> COP9 signalosome subunit 5 (COPS5)
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UGID:707071     UniGene Hs.491912     Homo sapiens (human)   COPS5
COP9 signalosome subunit 5 (COPS5)

Human protein-coding gene COPS5. Represented by 703 ESTs from 263 cDNA libraries. Corresponds to reference sequence NM_006837.2. [UniGene 707071 - Hs.491912]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_038743.1 Cops5 gene product M. musculus 100.0 333
NP_001020866.1 Cops5 gene product R. norvegicus 100.0 333
XP_001368118.1 PREDICTED: COP9 signalosome complex subunit 5 M. domestica 100.0 333
XP_001097856.1 PREDICTED: COP9 signalosome complex subunit 5 isoform 5 M. mulatta 100.0 333
XP_003902883.1 PREDICTED: COP9 signalosome complex subunit 5 P. anubis 100.0 333
XP_001162723.1 PREDICTED: COP9 signalosome complex subunit 5 isoform 7 P. troglodytes 100.0 333
NP_006828.2 COPS5 gene product H. sapiens 100.0 333
XP_535093.1 PREDICTED: COP9 signalosome complex subunit 5 isoform 1 C. lupus familiaris 100.0 333
XP_001494265.1 PREDICTED: COP9 signalosome complex subunit 5 isoform 1 E. caballus 100.0 333
NP_001098770.1 COPS5 gene product S. scrofa 100.0 333
NP_001179068.1 COPS5 gene product B. taurus 100.0 333
XP_004011770.1 PREDICTED: COP9 signalosome complex subunit 5 O. aries 100.0 333
XP_002710500.1 PREDICTED: COP9 signalosome subunit 5 O. cuniculus 100.0 333
XP_003205144.1 PREDICTED: COP9 signalosome complex subunit 5-like, partial M. gallopavo 100.0 284
XP_003219681.1 PREDICTED: COP9 signalosome complex subunit 5-like A. carolinensis 100.0 269
NP_001232700.1 LOC100190188 gene product T. guttata 99.7 337
NP_001034400.1 COPS5 gene product G. gallus 99.7 337
NP_989109.1 cops5 gene product X. tropicalis 99.7 333
NP_957019.1 cops5 gene product D. rerio 99.4 331
NP_001086291.1 COP9 signalosome complex subunit 5 X. laevis 99.4 330
NP_477442.1 COP9 complex homolog subunit 5, isoform A D. melanogaster 83.3 323
NP_177279.1 COP9 signalosome complex subunit 5b A. thaliana 78.8 345
XP_001694818.1 COP signalosome subunit 5 C. reinhardtii 73.6 325
NP_500841.1 Protein CSN-5 C. elegans 72.4 319
XP_956786.1 COP9 signalosome complex subunit 5 N. crassa 66.7 306
Other hits (2 of 45) [Show all]SpeciesId(%)Len(aa)
XP_003967989.1 PREDICTED: COP9 signalosome complex subunit 5-like T. rubripes 99.4 332
XP_004081080.1 PREDICTED: COP9 signalosome complex subunit 5-like O. latipes 99.4 332

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; lung; testis; muscle; skin; pancreas; uterus; embryonic tissue; prostate; uncharacterized tissue; placenta; eye; pharynx; heart; mixed; intestine; kidney; lymph node; mouth; tonsil; bone marrow; ovary; liver; bone; mammary gland; thyroid; vascular; thymus; spleen; stomach; blood; connective tissue; ear; lymph; nerve; trachea; larynx; adrenal gland; ascites; umbilical cord; salivary gland; adipose tissue; parathyroid
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 8
Map position: 8q13.1
UniSTS entry: Chr 1 G35510
UniSTS entry: Chr 1 D1S1423
UniSTS entry: Chr 1 D1S1425
UniSTS entry: Chr 1 D11S3732
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (13)

BX648542.1 Homo sapiens mRNA; cDNA DKFZp779D1554 (from clone DKFZp779D1554) PA
AK128519.1 Homo sapiens cDNA FLJ46677 fis, clone TRACH3010079, highly similar to Homo sapiens COP9 constitutive photomorphogenic subunit 5(COPS5) P
NM_006837.2 Homo sapiens COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis) (COPS5), mRNA PA
CR541678.1 Homo sapiens full open reading frame cDNA clone RZPDo834D0428D for gene COPS5, COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis); complete cds, without stopcodon P
AB209134.1 Homo sapiens mRNA for COP9 signalosome subunit 5 variant protein P
BC001859.2 Homo sapiens COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis), mRNA (cDNA clone MGC:4661 IMAGE:3530890), complete cds PA
BC001187.1 Homo sapiens COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis), mRNA (cDNA clone MGC:3149 IMAGE:3354130), complete cds PA
BC007272.1 Homo sapiens COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis), mRNA (cDNA clone MGC:15591 IMAGE:3161025), complete cds PA
AK056967.1 Homo sapiens cDNA FLJ32405 fis, clone SKMUS2000390, highly similar to Homo sapiens 38 kDa Mov34 homolog mRNA P
AK311071.1 Homo sapiens cDNA, FLJ18113 P
AK310434.1 Homo sapiens cDNA, FLJ17476 P
U65928.1 Human Jun activation domain binding protein mRNA, complete cds PA
U70734.1 Homo sapiens 38 kDa Mov34 homolog mRNA, complete cds P

EST sequences (10 of 703) [Show all sequences]

AA903155.1 Clone IMAGE:1517674 uncharacterized tissue 3' read PA
AA973870.1 Clone IMAGE:1586534 uncharacterized tissue 3' read PA
AA988461.1 Clone IMAGE:1601917 lung 3' read P
AA995753.1 Clone IMAGE:1605217 lung 3' read A
R17665.1 Clone IMAGE:25386 brain 3' read A
AI004000.1 Clone IMAGE:1625206 embryonic tissue 3' read PA
AI024485.1 Clone IMAGE:1639587 testis 3' read PA
AI026741.1 Clone IMAGE:1644697 testis 3' read PA
AI033174.1 Clone IMAGE:1654471 mixed 3' read P
AI088509.1 Clone IMAGE:1696557 uterus 3' read PA


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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