> Transforming growth factor, beta receptor 1 (TGFBR1)
NCBI UniGene banner graphic
PubMed Nucleotide Protein Genome Structure Popset Taxonomy
 Search
NCBI

UniGene
Homepage
FAQs
Help
Query Tips
Build Info
Library Browser
DDD
Download UniGene

Related Databases
Gene
HomoloGene
EST
SRA

NIH cDNA Projects
MGC | ZGC | XGC
Finding cDNAs
UGID:709781     UniGene Hs.494622     Homo sapiens (human)   TGFBR1 Order cDNA clone, Links
Transforming growth factor, beta receptor 1 (TGFBR1)

Human protein-coding gene TGFBR1. Represented by 305 ESTs from 159 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 709781 - Hs.494622]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_001112621.1 PREDICTED: TGF-beta receptor type-1-like isoform 2 M. mulatta 100.0 502
XP_003911500.1 PREDICTED: TGF-beta receptor type-1 isoform 1 P. anubis 100.0 502
XP_001159299.1 PREDICTED: TGF-beta receptor type-1 isoform 3 P. troglodytes 100.0 502
NP_004603.1 TGFBR1 gene product H. sapiens 100.0 502
XP_538750.3 PREDICTED: TGF-beta receptor type-1 C. lupus familiaris 99.8 433
XP_001494957.2 PREDICTED: TGF-beta receptor type-1 E. caballus 99.5 433
NP_033396.1 Tgfbr1 gene product M. musculus 99.2 502
NP_001084084.1 transforming growth factor, beta receptor 1 precursor X. laevis 94.7 489
NP_001032772.2 tgfbr1a gene product D. rerio 90.9 494
NP_477000.1 baboon, isoform A D. melanogaster 69.8 480
NP_001023160.1 Protein DAF-1, isoform b C. elegans 50.9 161
Other hits (2 of 34) [Show all]SpeciesId(%)Len(aa)
NP_777046.1 TGFBR1 gene product B. taurus 99.4 498
NP_036907.2 Tgfbr1 gene product R. norvegicus 99.4 496

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; testis; uncharacterized tissue; uterus; mixed; prostate; embryonic tissue; ovary; placenta; intestine; stomach; pancreas; lung; kidney; bone; pituitary gland; vascular; mouth; eye; thyroid; connective tissue; liver; adrenal gland; skin; muscle; parathyroid; mammary gland; blood; lymph node; spleen; thymus; ear; heart; pharynx; lymph; ascites; bone marrow; nerve; cervix
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 9
Map position: 9q22
UniSTS entry: Chr 9 SHGC-34660 [Map Viewer]
UniSTS entry: Chr 9 RH45880 [Map Viewer]
UniSTS entry: Chr 9 RH35823 [Map Viewer]
UniSTS entry: Chr 9 RH69005
UniSTS entry: Chr 9 SHGC-12551 [Map Viewer]
UniSTS entry: Chr 9 RH121979
UniSTS entry: Chr 9 SHGC-12551 [Map Viewer]
UniSTS entry: Chr 9 Tgfbr1
UniSTS entry: GDB:437164
UniSTS entry: Chr 9 TGFBR1_1095
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (15)

AL117597.1 Homo sapiens mRNA; cDNA DKFZp564G2463 (from clone DKFZp564G2463) A
BC056247.1 Homo sapiens cDNA clone IMAGE:4073852, partial cds A
BX648917.1 Homo sapiens mRNA; cDNA DKFZp686E0660 (from clone DKFZp686E0660) A
AK129793.1 Homo sapiens cDNA FLJ26282 fis, clone DMC06777
NM_004612.2 Homo sapiens transforming growth factor, beta receptor 1 (TGFBR1), transcript variant 1, mRNA P
AJ619020.1 Homo sapiens partial mRNA for transforming growth factor beta receptor 1 (TBETAR 1 gene), short variant P
AJ619019.2 Homo sapiens mRNA for transforming growth factor receptor beta 1 (TBETAR1 gene), long variant P
AK002171.1 Homo sapiens cDNA FLJ11309 fis, clone PLACE1010076
BC071181.1 Homo sapiens transforming growth factor, beta receptor 1, mRNA (cDNA clone MGC:71700 IMAGE:30344890), complete cds PA
L11695.1 Human activin receptor-like kinase (ALK-5) mRNA, complete cds P
AJ420419.1 Homo sapiens mRNA full length insert cDNA clone EUROIMAGE 994846 A
AK302234.1 Homo sapiens cDNA FLJ58645 complete cds, highly similar to TGF-beta receptor type-1 precursor (EC 2.7.11.30) P
AK302059.1 Homo sapiens cDNA FLJ61454 complete cds, highly similar to TGF-beta receptor type-1 precursor (EC 2.7.11.30) PA
NM_001130916.1 Homo sapiens transforming growth factor, beta receptor 1 (TGFBR1), transcript variant 2, mRNA P
BC038347.1 Homo sapiens, clone IMAGE:4750477, mRNA A

EST sequences (10 of 305) [Show all sequences]

AA970535.1 Clone IMAGE:1573777 kidney 3' read A
AI017162.1 Clone IMAGE:1627574 mixed 3' read A
AI034411.1 Clone IMAGE:1647165 parathyroid 3' read A
AI080017.1 Clone IMAGE:1678798 skin 3' read A
AI096476.1 Clone IMAGE:1685670 brain 3' read A
CB054705.1 Clone IMAGE:3291826 brain 5' read
CB054704.1 Clone IMAGE:3291826 brain 3' read A
BX116411.1 Clone IMAGp998H206065_;_IMAGE:2439619 uterus A
CB143622.1 Clone L16HLK3-27-H02 liver 5' read
CB123053.1 Clone L10ChoCK0-17-B11 liver 5' read


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
NLM | NIH | UniGene | Privacy Statement | Disclaimer | NCBI Help