2 Homo sapiens dystrophin (DMD), transcript variant D140ab, mRNA PA
NM_004023.2 Homo sapiens dystrophin (DMD), transcript variant Dp140bc, mRNA PA
NM_004010.3 Homo sapiens dystrophin (DMD), transcript variant Dp427p2, mRNA PA
BC070078.1 Homo sapiens dystrophin, mRNA (cDNA clone IMAGE:5262850), complete cds PA
M63072.1 Human Duchenne muscular dystrophy protein (DMD) mRNA, 3' end P
M92650.1 Human Duchenne muscular dystrophy (DMD) mRNA, complete cds P
M18533.1 Homo sapiens dystrophin (DMD) mRNA, complete cds P
AB208836.1 Homo sapiens mRNA for dystrophin Dp427c isoform variant protein P
BC094758.1 Homo sapiens dystrophin, mRNA (cDNA clone IMAGE:30336570), complete cds PA
BC127103.1 Homo sapiens dystrophin, mRNA (cDNA clone IMAGE:40124458), complete cds P
BC150141.1 Homo sapiens dystrophin, mRNA (cDNA clone IMAGE:40124455), complete cds P
AK309142.1 Homo sapiens cDNA, FLJ99183 P
BC028720.1 Homo sapiens dystrophin, mRNA (cDNA clone IMAGE:4822807), complete cds PA
X14298.1 Human mRNA for dystrophin P
AK299936.1 Homo sapiens cDNA FLJ60143 complete cds, highly similar to Homo sapiens dystrophin, transcript variant Dp140bc, mRNA P
BC010932.1 Homo sapiens dystrophin, mRNA (cDNA clone IMAGE:4273908), with apparent retained intron PA
BC009242.2 Homo sapiens dystrophin, mRNA (cDNA clone IMAGE:3029414), partial cds PA
S38776.1 Homo sapiens dystrophin (DMD) mRNA, partial cds, alternatively spliced
S42206.1 DMD=dystrophin {alternative first exon} [human, mRNA Partial, 120 nt]
S64152.1 dystrophin {5' region, alternatively spliced} [human, cerebellar Purkinje neurons, mRNA Partial, 320 nt]
S62617.1 dystrophin gene {alternatively spliced} [human, peripheral nerve, mRNA Partial, 106 nt]
S60973.1 dystrophin {out-of-frame deletion of exon 50} [human, fibroblasts, mRNA Mutant, 362 nt] P
S60972.1 dystrophin {out-of-frame deletion of exons 3-7} [human, lymphoblasts, mRNA Mutant, 144 nt]
S60971.1 dystrophin {out-of-frame deletion of exons 7-13} [human, lymphoblasts, muscle, mRNA Mutant, 234 nt]
X15148.1 Human mRNA for dystrophin isoform (partial)
X06179.1 Human fetal mRNA fragment of DMD gene (DMD= Duchenne muscular dystrophy) P
X06178.1 Human adult muscle mRNA fragment of DMD gene (DMD= Duchenne muscular dystrophy) P
M63075.1 Human Duchenne muscular dystrophy protein (DMD) mRNA, partial cds P
M63074.1 Human Duchenne muscular dystrophy protein (DMD) mRNA, 5' end
M63073.1 Human Duchenne muscular dystrophy protein (DMD) mRNA, 5' end
BC036103.1 Homo sapiens dystrophin, mRNA (cDNA clone IMAGE:5274415), complete cds PA
S71486.1 dystrophin [human, Duchenne muscular dystrophy patient, mRNA Partial Mutant, 162 nt]
S81419.1 dystrophin, dystrophin {Purkinje promoter, alternatively spliced} [human, cortical brain and adult heart, mRNA Partial, 377 nt]
X15149.1 Human mRNA for dystrophin isoform (partial)

EST sequences (10 of 277) [Show all sequences]

AA973017.1 Clone IMAGE:1577896 mixed 3' read A
AA906943.1 Clone IMAGE:1521685 lung 3' read
CB045405.1 Clone IMAGE:3218281 intestine 5' read
CB045404.1 Clone IMAGE:3218281 intestine 3' read A
CB177816.1 Clone IMAGE:6553129 pancreas 3' read P
AI307168.1 Clone IMAGE:1878544 mixed 3' read
AI307169.1 Clone IMAGE:1878546 mixed 3' read
AA770324.1 Clone 1322190 testis 3' read
AI342148.1 Clone IMAGE:1949692 uterus 3' read A
AI351524.1 Clone IMAGE:1940084 embryonic tissue 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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