Nicotinamide phosphoribosyltransferase (NAMPT)

NCBI

UniGene
Homepage
FAQs
Help
Query Tips
Build Info
Library Browser
DDD
Download UniGene

Related Databases
Gene
HomoloGene
EST
SRA

NIH cDNA Projects
MGC | ZGC | XGC
Finding cDNAs

UGID:704774 UniGene Hs.489615 Homo sapiens (human) NAMPT

Order cDNA clone, Links

Nicotinamide phosphoribosyltransferase (NAMPT)

Human protein-coding gene NAMPT. Represented by 1016 ESTs from 324 cDNA libraries. Corresponds to reference sequence NM_005746.2. [UniGene 704774 - Hs.489615]

SELECTED PROTEIN SIMILARITIES

Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.

Best Hits and Hits from model organisms		Species	Id(%)	Len(aa)
XP_519302.2 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: nicotinamide phosphoribosyltransferase isoform 3	P. troglodytes	100.0	490
NP_005737.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	NAMPT gene product	H. sapiens	100.0	490
NP_067499.2 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	Nampt gene product	M. musculus	97.8	490
NP_001089988.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	uncharacterized protein LOC735059	X. laevis	93.0	483
XP_002661386.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: nicotinamide phosphoribosyltransferase-like	D. rerio	90.4	480
Other hits (2 of 25) [Show all]		Species	Id(%)	Len(aa)
NP_001026963.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	NAMPT gene product	S. scrofa	98.4	490
XP_003896502.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: LOW QUALITY PROTEIN: nicotinamide phosphoribosyltransferase	P. anubis	98.3	524

GENE EXPRESSION

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.

	EST Profile:	Approximate expression patterns inferred from EST sources. [Show more entries with profiles like this]
	GEO Profiles:	Experimental gene expression data (Gene Expression Omnibus).
	cDNA Sources:	lung; blood; brain; liver; uncharacterized tissue; intestine; kidney; stomach; trachea; heart; mammary gland; spleen; uterus; placenta; thymus; connective tissue; pancreas; mixed; skin; prostate; vascular; amniotic fluid; thyroid; esophagus; testis; ascites; mouth; embryonic tissue; bladder; muscle; eye; lymph; ovary; parathyroid; nerve; ganglia; lymph node; adrenal gland; pharynx; larynx; cervix; bone marrow; bone; salivary gland; adipose tissue

MAPPING POSITION

Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.

Chromosome:	7
Map position:	7q22.3
UniSTS entry:	Chr 7	D7S2650
UniSTS entry:	Chr 7	A002U17
UniSTS entry:	Chr 7	SHGC-33423	[Map Viewer]

SEQUENCES

Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (7)

NM_005746.2	Homo sapiens nicotinamide phosphoribosyltransferase (NAMPT), mRNA	PA
BC072439.1	Homo sapiens nicotinamide phosphoribosyltransferase, mRNA (cDNA clone MGC:87988 IMAGE:6023159), complete cds	PA
BC106046.1	Homo sapiens nicotinamide phosphoribosyltransferase, mRNA (cDNA clone MGC:117256 IMAGE:6161081), complete cds	PA
AK292851.1	Homo sapiens cDNA FLJ76475 complete cds, highly similar to Homo sapiens pre-B-cell colony enhancing factor 1 (PBEF1), transcript variant 1, mRNA	P
U02020.1	Human pre-B cell enhancing factor (PBEF) mRNA, complete cds	P
L29050.1	Human G0S9 mRNA, instability elements
AK304085.1	Homo sapiens cDNA FLJ55038 complete cds, highly similar to Nicotinamide phosphoribosyltransferase (EC 2.4.2.12)	P

EST sequences (10 of 1016) [Show all sequences]

AA971751.1	Clone IMAGE:1583698	mixed	3' read	A
R17300.1	Clone IMAGE:31953	brain	5' read
AA946925.1	Clone IMAGE:1590154	kidney	3' read
AI093801.1	Clone IMAGE:1688451	mixed	3' read	A
AI129311.1	Clone IMAGE:1712818	uterus	3' read	A
CB052098.1	Clone IMAGE:3290334	uncharacterized tissue	3' read	A
CB052099.1	Clone IMAGE:3290334	uncharacterized tissue	5' read	A
CB052339.1	Clone IMAGE:3290166	uncharacterized tissue	5' read
CB052833.1	Clone IMAGE:3290537	uncharacterized tissue	5' read
AI220171.1	Clone IMAGE:1841393	mixed	3' read	A

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria