> Autophagy related 5 (ATG5)
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UGID:701222     UniGene Hs.486063     Homo sapiens (human)   ATG5
Autophagy related 5 (ATG5)

Human protein-coding gene ATG5. Represented by 305 ESTs from 182 cDNA libraries. Corresponds to reference sequence NM_004849.2. [UniGene 701222 - Hs.486063]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_001088076.1 PREDICTED: autophagy protein 5 isoform 2 M. mulatta 100.0 274
XP_003898015.1 PREDICTED: autophagy protein 5 isoform 1 P. anubis 100.0 274
XP_001144782.1 PREDICTED: autophagy protein 5 isoform 2 P. troglodytes 100.0 274
NP_004840.1 ATG5 gene product H. sapiens 100.0 274
XP_854294.1 PREDICTED: autophagy protein 5 isoform 1 C. lupus familiaris 99.6 274
NP_444299.1 Atg5 gene product M. musculus 98.9 274
NP_001009914.1 autophagy protein 5 isoform 1 D. rerio 83.9 272
NP_001085331.1 autophagy related 5 X. laevis 81.7 305
NP_572390.1 Autophagy-specific gene 5 D. melanogaster 52.3 264
Other hits (2 of 37) [Show all]SpeciesId(%)Len(aa)
XP_001503989.1 PREDICTED: autophagy protein 5-like isoform 2 E. caballus 99.3 274
NP_001029751.2 ATG5 gene product B. taurus 99.3 274

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; placenta; embryonic tissue; uncharacterized tissue; testis; spleen; uterus; eye; lung; mixed; mouth; esophagus; cervix; intestine; stomach; prostate; kidney; mammary gland; connective tissue; lymph node; heart; bone; pancreas; ovary; liver; trachea; thymus; bladder; skin; blood; lymph; ear; ascites; pharynx; muscle; bone marrow
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 6
Map position: 6q21
UniSTS entry: Chr 6 WI-20363 [Map Viewer]
UniSTS entry: Chr 6 EST6B12
UniSTS entry: Atg5
UniSTS entry: Chr 6 RH78069
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (15)

BX537904.1 Homo sapiens mRNA; cDNA DKFZp686F0183 (from clone DKFZp686F0183); complete cds PA
NM_004849.2 Homo sapiens autophagy related 5 (ATG5), mRNA P
AK001899.1 Homo sapiens cDNA FLJ11037 fis, clone PLACE1004316, highly similar to Autophagy protein 5 P
CR749386.1 Homo sapiens mRNA; cDNA DKFZp781D1825 (from clone DKFZp781D1825) PA
BC093011.1 Homo sapiens ATG5 autophagy related 5 homolog (S. cerevisiae), mRNA (cDNA clone MGC:110866 IMAGE:30345897), complete cds PA
BC002699.2 Homo sapiens ATG5 autophagy related 5 homolog (S. cerevisiae), mRNA (cDNA clone MGC:3622 IMAGE:3609927), complete cds PA
AF293841.1 Homo sapiens apoptosis-related protein (APG5L) mRNA, complete cds, alternatively spliced P
EU283339.1 Homo sapiens ATG5 autophagy related 5-like (ATG5) mRNA, complete cds, alternatively spliced P
EU283338.1 Homo sapiens mutant ATG5 autophagy-related 5-like (ATG5) mRNA, complete sequence P
AK315800.1 Homo sapiens cDNA, FLJ96922 P
AK299577.1 Homo sapiens cDNA FLJ50845 complete cds, highly similar to Autophagy protein 5 PA
JQ924061.1 Homo sapiens ATG5 (ATG5) mRNA, complete cds
JQ918353.1 Homo sapiens ATG5 variant 2 (ATG5) mRNA, complete cds
JQ918354.1 Homo sapiens ATG5 variant 3 (ATG5) mRNA, complete cds
Y11588.1 H.sapiens mRNA for apoptosis specific protein PA

EST sequences (10 of 305) [Show all sequences]

R14042.1 Clone IMAGE:26823 brain 5' read P
AI016984.1 Clone IMAGE:1624198 embryonic tissue 3' read A
AI017430.1 Clone IMAGE:1635689 kidney 3' read A
CB044559.1 Clone IMAGE:3217896 intestine 3' read A
CB044560.1 Clone IMAGE:3217896 intestine 5' read
CB050305.1 Clone IMAGE:3271731 prostate 3' read A
R24431.1 Clone IMAGE:131662 placenta 5' read
R24731.1 Clone IMAGE:35441 brain 5' read P
AI160403.1 Clone IMAGE:1721530 uterus 3' read A
BX099163.1 Clone IMAGp998J08160_;_IMAGE:35441 brain A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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