> Natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A) (NPR1)
NCBI UniGene banner graphic
PubMed Nucleotide Protein Genome Structure Popset Taxonomy
 Search
NCBI

UniGene
Homepage
FAQs
Help
Query Tips
Build Info
Library Browser
DDD
Download UniGene

Related Databases
Gene
HomoloGene
EST
SRA

NIH cDNA Projects
MGC | ZGC | XGC
Finding cDNAs
UGID:705489     UniGene Hs.490330     Homo sapiens (human)   NPR1 Order cDNA clone, Links
Natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A) (NPR1)

Human protein-coding gene NPR1. Represented by 209 ESTs from 75 cDNA libraries. Corresponds to reference sequence NM_000906.3. [UniGene 705489 - Hs.490330]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_000897.3 NPR1 gene product H. sapiens 100.0 1060
XP_003308543.1 PREDICTED: LOW QUALITY PROTEIN: atrial natriuretic peptide receptor 1 P. troglodytes 99.8 1062
XP_002808282.1 PREDICTED: LOW QUALITY PROTEIN: atrial natriuretic peptide receptor 1-like M. mulatta 99.7 1060
XP_003892738.1 PREDICTED: atrial natriuretic peptide receptor 1 P. anubis 99.7 1057
NP_032753.5 Npr1 gene product M. musculus 95.1 1056
NP_001083703.1 natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A) precursor X. laevis 79.0 1053
NP_001038402.1 atrial natriuretic peptide receptor 1 precursor D. rerio 76.7 1021
NP_491380.1 Protein GCY-28, isoform b C. elegans 66.0 509
NP_726013.2 CG3216, isoform C D. melanogaster 55.6 833
XP_001697314.1 guanylate cyclase C. reinhardtii 51.9 188
Other hits (2 of 38) [Show all]SpeciesId(%)Len(aa)
XP_001915956.2 PREDICTED: atrial natriuretic peptide receptor 1 E. caballus 98.1 806
XP_002715543.1 PREDICTED: natriuretic peptide receptor 1 O. cuniculus 96.5 1055

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: mammary gland; placenta; uterus; ovary; intestine; lymph node; vascular; brain; mixed; kidney; uncharacterized tissue; embryonic tissue; connective tissue; trachea; testis; lung; muscle; adipose tissue; pancreas; thymus; heart; nerve; cervix; skin; ganglia
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 1
Map position: 1q21-q22
UniSTS entry: Chr 1 RH99065
UniSTS entry: Chr 1 RH68403 [Map Viewer]
UniSTS entry: Chr 1 G15870
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (7)

NM_000906.3 Homo sapiens natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A) (NPR1), mRNA PA
BC063304.1 Homo sapiens natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A), mRNA (cDNA clone MGC:71716 IMAGE:30331757), complete cds PA
AK025024.1 Homo sapiens cDNA: FLJ21371 fis, clone COL03174, highly similar to HSAANP Human mRNA for natriuretic peptide receptor (ANP-A receptor) PA
X15357.1 Human mRNA for natriuretic peptide receptor (ANP-A receptor) P
AK300446.1 Homo sapiens cDNA FLJ59428 complete cds, highly similar to Atrial natriuretic peptide receptor A precursor P
S72628.1 atrial natriuretic peptide receptor guanylate cyclase [human, retina, mRNA Partial, 1247 nt] P
AK298090.1 Homo sapiens cDNA FLJ51762 complete cds, highly similar to Atrial natriuretic peptide receptor A precursor P

EST sequences (10 of 209) [Show all sequences]

AA978089.1 Clone IMAGE:1590869 kidney 3' read A
AI003517.1 Clone IMAGE:1699119 kidney 3' read A
AI017916.1 Clone IMAGE:1629066 mixed 3' read
BX103209.1 Clone IMAGp998L132229_;_IMAGE:898332 kidney P
AI190837.1 Clone IMAGE:1732943 heart 3' read
R46850.1 Clone IMAGE:152523 mammary gland 5' read
AI367636.1 Clone IMAGE:1934533 embryonic tissue 3' read A
AI368110.1 Clone IMAGE:1934857 mixed 3' read A
AI379048.1 Clone IMAGE:2068390 mixed 3' read A
AI567201.1 Clone IMAGE:2191275 uterus 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
NLM | NIH | UniGene | Privacy Statement | Disclaimer | NCBI Help